Thread: Liver protection by legumes
07-06-2005, 03:09 PM #1
Liver protection by legumes
Another reason to pic beans over rice and pasta as main carb source. Especialy when on orals.
Phytomedicine. 2001 May;8(3):213-9. Related Articles, Links
Evaluation of hepatoprotective activity of legumes.
Wu SJ, Wang JS, Lin CC, Chang CH.
Department of Health and Nutrition, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan, ROC.
Mung bean, adzuki bean, black bean and rice bean are foods and folk medicines of Taiwan. We evaluated the effects of various water extract concentrations (100, 500 and 1000 mg/kg body wt.) and silymarin (25 mg/kg body wt. on acetaminophen-induced liver injury by measuring serum glutamate-oxalate-transaminase (sGOT) and serum glutamate-pyruvate-transaminase (sGPT) activities in rats. The results showed that the sGOT and the sGPT activities, increased by APAP, were decreased significantly (P < 0.05) through treatment with inceasing amounts up to 1000 mg/kg body wt. of the exracts. In particular, the mung bean aqueous extract showed the best hepatoprotective effect on APAP-induced hepatotoxicity. The pathological changes of liver injury caused by APAP improved by the treatment with all of the legume extracts, which were compared to silymarin as a standardized drug. In addition to these results, the extract of mung bean acted as a potential hepatoprotective agent in dietary supply.
PMID: 11417915 [PubMed - indexed for MEDLINE]
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