Why no drugs to boost shbg?

[Hydrolex]

Are there any drugs that boost shbg directly? Can't believe no pharma companies have come up with it... I heard about Capesaris but i think it failed

[kelkel]

None spring to mind. Simply getting older will do it though.

[The Deadlifting Dog]

thyroid meds raise SHBG

[1moreset024]

Why do you want to boost it? Doesn't high shbg tie up free test in blood?

[Youthful55guy]

thyroid meds raise SHBG

Agree, the data is pretty clear on this. The main limitation is the extent to which you can enhance thyroid hormones without unacceptable side-effects. My experience is each 30 mg of Armour Thyroid increased my SHBG by about 10 nmol/L, which was not good for me in that I had high SHBG to begin with. Long story covered in a different thread.

Be vary careful about introducing exogenous thyroid hormone. SLOW AN OVER TIME IS THE KEY TO SUCCESS. My only experience is with Armour Thyroid, and I would only recommend increasing doses of 15 mg at a time and no more sooner than 3 to 4 weeks apart.