I've heard more than one poster comment that they didn't care for blends. I can't help but see how the positives outweigh any negatives, and I can't really see any negatives. Could someone enlighten me as to what would be the downside from taking a blend. The only one I can possibly see is that the dosage ratios are predetermined. You may want to do more of one and less of another and with a blend you can't change the dosage ratio.