Best steroids fo your joints?

[LAW]

Hooker your just awsome! You always write amazing interesting information. It is much appreciated.

[catlovesfood]

hooker, does LR3 IGF-1 heal joints, cartilage, ligaments, and tendons?

[IBdmfkr]

hooker, does LR3 IGF-1 heal joints, cartilage, ligaments, and tendons?

originaly posted by johnnyB in the IGF/GH forum... hope he doesnt mind me moving it to this particular post.


""""This was posted by soulsnatcher at Steroidology


IGF1 stands for insulin like growth factor. It mimics insulin in the human body and also at the same time makes the muscles more sensitive to insulin’s effects. It is a growth factor and is the most potent one in the human body at that. IGF causes muscle cell hyperplasia, which is an actual splitting and forming of new muscle cells. This was thought to only be possible during puberty. IGF is much more potent at this effect than growth hormone is, in fact almost all of the effects you see from growth hormone come from the increased amount of IGF that your liver produces when the GH is destroyed. So it would be very easy to say that IGF is a much more potent and cheaper alternative to GH use, although GH is more effective for fat loss than IGF due to some other effects that it causes such as metabolism increase and the ability to effectively use more insulin, T3, and anabolic steroids .

Another advantage that IGF has over GH is that it has much more of an affinity to attach to muscle cells instead of bone and organ cells. Growth hormone has been know to cause a lot of organ enlargement and bone elongation since it attaches to all types of receptor cells. IGF is much more likely to go where we want it, our muscle cells. IGF-1 attaches to myogenic stem cells which are only located in muscle and connective tissues. These myogenic stem cells are responsible for the production of myoblast cells which in turn are responsible for the buildup and repair of connective tissues (ligaments, tendons, cartilage, and joints to a certain extent).

So from this you can see that IGF-1 is great for increasing the strength of tendons and also for helping to heal existing injuries while at the same time helping to prevent them. IGF-1 is also responsible for increased protein synthesis and amino acid synthesis.

IGF does not have to be used along with anabolic steroids , GH, insulin, or thyroid hormones to be effective. It causes muscle growth on its own. In fact some people prefer to use it during their breaks from steroid cycles since IGF has no effect on natural test production. It could effectively be used along with HCG , clomid, and PGF2a for a hell of an off cycle stack which would allow your body to return to normal and still allow you to grow!! On its own IGF will give an increase of around 2 lbs. of new solid lean muscle tissue every two weeks, and is also is know for its ability to strip off body fat and GREATLY increase vascularity, body fat decreases of 5-8% over a 50 day cycle are not uncommon. But, of course you will be much happier with the results if you use the IGF along with anabolic steroids, testosterone , and insulin.

The use of steroids along with the IGF allow you to quickly mature and strengthen the new muscle tissue that the IGF has formed, and may also speed the process of hyperplasia. If you need any help setting up a great stack to
use along with the IGF just let me know and I can help you out. I speak with lots of top bodybuilders and guru’s so I am very knowledgeable.

The dosage issue for IGF is where the most controversy lies. Dosages used by competitive athletes most commonly range anywhere between 60mcg/day to 100+mcg/day. The trick is finding the dosage that works best for YOU. For most the best results appear when you reach a dosage of 80mcg/day, while some do
receive good results from only 40mcg/day. I personally feel the best results begin to be noticed at a dosage of 100mcg/day. I personally am using 150mcg/day during my current cycle.

Also I should let you know that the form of IGF is the Long R3 analog. It has been chemically altered and has a longer half-life than regular IGF, which only lasts about 10 minutes in the human body once injected. The Long R3 IGF-1 has a half-life of 6-10 hours, so you will only need to inject once or twice per day. The best time to inject is after lifting and in the morning, so it would be best to use half the dosage in the morning and the other half after lifting. This will take maximal advantage of IGF’s insulin
mimicking effects.

As posted by: WarLobo

JohnnyB""""

[catlovesfood]

thanks for that bro, one question - whats PGF2a?

[IBdmfkr]

honestly I'm not sure, but i dont think it was an important part of the direct point of that particular post. looks like something run Post Cycle.

[catlovesfood]

ok cool, thanks for helpin a brother out, cheers

[Property of Steroid.com]

hooker, does LR3 IGF-1 heal joints, cartilage, ligaments, and tendons?

Disturbingly, I read the last post trying to explain this, who was 1bdmfkr, reposting something JohnnyB posted, who was reposting something Soulsnatcher posted, who was reposting something WarLobo posted....there is a lot of misinformatin in it. At least, there is alot of information that I've been unable to confirm in any kind of reputable journals, or medical tests....

Now we at least know how misinformation gets proliferated on the boards. Nobody stopped to check if any of that is true before reposting it.

I think the lack of references and notation in that post speak volumes for it's credibility.

Hooker your just awsome! You always write amazing interesting information. It is much appreciated.

I'm really just looking for an invite with you and Jerzey when you guys go clubbing....I haven't seen her in ages....

[juicyr6]

Disturbingly, I read the last post trying to explain this, who was 1bdmfkr, reposting something JohnnyB posted, who was reposting something Soulsnatcher posted, who was reposting something WarLobo posted....there is a lot of misinformatin in it. At least, there is alot of information that I've been unable to confirm in any kind of reputable journals, or medical tests....

Now we at least know how misinformation gets proliferated on the boards. Nobody stopped to check if any of that is true before reposting it.

I think the lack of references and notation in that post speak volumes for it's credibility.



I'm really just looking for an invite with you and Jerzey when you guys go clubbing....I haven't seen her in ages....

wtf...dont be stingy...where is my invite

thanks again for the research...i was a state away and too busy to do the research...i was just throwing out a theory...

but hey what do i know...a year ago i was asking which needle to inject....

[IBdmfkr]

Incorrect information from a mod should probably be deleted then, wouldn't you say? If not then what posts are we supposed to confide in?

[Property of Steroid.com]

Incorrect information from a mod should probably be deleted then, wouldn't you say? If not then what posts are we supposed to confide in?

Perhaps a better question to ask would be "why is an Smod posting false information"? However, this leads to other questions also, doesn't it? If someone is spreading bad information, ought they be on staff?

I'll reserve comment on that issue.

However, you make a good point....I'd say, as I've always said, you never need to "trust me" or think I'm a "good bro" to trust in the information I post. I always include references and notation, not brotellegence*.

I don't really have time to dissect every incorrect point in that GH/IGF post, which isn't JB's fault for posting, but rather simply for not double checking the "facts" in it. I assume he trusted the dude who originally posted it, and that guy trusted the other guy, etc....all the way back down the line...

Anyway, here's one example of something I found in there that is reasonably easy to refute, off the top of my head:

So it would be very easy to say that IGF is a much more potent and cheaper alternative to GH use, although GH is more effective for fat loss than IGF due to some other effects that it causes such as metabolism increase and the ability to effectively use more insulin, T3, and anabolic steroids.

As a matter of fact, GH acts directly on the adipocyte (a cell that synthesizes and stores fat) to induce lipolysis (fat loss), which is pretty obvious because GH seems to decrease insulin sensitivity; while IGF-I on the other hand increases it, and more likely stimulates lipolysis via insulin-mediated pathways:


Growth Horm IGF Res. 2005 Feb;15(1):19-27.

Are the metabolic effects of GH and IGF-I separable?

Mauras N, Haymond MW.

Division of Endocrinology, The Department of Pediatrics at the Nemours Children's Clinic, 807 Children's Way, Jacksonville, FL 32207, USA. [email protected]

IGF-I mediates some, but not all of the metabolic actions of GH and it has both GH-like and insulin-like actions in vivo. GH and IGF-I both have a net anabolic effect in man enhancing whole body protein synthesis over a period of weeks and perhaps months. Both hormones favorably improve body composition in GH deficient subjects with an increase in lean body mass and decreased adiposity. This is also observed when IGF-I is given to patients with GH-receptor mutations. These compounds, however, have divergent effects on carbohydrate metabolism. A potent glucose lowering effect is typically observed after IGF-I administration, with improved insulin sensitivity with marked lowering of circulating insulin concentrations, whereas GH therapy is associated with mild compensatory hyperinsulinemia, a reflection of relative insulin resistance. The latter observation makes IGF-I a potentially more convenient anabolic agent to use in conditions where carbohydrate metabolism is more likely to be impaired. GH increases lipolysis as a direct effect of GH on the adipocyte, as well as lipid oxidation by increasing substrate availability. However IGF-I increases lipid oxidation only when given chronically, most likely as a result of chronic insulinopenia. These compounds have been tried in a variety of catabolic conditions in man and both hormones have been effective in reducing the protein wasting effects of glucocorticosteroids and mitigate some of the catabolic effects of severe hypogonadism in males. A comparison of these and other effects of these hormones is provided in this brief review. Subsequent studies are still needed to fully elucidate the safety and efficacy of IGF-I for use in humans.




Is that a huge mistake? Not really, but I think it's important, and I don't particularly need to go through the whole thing showing where else it has flaws to prove my point.


*Here's the best part of that erroneous IGF information thread, though...the one that should have everyone laughing their asses off, which is a prime example of brotellegence:

I speak with lots of top bodybuilders and guru’s so I am very knowledgeable.

I'm actually embarrassed that anyone would write something so stupid as that.

[IBdmfkr]

good points. I believe we all need to do our own research but a lot of us do not know where to look or what sites have reputable info. Where do you dig for information hooker?

[catlovesfood]

hooker, does LR3 IGF-1 heal joints, cartilage, ligaments, and tendons?

So....Does it?

[Property of Steroid.com]

good points. I believe we all need to do our own research but a lot of us do not know where to look or what sites have reputable info. Where do you dig for information hooker?

I don't go to the boards for information...I generally go to medical journals and medical textbooks. Sorry....

There's maybe 5 really great boards on the 'net. Alot of boards have decent information and/or are fun to hang out at, but they aren't great.

Brian (The owner) has spoken to me and he wants this board to be one of the top AAS-info boards on the net....so...to that end, he spent alot of money on the profiles forum, and after I take care of some other projects that I have to do (AAS-Writing related), I'm going to re-do the whole main page and do some other stuff. Remember, although I wrote the profiles in that forum, there's still misinformation to be removed from other areas. Maybe a whole new EDU forum also....

But misinformation and other things which only serve to take up space on this board will no longer have a home here.

There will also be some other major announcements, and changes to this board. I'll leave it at that, for people to take as they will. If this board is to be....tops on the 'net, alot of changes need to take place, and Brian recognizes that, but both he and I need to finish projects we have going on before he and I can devote the time (and make the changes) necessary to S.com.

[IBdmfkr]

sounds good, looks like you both have a lot of work to do..

[Property of Steroid.com]

sounds good, looks like you both have a lot of work to do..

The problem isn't a lack of knowledge or intellegence...it's getting together the personel who're needed in the right positions on this board (maybe this means making new user groups, or shuffling personel, and/or adding/subtracting same) to do the things Brian needs done. There are some really smart dudes on the 'net (way smarter than me)...but getting them to write something that doesn't take a PhD to understand, and is enjoyable to read...is, well...problematic, to date.

We have a starting point (here) and a goal...now we need to draw a map to get from A to B. Its not as easy as it sounds, believe me.


~anthony

[IBdmfkr]

Good luck, interested to see how it turns out.