bass: it's just so complicated...
That amazing organism within we live has so many feedback loops that once you try to affect one, the other ove-compensates.
Doesn't matter as long as everything is in an acceptable range.
For example, did you realize that SHBG very much likes to bind to E2? So high E2 levels are good because they reduce "free-SHBG" which then allows free-test to rise.
Not true, your using very vague terms, it may be that normal e2 levels reduce free SHBG and higher levels have no added positive effect, only negative
Or, maybe it's not good to have elevated E2 levels because they will inhibit the GnRH system to release less testosterone?
BTW, what is the NORMAL RANGE for E2 in individuals who regularly unbalance their HPTA by injecting test? For certain, it's not the one LabCorp or Quest uses based on "normal population studies," i.e. guys not using test. And its unlikely to be the one based on epidemiological studies.
Of course it would be the ones lab corp and others use, even if you found a happy medium between all the different suggested optimum levels. Just because the test is exogenous doesn't mean that we can no longer use levels associated with those who have good natural levels, who or what else would you want your levels to mimic? We base ALL our hormone levels on that scale, yes?
What is a good range for E2? Answer: one where you feel good and don't display any adverse symptoms. Might be 25...might be 45...might be 100.
Probably not 100, I think at this point you're flying in the face of experience and what the medical field has found to be normal.
Oh yeah, my last E2 was 27, but that was back when I used 150 mg test/week along with 750IU HCG and 1 mg adex. With my current protocol of 120 mg test, 0.5 mg Adex and 500 IU HCG per week, I'm going to do some BW next week, so TBA.
I've never had a hint of gyno, so I'm considering dropping the Adex and reducing the HCG to 350IU if things look good.
I'm all for NOT using an AI and I hope this works for you, my hope is that through being a guinea pig some of us will find a way to slow or even stop conversion with our dosing and schedules........on that point I think we agree 100% 