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  1. #1
    DieselLeo's Avatar
    DieselLeo is offline Junior Member
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    FINA and ANTi E's

    I am about to start my cycle which includes Test Enanthate , D-bol, EQ, Winnie and Fina. As of now I am planning on using Arimidex as my anti estrogen. Will Arimidex work well against Fina gyno ? Or should I try to get my hands on Bromine or Teslac or Novladex ? Thanks for the help

  2. #2
    McBain is offline Member
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    No you should get some bromo to have on hand. I'd have nolv on hand too.

  3. #3
    nj_'s Avatar
    nj_
    nj_ is offline Senior Member
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    If you can get dostinex over bromo I'd take it, less side effects, less dosages. Arimidex will do nothing for prolactin induced gyno so better have the bromo (or dostinex) on hand.

  4. #4
    dizzle's Avatar
    dizzle is offline Respected Member
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    I did a search on dostinex, looks like a viagra alternative.

  5. #5
    nj_'s Avatar
    nj_
    nj_ is offline Senior Member
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    Here's a study on the advantages of Dostinex over Bromocriptine, Where did you see this data of it being a viagra alternative, dizzle?

    Until Dostinex became available in the U.S., the only other dopamine agonist approved for the treatment of prolactinomas and/or hyperprolactinemia was bromocriptine. However, Dostinex has proved to have a number of advantages over bromocriptine:

    Lower incidence of side effects
    Twice weekly dosing versus 2-3 times daily for bromocriptine
    Generally more effective, especially in those in which bromocriptine was ineffective

    Disadvantages of Dostinex over Bromocriptine

    Dostinex is twice as expensive as bromocriptine
    Dostinex is not available in all countries
    Dostinex is not approved for use during pregnancy, and its effects on pregnancy are unknown at this time

    Side Effects

    The side effects associated with Dostinex usually disappear or are reduced after a few doses. However, if you miss a dose, you may experience some of the original side effects for a short time. The most common side effects of Dostinex are:

    Nausea
    Dizziness
    Sleepiness
    Headache
    Stuffy nose
    Clinical Trial Results

    Webster et al., 1994. Comparison of cabergoline and bromocriptine in the treatment of hyperprolactinemic amenorrhea. N Engl J Med 31: 904-909.

    459 women with either microprolactinoma or idiopathic hyperprolactinemia were treated with Dostinex or bromocriptine in a double blind study for eight weeks.

    Results:

    Attainment of normal prolactin levels: 83% on Dostinex 59% on Bromocriptine

    Attainment of ovulatory cycles or pregnancy: 72% on Dostinex 52% on Bromocriptine

    Return of monthly periods: 93% on Dostinex 84% on Bromocriptine

    Dostinex had significantly less side effects with shorter duration and less severity that bromocriptine. Only 3% of women on Dostinex quit treatment because of side effects versus 12% that stopped treatment due to intolerance on bromocriptine.
    Biller BMK, et al. 1996. Treatment of prolactin secreting macroadenomas with once weekly agonist cabergoline. J Clin Endocrinol Metab 81: 2338-2343.

    15 patients (8 women, 7 men) were treated with Dostinex, once weekly, for 48 weeks.

    Results:

    A 93.6% reduction in prolactin levels, with normal levels obtained in 73% of patients
    5 patients who had previously been unable to achieve normal prolactin levels on other dopamine agonists, achieved normal prolactin levels on Dostinex
    gonadal function was restored in all hypogonadal men
    75% of premenopausal women with amenorrhea experienced return of gonadal function
    11 of 15 patients experienced tumor shrinkage
    minimal side effects – no patients discontinued Dostinex because of intolerance
    Colao, A. et al. 1997. Long-term and low-dose treatment with cabergoline induces macroprolactinoma shrinkage. J Clin Endocrinol Metab 82(11): 3574-3579.

    23 patients with macroprolactinomas Results:

    normalization of prolactin levels in 18 patients within 3-6 months at 0.5 mg/week
    tumor volume reduction greater than 80% occurred in 61% of patients at the 12-24 month follow-up
    the complete disappearance of the tumor occurred after 6 months in one patient and after 1 year of treatment in 5 patients
    visual field defects were improved in 90% of patients who experienced them
    Conclusions

    In general, the data suggests that Dostinex is a better tolerated and a more effective dopamine agonist that bromocriptine in the treatment of prolactinomas. Dostinex effectively lowers prolactin levels and shrinks tumor size in a high percentage of cases, making it a good first option in the treatment of both micro- and macroprolactinomas.

  6. #6
    Vaj10's Avatar
    Vaj10 is offline Associate Member
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    hey dumbass...how many times do i have to tell you i have our bromo on hand! lol see you tomorrow... miami was cool

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