08-19-2005, 07:53 PM #1
what the hell happened to dutasteride??
hey i was just wondering what happened to dutasteride...a little while ago there was all this hype about it and now it seems like no one is talking about it...i am kinda curious becasue i take 1/4 of a proscar daily and it just doesnt seem to be working. i have been taking it for about a year and im not even sure ive noticed anything. so i am thinking about swiching to dutasteride, what do you guys think??
08-19-2005, 08:08 PM #2
Is that avodart? How do you know propecia isn't doing anything? Are you losing hair still? Propecia doesn't grow hair back....It's prevention.
08-19-2005, 08:55 PM #3
yes that is avodart...i think the proscar isnt working becasue i am still sheddding a decent amount...at least if it is i guess i would say i am not as happy with it as i thought i would be...i know it doesnt grow it back but to me it doesnt seem to be slowing it down so thats why i was thinking of avodart (dutasteride) let me know what you guys think....
08-20-2005, 12:42 AM #4
Arr will be releasing it soon.....I'm still working on the formula
08-20-2005, 01:37 AM #5
I found it online for $135/90 caps X .05mgs
08-20-2005, 01:39 AM #6
How does Dutasteride work?
Researchers have discovered that men who suffer from benign prostatic hyperplasia (BPH), or from male pattern hair loss, have increased levels of the hormone dihydrotestosterone (DHT).
DHT is produced from testosterone by an enzyme called 5-alpha-reductase. Biochemical analysis reveals higher levels of 5-alpha-reductase in the bloodstream of men with BPH, and in the scalps of men with hair loss; and less of this enzyme in men with no BPH or no hair loss.
Dutasteride inhibits 5-alpha-reductase, blocking the formation of DHT. This interrupts a key trigger element in both BPH and development of male pattern hair loss.
What is dihydrotesterone (DHT)?
DHT is one of several male hormones in the body. DHT is responsible for the development of the external genitals in the male foetus. However, in adult males DHT appears to cause:
male pattern hair loss
shortening of the growing phase of hair
progressive miniaturisation of hair follicles
decreasing number of visible hairs
How is Dutasteride different from Propecia?
Both medicines work in a similar way. However, Dutasteride inhibits the activities of two types of 5-alpha-reductase enzymes. In contrast, Propecia (Finasteride) only inhibits one type. Dutasteride has been shown to decreases levels of DHT by 90% after only two weeks, making it a more powerful and faster-acting weapon against BPH and hair loss than Finasteride.
What studies and trials have been done concerning Dutasteride?
A total of 2951 men with moderate to severe BPH were treated with 0.5 mg Dutasteride (dutasteride) daily. The study found that acute urinary retention was reduced by 57%, and the risk of benign prostatic hyperplasia-related surgical intervention was cut by 48% compared with placebo. The drug was shown to be well tolerated.
GlaxoSmithKline also completed Phase II trials for FDA approval of Dutasteride for treating hair loss. After six month of treatment, the hair counts measured in a 1 inch diameter circle increased by an average 96 hairs with 0.5mg Dutasteride daily, compared to an average 72 hairs with 5mg Propecia (Finasteride) daily.
So these initial trials show that Dutasteride is around 30% more effective than Propecia in promoting hair regrowth. Dutasteride is approved by the US FDA and by European bodies for the treatment of BPH, and so has passed all relevant safety standards. However, please note that Dutasteride has only been specifically approved for treating BPH. It has not yet been approved specifically for treating hair loss.
Will Dutasteride help hair re-growth for all men?
As with Propecia, Dutasteride increases the number of scalp hairs, helping to fill-in thin areas of the scalp. Although results will vary, generally men will not re-grow all of the hair they have lost. Male pattern hair loss occurs gradually over time, but Dutasteride can significantly reduce or delay hair loss. Note that Dutasteride is not yet approved for treating hair loss: its effects are a side-effect of its actions against BPH.
Is Dutasteride safe?
Clinical trials showed that it was generally well tolerated. Most side effects were mild or moderate and generally went away while on treatment in both the Dutasteride and placebo groups.
Dutasteride should not be used in women and children. Women who are pregnant or may become pregnant should not handle this medicine because of possibility of absorption and subsequent potential risk to a male foetus.
Men treated with Dutasteride should not donate blood until at least six months after their final dose to prevent the medicine going to a pregnant woman through a blood transfusion.
Men with liver disease should talk to their doctor before taking Dutasteride
08-20-2005, 04:19 AM #7Registered User
- Join Date
- Mar 2005
- west palm bch fla
Seattle Junk, where did you find dut for such a low price? Im planing on taking it during my next cycle. Also, have you found the generic versions of it to be effective and better than finas?
Lion, when do you think you will have it in stock? I definetly will order it asap.
08-20-2005, 10:56 AM #8Originally Posted by MrBigSh!T
Dutas [Generic Dutasteride]
Dr Reddy's Laboratories (India)
90 Caps x 0.5mg Total 45mg
Last edited by Seattle Junk; 08-20-2005 at 10:58 AM.
08-20-2005, 02:17 PM #9
i dont thing a generic for avodart is legal yet, becasue there patenet hasnt run out so i think i would be skeptical...let me know i might be wrong, and if i am i am defenitely interested in those dutas
08-20-2005, 05:38 PM #10Originally Posted by juict
08-21-2005, 10:05 AM #11
one of the main concerns with avodart was the sexual side effects. it really hurt libedo in a lot of men. some reports suggested this side effect may NOT go away with time. however, i did recently see it for sale on the website of a doc that does hair transplants.
08-21-2005, 11:03 AM #12
interesting that is one of my main conecerns though...i def. cant afford to be losing my sex drive
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