"Kisspeptin Resets the Hypothalamic GnRH Clock in Men"
Results: Kisspeptin induced an immediate LH pulse, regardless of the timing of the previous endogenous
pulse. The kisspeptin-induced pulses were on average larger than endogenous pulses
(amplitude 5.0 1.0 vs. 2.1 0.3 mIU/ml, P 0.02). Comparison of the morphology of kisspeptininduced
LH pulses in healthy men with that of GnRH-induced LH pulses in men with isolated GnRH
deficiency suggests that a single iv bolus of kisspeptin triggered sustained GnRH release lasting
approximately 17 min. Furthermore, kisspeptin reset the GnRH pulse generator, as it not only
induced an immediate LH pulse but also delayed the next endogenous pulse by an interval approximating the normal interpulse interval.
http://jcem.endojournals.org/content/96/6/E908.short
Seems very promising in the sense of people who do several cycles seem to end up on TRT, Kisspeptin reset the 'clock' regulating the pulses of GnRH and the following pulses were also amped up, compared to the pulses before the addition of it. So in a sense it put the pit back in the puberty state with higher pulses which result in higher natural production of gonadotropins.
I dont know how well this would work in a PCT setting after a cycle, since it was only one administeration, and who knows after multiple suppressions then stimulations if it would work as well or what.
much more promising than the GnRHa (triptorelin) administeration IMO because to much of that can result in medical castration and kisspeptin seems to be the step before a GnRHa (since it releases the GnRH) instead of having a agonist of GnRH