I have had red and dry eyes since the first time I used B5. I am not sure if it is from the B5 or not. My Doc claims I am not producing tears. He even put in tear duct plugs with no results. I just use b5 when I break out from a cycle. The dryness and stinging seems to get worse when I use it. I also seen where accutane side affects can be irreversible red eyes. This **** sucks. Some times my eyes look like I poured red paint in them. Any one else have this problem?