Talk me out of MK 677

[yeahbuddy289]

Been doing a little bit of reading on this drug and a couple things concern me. First is not being able to recover natural levels if I discontinue use. Second is having a problem with insulin and becoming diabetic from using this.

I am not using aas for the time being... I’m sure this drug is much more effective when combined with aas but can I expect any sort of lean tissue gains while using this? The main draw for me is I have a ton of nagging joint injuries that just won’t heal. I’m hoping this drug would help significantly with that?

[GearHeaded]

I'm a huge fan of MK677 . have been using it for 5+ years. have lots of clients utilizing it as well. have plenty of guys on this forum I've turned on to it as well that love the stuff.

couple of notes
- its best utilized in a massing phase, or a muscle gain focused recomp. not suited for a cut (because it works via Ghrelin and will induce your appetite big time) . its the best appetite increaser that I know of (blows EQ away).. yes you will have much higher growth hormone and IGF levels, which have lipolytic benefits and can help with fat burning, the appetite stimulation for outweighs that and you'll eat a ton of food and blow your diet and not be able to cut.

- your going to gain weight . lot of guys put on an easy 10 pounds within a few weeks. you will hold water. this is a good thing if your massing and trying to put on size.

- your hands will start to go numb and you may have tingling sensations down your arms. this is from the inter cellular swelling around nerve canals.. yes 1" bigger biceps and bigger fuller traps is nice, but will cause nerve sensations.

- MK677 is not suppressive like test is suppressive to the HPTA . MK simply replicates GHRH (growth hormone releasing hormone thats secreted by the hypothalamus), and causes your Pituitary to pulse growth hormone. the minute you come off mk your hypothalamus will begin producing GHRH again.
now there is a negative feedback loop based on IGF levels . when your IGF levels get high, there is a signal that will tell your hypothalamus to not produce GHRH .. but MK is replacing GHRH anyhow and will keep your pituitary going even if IGF is high .

- MK does NOT induce diabetes. it doesn't even produce insulin resistance to any real degree (despite people saying it does) . now will your fasting blood sugars go up like 15+ points when on MK , even into what may be considered pre diabetic ranges , YES . but that does not mean your insulin resistant. your blood sugars are simply elevated because your natty HGH levels are elevated and HGH is an energy demanding/requiring hormone. HGH needs an energy source to work (building and repairing cells requires energy) . and whats the bodies most efficient energy source , glucose . so your blood sugars are elevated, not cause your diabetic, but because HGH is causing stored blood sugar to enter the blood stream so it can be used as energy . thats it . the minute you come off MK your blood sugars go back to normal.
note -- this is also how HGH is lipolytic . it releases fatty acids into the blood stream as an energy source. cause again HGH is an energy requiring hormone.


MK will help you put on muscle and size , I'd plan to run it for at least 4 months. yes it works better stacked with other drugs.

now being you can not run androgens right now . you could stack MK with Clen (not for fat loss), T4 (not for fat loss), and Insulin.. these 4 things all together are very synergistic and anabolic , yet will not suppress your hpta at all.
its basically a muscle building stack without actual steroids.


MK works best taken at night before bed. it also works best used with other nutrients .. a quality MK source will have things like Melatonin added in to their formula to help induce a greater pulse of GH . let me know if you need a quality source and discount code for MK (mike Arnold makes the best product out there right now imo)

[Windex]

My understanding is MK677 can be split into AM/PM doses. Mine is dosed at 15mg/tab so I do 1 tab with my morning meal to help kick start the appetite for the day and the other 15mg before bed. My concern with 30mg pre bed was the ghrellin spike in the middle of the night and waking up starving?

[GearHeaded]

My understanding is MK677 can be split into AM/PM doses. Mine is dosed at 15mg/tab so I do 1 tab with my morning meal to help kick start the appetite for the day and the other 15mg before bed. My concern with 30mg pre bed was the ghrellin spike in the middle of the night and waking up starving?

completely agree .. I have a few guys that are struggling to eat enough running 25mg pre bed , and 12.5 mg the next day.

the idea of waking up starving, when your trying to bulk and force feeding food anyhow, is a definite benefit . the feeling of being hungry when bulking is a big plus

[GearHeaded]

OP - I forgot to mention.. for the first few weeks of running MK , expect to be fairly lethargic and tired. all you want to do is eat and sleep . this goes away after about 3 weeks

[yeahbuddy289]

Damn gearheaded... on point as always. I totally trust your advice and I think I will give this a try. I know I won’t be putting on any crazy amount of size without aas... but I’m hoping it will help heal my joints and give me some relief?

Another question is should I wait to use this until I can cycle aas again? Like will I be wasting the potential “newb” gains by not running aas in conjunction with this?

As far as eating and sleeping.... that is basically all I want to do now anyways lol well not so much the eating lol

[GearHeaded]

if I was in your situation , I'd start MK677 tomorrow . it has a lot of upside for your current situation , theres no need to wait until you can run AAS again

[yeahbuddy289]

Will it still have the same effect if I run it again when I am able to cycle? I’d hate to miss out on the potential gains I could get with it while using aas.... kind of like someone who runs their first cycle of aas and doesn’t know how to train or diet... they miss out on the all potential gains you can make with a first cycle.

[Ashop]

My understanding is MK677 can be split into AM/PM doses. Mine is dosed at 15mg/tab so I do 1 tab with my morning meal to help kick start the appetite for the day and the other 15mg before bed. My concern with 30mg pre bed was the ghrellin spike in the middle of the night and waking up starving?

Personally speaking I could only tolerate 12.5 mg daily. It made me a little tired in the day if I took it AM and I cant afford being tired. The hunger is REAL!! The most intense hunger I have EVER experienced in all my days.

[Windex]

Personally speaking I could only tolerate 12.5 mg daily. It made me a little tired in the day if I took it AM and I cant afford being tired. The hunger is REAL!! The most intense hunger I have EVER experienced in all my days.

I can relate to the hunger. The nice part about being semi retired is not being chained to a work schedule so I can eat on my own terms.

[AR's King Silabolin]

Been doing a little bit of reading on this drug and a couple things concern me. First is not being able to recover natural levels if I discontinue use. Second is having a problem with insulin and becoming diabetic from using this.

I am not using aas for the time being... I’m sure this drug is much more effective when combined with aas but can I expect any sort of lean tissue gains while using this? The main draw for me is I have a ton of nagging joint injuries that just won’t heal. I’m hoping this drug would help significantly with that?

It will not fix injuries and even if ostarine is the weakest sarm, in short term it will give alot more size and strength than mk677.

Mk677 is best for long term use and run 9 months a year, it will boost your cycles.
It works pretty much the same as 2 IUs of HGH, i have red.

Im addicted to it and i love it.

Sent fra min BLA-L29 via Tapatalk

[yeahbuddy289]

Unfortunately I won’t be running gear again until after my girl gets pregnant... so I’m looking for something that will help me get some size and strength back. I thought it would help with my joints Sil, is that not the case??

[doping]

I would suggest MK-677 only to people over 40 yo.. or even older than that. For people who are starting to have problems with low bone mineral density etc.
If you are younger it can mess up your hormonal system (insulin and GHS receptors).
There is also a study which says that it does not promote growth in young mice due to somatostatin RNA overexpression: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/
Which basically means that your body is trying to fight and normalize the HGH level (with MK-677 your HGH stays high in blood for too long which is not normal).
So if you are young and use MK-677 it can even limit your growth velocity. HGH injections will have greater effects in younger people

[yeahbuddy289]

I am 30 years old. That is my main concern is messing up my natural hormones/insulin. Gear headed has a few studies showing it does not and I trust his information but just like aas, all that good comes at some price, some way.

[GearHeaded]

I would suggest MK-677 only to people over 40 yo.. or even older than that. For people who are starting to have problems with low bone mineral density etc.
If you are younger it can mess up your hormonal system (insulin and GHS receptors).
There is also a study which says that it does not promote growth in young mice due to somatostatin RNA overexpression: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/
Which basically means that your body is trying to fight and normalize the HGH level (with MK-677 your HGH stays high in blood for too long which is not normal).
So if you are young and use MK-677 it can even limit your growth velocity. HGH injections will have greater effects in younger people

the negative feed back loop that leads to Hypothalamus suppression of GHRH is the same wither your taking MK677 or exogenous HGH,, and thats primarily based on hepatic IGF output. if your liver is putting out lots of IGF the hypothalamus will shut down GHRH release. period (again no matter if your taking mk or exogenous HGH .. its the actual IGF output that causes the suppression).
the benefit of MK over HGH is that it will still at least stimulate the pituitary to produce natural HGH pulses. where as exogenous HGH will eventually shut down both the hypothalamus and the pituitary.

[GearHeaded]

I would suggest MK-677 only to people over 40 yo.. or even older than that. For people who are starting to have problems with low bone mineral density etc.
If you are younger it can mess up your hormonal system (insulin and GHS receptors).
There is also a study which says that it does not promote growth in young mice due to somatostatin RNA overexpression: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/
Which basically means that your body is trying to fight and normalize the HGH level (with MK-677 your HGH stays high in blood for too long which is not normal).
So if you are young and use MK-677 it can even limit your growth velocity. HGH injections will have greater effects in younger people

also to clarify, at least from my understanding.. MK is NOT shutting down insulin receptors at all. the whole idea that MK (or even HGH) makes a person insulin resistant is based on a total misunderstand of how natty HGH effects glucose metabolism (and lipolysis).
Yes your going to be running much higher blood sugar levels when using MK or HGH, but this is not because you suddenly became insulin resistant. its because HGH is an energy requiring hormone. it can't work without an energy source.. building and repairing cells and tissue does not happen out of thin air. it requires energy. and guess what the body is the most efficient at using for energy. glucose. so the raise in blood sugars is NOT because your insulin resistance all of the sudden, its because the elevated serum levels of HGH in your body requires energy and so glucose is released into the blood stream and elevated.
this is also how HGH is a "fat burner" (not technically true). again HGH is an energy requiring hormone, the secondary fuel source from glucose is 'fat' . so HGH is lipolytic. it releases fatty acids into the blood stream as a fuel source, just like it does glucose.


a simple test which I've done many a time .. if your running MK677 or exogenous HGH and your blood sugars are 20 points higher then normal (which would indicate insulin resistance), simply stop taking the MK for a few days and your blood sugar will drop to normal no problem. with real insulin resistance this does not happen. it takes months and diet changes etc. for real insulin resistance to be fixed.

[BG]

Don’t waste your money.

[GearHeaded]

Don’t waste your money.

why ?

if your MK is legit you can add about 8 pounds in a few weeks. now sure that may be a lot of water and glycogen retention and obviously not just muscle tissue, but when bulking those things help drive hypertrophy . plus the appetite stimulation from MK is stronger then anything else that I know of. super benefical for guys struggling to get all their meals in

plus the HGH release is 100% real. no chance of 'fake chinese' HGH because the HGH it produces is 100% natural and your own. heck even with pharm grade scripted HGH just because its from an exogenous source your body can build anti bodies to it and destroy it. with naturally released HGH its 100% bio available.

[99JT]

why ?

if your MK is legit you can add about 8 pounds in a few weeks. now sure that may be a lot of water and glycogen retention and obviously not just muscle tissue, but when bulking those things help drive hypertrophy . plus the appetite stimulation from MK is stronger then anything else that I know of. super benefical for guys struggling to get all their meals in

plus the HGH release is 100% real. no chance of 'fake chinese' HGH because the HGH it produces is 100% natural and your own. heck even with pharm grade scripted HGH just because its from an exogenous source your body can build anti bodies to it and destroy it. with naturally released HGH its 100% bio available.

I wanna say I jumped at least a good 5lbs running it for a couple weeks at the end of my last blast mostly water retention but strength did go up. Might have to give it another try myself.

[yeahbuddy289]

Gear headed I ordered from the site you recommended... they only sent me one bottle and said they would be filling back orders in a week. I have not taken it yet and was hoping you could advise me on the best way to take it? One pill in the morning and another one at night?

[GearHeaded]

2 pills (25mg) right before bed . thats it

[JuliusPleaser]

I love the stuff, been on for about 2 weeks, while doing carnivore (no carbs) and still getting insane pumps.