asprin

**bulkyboy** · 03-31-2006, 04:31 AM

i heard that taking an asprin a day thins the blood,is this worth it while on gear?

**Testostack** · 03-31-2006, 05:07 AM

???...........i thought that aspirin was vaso and one of the main reason why stacked w/ ephedrine/caffein! so what that about?

***D7M*** · 03-31-2006, 06:34 AM

you're right, testo. imo, asprin is ok with gear, just not excessively.

**valcon** · 03-31-2006, 07:44 AM

doesnt some steroids thin the blood..........

**stupidhippo** · 03-31-2006, 11:53 AM

aspirin doesnt per se thin the blood but it inhibits coagulation which is one risk involved with viscous blood. Is it beneficial? in that sense it is but it also has potential side-efects in klong term use.. ulcers and such..

**taiotosh7** · 03-31-2006, 11:57 AM

Shoot....I was on sus and decca just a few months back while taking some pain meds for my back. I got the smallest cut above my eye and it would not stop bleeding for hours! It didn't coagulate at all, I had to super glue it man

**ascendant** · 03-31-2006, 12:07 PM

asprin is good when on drol cause of the extra blood volume increase you get on it. i don't know if it's necessary or even recommended on other gear. though doctors say an asprin a day is good for you, doctors also make their living off you being sick. in my opinion, take only what you need to counter the negative effects of gear and you'll be alright.

**Rookie1974** · 03-31-2006, 12:36 PM

Well as with all things its a bit complex, but I give it a shot.

1. First asprin taken in small daily doses (81mg) knocks out enzymes in the platelets (I think these are leukotrienes or Thromboxanes, would have to look it up). This inhibits the platelets ability to adhere to the walls of blood vessels. Platelets act kind of like corks...when you break a blood vessel, on a microscopic level, platelets plug it up.

2. Coagulation factors, made in the liver, crosslink the platelet "corks" thereby reinforcing the plug.

3. Testosterone inhibits coagulation factors.

So as you can see taking asprin while on Testosterone is adding fuel to the fire....No platelets and no coagulation factors. Your going to bleed like a stuck pig. Most people report being more prone to bleeding while on Test...

People take Asprin in small doses (81mg, not the 325 of normal asprin) to stop the vessels from plugging up.

Its not clear what would happens with long term test administration...Does it inhibit vessel plugging? Anybody want to volunteer for a study???? Id wouldnt mix the two just sounds bad and probably not going to prevent anything since it is the long term therapy that causes the benefits.

Asprin does not per say thin the blood...at least that I know of???

If you want more PM me

**Swifto** · 03-31-2006, 12:39 PM

My doctor told me injecting a synthetic testosterone will thicken the blood...

**stupidhippo** · 03-31-2006, 12:42 PM

leukotrienes and thromboxanes are not enzymes for one.. You are pretty much right in what you are trying to say but u got some details a bit off.
Secondly: I am not sure about your comment on aspirin adding to the fuel on test.. Things can be more complex..

**Rookie1974** · 03-31-2006, 12:42 PM

I think he is reffering to the increase in red blood cells, and yes it does that. Kind of two differnt topics that come together to form a bigger picture. This gets really complex....

**stupidhippo** · 03-31-2006, 12:45 PM

to swifto: It can do that cause it can raise the RBC count. That would make a possible blood clot more likely and aspirin on the other hand would make it less likely. To summarize it as is it useful or not... cant do.. If you would belong to a risk group of getting a cardaiic episode - then sure! (but in that case u shouldnt use AAS either way)

**Rookie1974** · 03-31-2006, 12:53 PM

Well it may not be an enzyme per say (it does not end in -ase) but it is a derivitive of Arachidonic Acid which is a fatty acid so I guess that would make leukotrienes and thromboxanes fatty acids...whats off??? Does the story change??

**stupidhippo** · 03-31-2006, 01:05 PM

first off aspirin inhibits the cyclooxygenase enzymes (cox-1 cox-2) and thus prevents the AA derivatives from being formed.. but it doenst affect the leukotrienes at all since they are at an upper part of the metabolic pathway.. so lets forget about them, they are controlld by the lipooxygenase enźyme(s). Prostaglandins (another AA derivatives) are involved in platelet aggreagtion (I think it was PGI2) and their production is inihibited by all NSAIDS. Aspirin then has another specific way to inhibit bloodclotting but I cant remember that (or is it even known). They also inhibit thromboxane formation but cant go into more detail in their function here in practivce.. Now this is how I remember it atleast...

**stupidhippo** · 03-31-2006, 01:08 PM

but yeah you were pretty much right (like I said). Im just dot fu...ng a bit. then I was a bit unsure of that reasoning behind that one statement.. Im not saying it insnt so but I am not sure it is either.. simply just stating that these things can sometimes be a bit complex and simple 1+1=2 logic doesnt always apply.

**Rookie1974** · 03-31-2006, 02:54 PM

COX-1 and COX-2 is inhibites thereby downregulating PGG2 and PGH2 which would normally make PGI2, TAX2, PGD2, PGE2, PGF2 are all inhibited. Yes, Lipoxygenase is a seperate AA pathway.

I guess we just Hijacked the *hit out of this man's thread....

So, its a matter of judgement call (unless you know of a study) do you take or not take low strgenth Asprin???

Good Luck with your studies!!!!

**Testostack** · 03-31-2006, 03:38 PM

Originally Posted by taiotosh7

Shoot....I was on sus and decca just a few months back while taking some pain meds for my back. I got the smallest cut above my eye and it would not stop bleeding for hours! It didn't coagulate at all, I had to super glue it man

The same on Tbol........just cut yourself by shaving and you'll be a fountain for next 2 hours

**8pak** · 03-31-2006, 04:20 PM

Originally Posted by Testostack

The same on Tbol........just cut yourself by shaving and you'll be a fountain for next 2 hours

Yeah, I'm on T-bol now and here's another down side: I pulled my left biceps badly last workout and I think actually bleed into the muscle--prob small tear, which would normally be no big deal. But add in some mild anti-coagulation (from gear, aspirin, etc) and you got a 1-2 wk setback! Now THAT'S a bummer! Oh well, you plays tha game, you takes ya chances. But I sure wouln't be going out and gobbling up a bunch of aspirin. Ya know?