Atenolol to Lower Side Effects of Clenbuterol?

[Dann]

Would taking a β1 receptor specific antagonist like Atenolol help reduce (or eliminate) the adverse effect of a rise in blood pressure while using Clenbuterol ?

In theory I think it would work. My thinking is that given Clen is selective by stimulating almost exclusively β2 receptors and hypertension (or BP in general) can usually be reduced by blocking the β1 receptors that there should be no reduction in effectiveness of either drug.

Am I correct in this assumption or not? If not can you please give me your reason why?



Also, I am aware that with both drugs there are peripheral effects on other beta receptors (β1 & β3 with Clen and β3 with Atenolol), but to a substantially low degree. I am assuming however, these minor overlaps will relatively cancel each other out.



edit: I already did a search on Google and this forum, but came up with nothing to answer this question.

[Dann]

Ok I just found this:
http://www.patentstorm.us/patents/55...scription.html

"The Effect of Beta-agonists and Beta-antagonists on Muscle Growth and Body Composition of Young Rats (RATTUS SP.)


...2. Neither propranolol nor atenolol blocked the effect of clenbuterol on muscle mass but both reduced its effect on cardiac and fat mass and energy expenditure."

But this is one study, and was performed on rats, not humans. We all know that Clen produces different overall effects on humans vs animals due to differences in beta receptors.


Can anyone provide more evidence either for or against my hypothesis?

[almostgone]

From what I understand and from what I remember reading, the use of any beta-blocker greatly reduces the effects of clenbuterol /albuterol.

AG