d-bol under tounge?

[makembyte]

someone told me to desolve the dianabol under my tounge instead of just swallowing it does it even matter?

[redz]

I doubt that would be worthwhile.....

[makembyte]

diddnt think so. its all going to the same place anyway. just thought i'd ask thanks

[Big]

I've heard of people chewing the orals for better absorption, I've tried it and really didn't notice any difference as opposed to swallowing them other than the nasty taste some leave in your mouth.

[KeepingItBalanced]

The best part is when they get stuck in the grooves of your teeth and you can taste it for hours! hah. I take all pills with grapefruit juice... I think that can enhance absorbstion.

[kfrost06]

I take all pills with grapefruit juice... I think that can enhance absorbstion.

That is true, I remember reading a bit anthony roberts wrote about that and some medications actually warn you about drinking grapefruit with the pills because it increases the effective strength by absorbing more.

[jAcKeD!!!!]

best way is to break them in half take sallow them, .. it will disolve faster and hit you

[celticd]

i think a ug source sells sublingual tabs that have to be put in the mouth to dissolve rather than swollwing as they wont work if swallowed hole
never tried em so can say whats better,but id imagine its bs

[KeepingItBalanced]

That is true, I remember reading a bit anthony roberts wrote about that and some medications actually warn you about drinking grapefruit with the pills because it increases the effective strength by absorbing more.

That's where I got the idea from, a medication bottle of a strong prescription drug I had a while back when I was injured. It said not to take it with grapefruit juice, so I had to try it. Did some research and general concensus is it helps. Things like coffee can actually interfere

[makembyte]

thanx bros ill try the g-fruit and breaking them in half and see if i notice any difference.

[slayer1983]

on one websit e ive seen sublingual dbol but the pills you should swallow and read the insteuictions

[Jay-Ace]

There's a thread somewhere that goes into lengths about sub-lingual administration of 17-aa AAS's .... Don't do it, nothing to be gained unless it's been specifically designed to be taken in that way!!

I would suggest that the reason for not taking grapefruit juice with some meds could be that the increased acidity or even the presence of certain enzymes could alter the formulation, create nasty metabolites or possibly counteract the drug!! It could also be that that specific med is possibly time-release as with some thyroid meds.

[Ashop]

someone told me to desolve the dianabol under my tounge instead of just swallowing it does it even matter?

out of habit I chew mine then swallow.

[shifty_git]

That is true, I remember reading a bit anthony roberts wrote about that and some medications actually warn you about drinking grapefruit with the pills because it increases the effective strength by absorbing more.

Grapefruit slows down the action of the P450 pathways in the liver, so substances cleared from the body through those pathways slowed and held in the body longer... so good for certain orals..

but..

P450 pathwyas are also used by estrogen and progesterone.. so grapefruit juice can also make them be held in the body longer...

[Jay-Ace]

Grapefruit slows down the action of the P450 pathways in the liver, so substances cleared from the body through those pathways slowed and held in the body longer... so good for certain orals..

but..

P450 pathwyas are also used by estrogen and progesterone.. so grapefruit juice can also make them be held in the body longer...

Not in the liver dude, in the intestines!!

Grapefruit contains Bergamottin, the culprit in your example, which inactivates the P450 3A4 enzyme... Meaning the drug gets a free ride past the "first pass" oxidative breakdown in the GI tract. Grapefruit doesn't noticeably affect liver enzyme levels.

[DavidYork2]

Is your tounge in the lounge?

[Jay-Ace]

Is your tounge in the lounge?

[shifty_git]

Not in the liver dude, in the intestines!!

Grapefruit contains Bergamottin, the culprit in your example, which inactivates the P450 3A4 enzyme... Meaning the drug gets a free ride past the "first pass" oxidative breakdown in the GI tract. Grapefruit doesn't noticeably affect liver enzyme levels.

Good point jay, was going from memory from a while ago and remembered 3a4 is present in both liver and colon.. rememberd the wrong one which was effected! lol

[makembyte]

out of habit I chew mine then swallow.

thats what my wife does but first she nibbles

[kfrost06]

Not in the liver dude, in the intestines!!

Grapefruit contains Bergamottin, the culprit in your example, which inactivates the P450 3A4 enzyme... Meaning the drug gets a free ride past the "first pass" oxidative breakdown in the GI tract. Grapefruit doesn't noticeably affect liver enzyme levels.

awesome post jay! thanks for the info

[Ashop]

someone told me to desolve the dianabol under my tounge instead of just swallowing it does it even matter?

some just swallow them,,,others chew them first,,,some do sublingual

[crazyivan]

done it both way, it didnt make a difference and i wont bother with that again

[CheddaNips]

best way is to break them in half take sallow them, .. it will disolve faster and hit you

Thats what i did and it worked.

My buddy told me bout this article how a Rec drug addict (pills) used to "parachute" his pain killers. He then became clean and did this with his first cycle of d-bol. "parachuting" is when you crush up your d-bol (or whatever) and twist it up in a piece of toilet pper and swallow it.

I found it weird. I will have to post up the article and run it past Merc or someone to see what they think. Proably no different effects.