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  1. #1
    SexyKitty's Avatar
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    T3 - Split the dose or Not?

    What are everyone's thoughts on whether the daily dose of cytomel should be split or not?

    I've seen some people split it 1/2 am, 1/2 pm, and some take it all at once but there doesnt seem to be a consensus on what is preferable. Opinions on this?
    Last edited by SexyKitty; 09-22-2005 at 07:29 PM.

  2. #2
    Jerzey's Avatar
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    How much are you taking?


    I always spread it out....

  3. #3
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    i split mine up, once in the morn, once in the afternoon

  4. #4
    SexyKitty's Avatar
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    Quote Originally Posted by Jerzey
    How much are you taking?


    I always spread it out....

    50mcg right now but tapering up to 100mcg. Took it a year ago and had good results but my memory is sooooo bad, I cant remember if I split the dose or not

  5. #5
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    split it, especially when you go up. I've gone up to 125 and I always spread it out. At 50 I'd do one when I wake up and one early afternoon...(I get up early so it's half way through the day for me).

  6. #6
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    Quote Originally Posted by SexyKitty
    50mcg right now but tapering up to 100mcg. Took it a year ago and had good results but my memory is sooooo bad, I cant remember if I split the dose or not
    100mcg? wow...i sweat like mike tyson in a spelling bee on 50mcg/day

  7. #7
    spywizard's Avatar
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    all at once in the am.. otherwise i get too hot in the evening, and can't sleep..

    but that's me..

    Example 1
    An example for a 20-day cycle with a max of 100mcg ED using 25mcg pills. Calculate the number of days of each period first (Notice that where the up/down period is unable to be broken into 3 exactly equal parts, the extra is put on the dose level at the last part of the period. (.5) means 1/2 a pill or 12.5mcg

    UP CONST DOWN
    4 days 6days 10days
    5% 40% 55%
    2 44444444 33222111.5.5.5

    ______________________________
    Example 2
    An example for a 60-day cycle with a max of 125mcg ED using 25mcg pills. Notice that where the up/down period is unable to be broken into 3 exactly equal parts, the extra is put on the dose level at the last part of the period.
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  8. #8
    SexyKitty's Avatar
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    Quote Originally Posted by tonytone
    100mcg? wow...i sweat like mike tyson in a spelling bee on 50mcg/day
    I usually just get night sweats on 75 and up. I dont see results until I get to higher doses so I have to deal with it.

  9. #9
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    Quote Originally Posted by tonytone
    sweat like mike tyson in a spelling bee
    lmao

  10. #10
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    Quote Originally Posted by SexyKitty
    I dont see results until I get to higher doses so I have to deal with it.
    I'm at 100 now, I feel your pain.....

  11. #11
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    Quote Originally Posted by SexyKitty
    I usually just get night sweats on 75 and up. I dont see results until I get to higher doses so I have to deal with it.

    im seeing results at 50mcg/day, but i am dealing with terrible sweating...it's embarrasing, especially at school...dont even want to know what i would be like at 100mcg

  12. #12
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    are you guys running AAS with the T3?

  13. #13
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    Quote Originally Posted by mitch911
    are you guys running AAS with the T3?
    I am running GH and some AAS right now..

  14. #14
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    Quote Originally Posted by mitch911
    are you guys running AAS with the T3?
    yeah, i would not run t3 without any AAS

  15. #15
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    Liquid T3 has a half life of just around 2 hrs.So splitting the dose up as much as possible is a wise idea.When I'm at 100 mcgs,I'll split it in 4 doses.
    Obviously the pill form of Cytomel is better,since pharmacists add agents to slow the absorption rate down.

    ~Pinnacle~

  16. #16
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    Quote Originally Posted by Pinnacle
    Liquid T3 has a half life of just around 2 hrs.So splitting the dose up as much as possible is a wise idea.When I'm at 100 mcgs,I'll split it in 4 doses.
    Obviously the pill form of Cytomel is better,since pharmacists add agents to slow the absorption rate down.

    ~Pinnacle~
    really now??i did not know this...im going to try splitting it into more doses

  17. #17
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    T-3 has a half-life of about a day so all at once is fine. I have also read up to 2.5 days as well.
    Last edited by TheMudMan; 09-22-2005 at 09:11 PM.

  18. #18
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    Quote Originally Posted by TheMudMan
    T-3 has a half-life of about a day so all at once is fine. I have also read up to 2.5 days as well.
    Are you sure about the liquid version?I can't remember exactly where I saw a few posts showing the actual times....I know the pill forms half life is long like you stated.I was on a few medical sites that discussed cytomel and docs stated the reason pharmacists add slowing agents is for this reason of a short half life.So why then,would pharmacists slow down a drug that has a long half life as you say?

    ~Pinnacle~

  19. #19
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    Quote Originally Posted by Pinnacle
    Are you sure about the liquid version?I can't remember exactly where I saw a few posts showing the actual times....I know the pill forms half life is long like you stated.I was on a few medical sites that discussed cytomel and docs stated the reason pharmacists add slowing agents is for this reason of a short half life.So why then,would pharmacists slow down a drug that has a long half life as you say?

    ~Pinnacle~
    liothyronine sodium is the chemical used to make Cytomel I don't see why it being suspended in a liquid would have any difference in the way your body would metabolize it. I could be wrong but I just don't see it.

  20. #20
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    Quote Originally Posted by TheMudMan
    liothyronine sodium is the chemical used to make Cytomel I don't see why it being suspended in a liquid would have any difference in the way your body would metabolize it. I could be wrong but I just don't see it.
    I understand that MM.I've seen docs on med sites talking to ppl about T3(cytomel )and a few explained that cytomel is quick acting and in and out of your system quick.So pharmacists add slowing agents to this to keep it in thier system longer.So the average pill made,now stays in your system for around 24 hrs or even a little longer.
    My thinking says,well if it's put in solution,it must act quick and be out of your system rapidily.Since no slowing agent was used.Sort of see what I'm getting at?.......I'd like to know for certain myself.Maybe I'll ask on one of those Q & A doc sites.

    ~Pinnacle~

  21. #21
    TheMudMan's Avatar
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    Quote Originally Posted by Pinnacle
    I understand that MM.I've seen docs on med sites talking to ppl about T3(cytomel )and a few explained that cytomel is quick acting and in and out of your system quick.So pharmacists add slowing agents to this to keep it in thier system longer.So the average pill made,now stays in your system for around 24 hrs or even a little longer.
    My thinking says,well if it's put in solution,it must act quick and be out of your system rapidily.Since no slowing agent was used.Sort of see what I'm getting at?.......I'd like to know for certain myself.Maybe I'll ask on one of those Q & A doc sites.

    ~Pinnacle~
    That would be a good idea to ask because I have taken both and dosed them the same way and I would like to know for certain.

    T-3 is quicker acting then T-4. This is what I have read. I think t-4 has a half-life of close to a week. Maybe that's what you read?

    Either way let us know what you find out. Thanks!

  22. #22
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  23. #23
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    I take mine all at once in the AM before breakfast... Alot of people use to argue with me about that though...

  24. #24
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    Quote Originally Posted by roidattack
    Great link... Mallet threw his 2c.c.'s in as well.

  25. #25
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    Quote Originally Posted by Mesomorphyl
    I take mine all at once in the AM before breakfast... Alot of people use to argue with me about that though...
    Like who?

  26. #26
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    Quote Originally Posted by Pinnacle
    I understand that MM.I've seen docs on med sites talking to ppl about T3(cytomel )and a few explained that cytomel is quick acting and in and out of your system quick.So pharmacists add slowing agents to this to keep it in thier system longer.So the average pill made,now stays in your system for around 24 hrs or even a little longer.
    My thinking says,well if it's put in solution,it must act quick and be out of your system rapidily.Since no slowing agent was used.Sort of see what I'm getting at?.......I'd like to know for certain myself.Maybe I'll ask on one of those Q & A doc sites.

    ~Pinnacle~


    Kitty,

    Regardless of type (liquid/tablet) Mud is correct...
    Pharmacokinetics
    Since liothyronine sodium (T3) is not firmly bound to serum protein, it is readily available to body tissues. The onset of activity of liothyronine sodium is rapid, occurring within a few hours. Maximum pharmacologic response occurs within 2 or 3 days, providing early early response. The biological half-life is about 2.5 days.
    - King Pharmaceuticals, Inc

    http://www.kingpharm.com/uploads/pdf_inserts/Cytomel_PI.pdf#search='cytomel%20half%20life'

  27. #27
    Blown_SC is offline Retired Vet
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    I do it all in one dosage...

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