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08-17-2009, 03:22 AM #1
steroids effect on melanoma or any other cancer?
hey everyone.
i have posted this along time ago since seeing a lot more members there is more knowledgeable people here now.
question
after having melanoma and getting it removed got all clear.(8 months ago) i get regular check ups scans on the lymph nodes.
can steroids (e.g. test C) NOT GROWTH HORMONES effect this
new growth of cancer?
lower immune system?
will they know if taking steroids for example inflamed lymph nodes ?
any other issues?
this is important
thanks
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08-17-2009, 03:50 PM #2
bump
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08-17-2009, 03:59 PM #3
Its a risk for sure.
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08-17-2009, 06:20 PM #4Member
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i read a study stating that trenbolone and winstrol are toxic to lymphocytes, which may compromise your immune system. A lot of steroids increase the production of IGF, and HGH too perhaps, not sure on that one.
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08-17-2009, 06:28 PM #5
Sorry man - don't have an answer for yah but i would definately like to know. I'll be following this thread.
~Haz~
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08-17-2009, 06:30 PM #6Member
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i do worry about this myself, ive had things removed, not yet cancerous, but dysplastic (pre cancerous, abnormal cell aggregation )
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08-18-2009, 12:28 AM #7
yeah it's a tricky one.
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08-18-2009, 11:21 AM #8New Member
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Test will speed up the growth of cancer. My dad has prostate cancer(already spread) the first thing they did was cut off his balls to eliminate his own test production.
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08-18-2009, 11:23 AM #9
^ Any information to back that up
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08-18-2009, 11:42 AM #10test will speed up the growth of cancer. My dad has prostate cancer(already spread) the first thing they did was cut off his balls to eliminate his own test production.
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08-18-2009, 01:26 PM #11Banned
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08-18-2009, 02:10 PM #12
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08-18-2009, 02:21 PM #13
Testosterone DOES NOT speed up CANCER in any way shape or form.
My Father, who has been on TRT for something like 15 years or whatever, was diagnosed WITH prostate cancer... the first thing they did after the admission of the Chemotherapy was INCREASE his Testosterone dosage from 200mgs EW to a staggering 400mgs EW... NOW I have never ever ever heard of this ever happening to anyone ever before. NEVER thought that was a NORMAL Testosterone procedure.. but I guess.. I dunno they figured he needed it.. They also prescribed him DECA to prevent wasting... BUT.. They were not allowing him to self administer.. he had to go into the hospital to receive his injection treatments.
This was all new to me, I never KNEW they did this sort of thing.. but I guess the CHEMO does something in regards to cause WASTING to happen and with the administration of this compounds stops the process... My Father never lost a POUND during his whole treatment of Chemo.. NOT 1lb. !!
He has been in remission now for 6 years.. he has these Quarterly Checkups and stuff.. once they found him to be in full remission they dropped the DECA and returned him to his normal Dose of TRT.
SO... If AAS played any role in speeding up or causing cancer they DEFINITELY would not have been treating my father with them.
So that's all I pretty much know on this issue...
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08-18-2009, 02:26 PM #14
Testosterone (and estrogen) both can increase the risk of deveoping cancer.
FACT.
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08-18-2009, 02:29 PM #15
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08-18-2009, 02:42 PM #16
That may be true.. then why did the MEDICAL PROFESSIONALS... INCREASE his Testosterone dosage... AND... add Nandrolone Decanoate??
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08-18-2009, 02:43 PM #17
And isn't NOLVADEX an ANTI BREAST CANCER Drug???
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08-18-2009, 03:00 PM #18
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08-18-2009, 03:03 PM #19
Oestrogenic steroids and melanoma cell interaction with adjacent skin cells influence invasion of melanoma cells in vitro.
Neil SM, Eves P, Richardson B, Molife R, Lorigan P, Wagner M, Layton C, Morandini R, Ghanem G.
University Section of Medicine, Division of Clinical Sciences, Northern General Hospital, Sheffield, UK. [email protected]
The invasion of melanoma is complex and multi-staged and involves changes in both cell/extracellular matrix (ECM) and cell/cell interactions. Female steroids and alpha-MSH have also been reported to influence metastatic melanoma progression, but their mechanisms of action are unknown. Accordingly, our aim was to establish in vitro models to examine (a) the influence of sex steroids and alpha-melanocyte-stimulating hormone (alpha-MSH) on tumour invasion and the influence of (b) ECM proteins and (c) adjacent cells on melanoma invasion. In the first model, melanoma cell invasion through fibronectin over 20 hr under serum-free conditions was used to investigate the effects of 17beta-oestradiol and oestrone on the invasion of human melanoma cell lines, A375-SM and HBL. A375-SM, but not HBL cells, proved very susceptible to inhibition by female steroids. However, invasion of the HBL line was inhibited by alpha-MSH. Using the second model of reconstructed human skin based on de-epidermised acellular dermis, we found that the HBL cells on their own failed to invade into the dermis (irrespective of the presence or absence of the basement membrane). However, there was a significant synergistic interaction between keratinocytes, fibroblasts and HBL cells, such that a modest invasion of HBLs into the dermis was seen within 2 weeks when other skin cells were present. In contrast, A375-SM cells showed a significant ability to invade the dermis in the absence of other cells, with less invasion when other skin cells were present. In summary, these models have provided new information on the extent to which melanoma cell invasion is sensitive to oestrogenic steroids and to alpha-MSH and to interaction, not only with adjacent skin cells but also to the presence of basement membrane antigens.
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08-18-2009, 03:23 PM #20
Last time my grandma checked with the pharmacist when she saw my nolvadex pills he said it was........ LMAO
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08-18-2009, 03:29 PM #21
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08-18-2009, 03:29 PM #22
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08-18-2009, 03:31 PM #23Member
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cancer is not as simple as everyone would make it sound. Theres so many different types. Some are responsive to hormones, other aren't.
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08-18-2009, 03:35 PM #24
True^
I just think if someone has had issues with any type of cancer in the past i would think long and hard before self administering any type of hormone which may or may not have an effect
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08-18-2009, 08:14 PM #25
thanks for the info guys much appreciated. all those things mentioned articles and post was what was running through my head.
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08-18-2009, 08:32 PM #26Junior Member
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Why don't you ask your doc?
There is a Medical centre on Harris st CBD sydney which specializes in Athletes in particular body builders etc.. I'm sure with his experience in this area he would be a good person to talk to about risks..
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08-18-2009, 10:04 PM #27
yeah not a bad idea mate. i will make a booking for my local doctor too.
thanks
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08-19-2009, 01:44 AM #28
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08-19-2009, 03:27 AM #29
yeah that would be the smartest idea
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08-19-2009, 10:02 AM #30New Member
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it is not bs. they also have pellets they can implant in the prostate to kill the test . believe what you want.
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