As a accutane user myself (its marketed as Roaccutane here in Australia) and with many friends who have also used the drug I'd say the most common long term side effect is dry lips, most of use always need to use lip barm. I havent used accutane in around 3 years but still have dry lips. Also dry eyes is quite common, I don't really have to use anything for this though moisturizing eye drops occasionally is a good idea if they are particularly dry. Beyond that I havent heard to many complaints, and it's done wonders for our skin
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