Many of you have asked me about injection pain!

[Expert]

This is advice I find myself giving repeatedly on how to prevent injection pain.

First, there are five primary causes of injection pain.

1) High Benzyl Alcohol content.

Benzyl Alcohol (BA) is used to increase the lipid solubility of esterfied compounds and to prevent bacteria growth in the oil. Most UGL's use excess BA or only BA as the co-solvent, due to it's modest price. Unfortunately, it can cause the destruction of cells and significant localised pain and inflammation. The discomfort is characterised by fairly rapid onset of a painful, red, swollen area. This can be ameliorated by diluting the compound with sterile cutting oil (grapeseed, cottonseed, sesameseed). A 1:1 ratio often works well.

2) Precipitation of short estered compounds

The shorter an ester, the less solubility is has in oil. This necessitates higher concentrations of BA to prevent the compound from 'crashing' out of solution. When the oil is injected, the BA is absorbed from the location of the oil depot. This caused the active compound to precipitate fine crystals within the muscle. The onset of this pain is often 4-12 hours after injection and is characterised by a hard, red, swelling at the injection site. To prevent this an additional co-solvent is needed, Benzyl Benzoate. BB maintains solubility of the esterfied compound past the point at which BA has been removed, preventing crystaline precipitation. Most UGL's don't add this to their compounded oils due to the higher cost. If added at approximately 20% by volume you can prevent most associated short ester pain.

3) High concentration (mg/ml)

Per above, Long ester = high solubility, short ester = less solubility. Human grade pharmaceutical hormones are almost never dosed higher then 200mg/ml for long esters (cypionate ). To increase the concentration, a larger amount of BA is necessary as a co-solvent. This can result in a similar reaction to that caused by short esters with pain and swelling as the BA is absorbed and solubility decreases and precipitation occurs. In this instance you don't 'need' the additional co-solvent (BB, but it still helps!). Instead, you can simply dilute the compounding oil with sterile cutting oil to lower the concentration to within the solubility for that ester.

4) Fascia displacement

This occurs when a large volumetric quantity is injected into a single site. The oil pushes the muscle fascia apart and results in stretching and eventually scarring with the muscle. This can be avoided by reducing single site injection volume and spreading the injections between multiple sites. This is also a good idea as more smaller, more frequent dosing significantly reduces many of the side effects of AAS. These become exacerbated by peak and troughs in hormone levels. The reduction in side effects is particularly dramatic with trenbolone acetate when an ED injection schedule is maintained.

5) Histamine reaction

This doesn't occur as often, but is still a potential possibility. For a compound to become biologically active the ester must be cleaved from the parent molecule. This results in the formation of a carboxylic acid. Some people find that they are sensitive to one of these. This results in swelling, warmth, redness and possibly a rash at the injection site. In the worst instance the individual may have an existing allergy to the carrier oil (sessame, etc...) that can result in anaphylaxis (swelling and occlusion of the airway) in addition to localised inflammation. If any histamine reaction results, immediately discontinue use and switch to an alternate carrier oil and/or alternate ester. If anaphylaxis results, immediately seek medical attention.


Ultimately I break these down into the following set of rules.

1) Dilute compound with sterile cutting oil to get mg/ml at <=200 for long esters and <=100 for short esters.
2) Add 20% Benzyl Benzoate by volume to propionate and phenylpropionate esters.
3) Use a 23g needle to prevent high output pressure from smaller needles
4) Inject very slowly to reduce muscle fascia displacement
5) Inject frequently w/ less volume, <3ml for large muscles and <2ml for smaller muscles
6) Rotate sites every time (I use six sites)
7) Gently warm the oil to improve viscosity
8) Ensure that the injection is deep intra-muscular and fully through any sub cutaneous fat

You can also add:
100mg benadryl one hour prior to injection
800mg ibuprofen one hour prior to injection

However, the ibuprofen will reduce the activity of autocrine based transcription and activity of PGE and PGF so continued use can result in less muscle hypertrophy.

[Big]

many of us have asked you about injection pain? you give this advice repeatedly? you joined about an hour ago and can't even receive pm's yet.

[Kibble]

many of us have asked you about injection pain? you give this advice repeatedly? you joined about an hour ago and can't even receive pm's yet.

LOL. That is what I was thinking. Because it is hard to find injection advice on this board.......

[ArmedHammerd]

many of us have asked you about injection pain? you give this advice repeatedly? you joined about an hour ago and can't even receive pm's yet.

lol looks like we got an expert here lmfao if you need to know about squats his thread about squats will help you also lmfao

[Big]

yeah because it's obvious in the hour he's been here that we don't know how to squat

[ArmedHammerd]

yeah because it's obvious in the hour he's been here that we don't know how to squat

yup i guess not what a joke wouldnt b surprised if he is just a kid trying to make a name for himself omfg http://forums.steroid.com/showthread...ghlight=squats

[Expert]

dont hate....and yes i have been asked by several of the guys from this site about injections...is this the only site in the world???????? NO ITS NOT.....OPEN YOUR MIND AND THINK BEFORE YOU SPEAK

[Kibble]

Who here has asked you for injection advice? You should remember since you have been here for less than a day. So tell me- who has asked you. Just tell me 5 people out of the abundance who have

[Kibble]

Looks like you are a "Copy and Paste" guru anyway

[Expert]

Who here has asked you for injection advice? You should remember since you have been here for less than a day. So tell me- who has asked you. Just tell me 5 people out of the abundance who have

LMAO!!!!!!!! POOR STUPID GUY!...As I have just stated...think before you speak! I have never been contacted on " THIS " site..I want to see if you are smart enough to figure this out? LMAO!!!!!!!!!!!!!!

[Expert]

Looks like you are a "Copy and Paste" guru anyway

Edited

[Big]

I forgot more than you will ever know fat azz!

making friends right off the bat, huh? I take it you don't plan on sticking around here...

[ArmedHammerd]

making friends right off the bat, huh? I take it you don't plan on sticking around here...

lmfao looks like its time to put the hammer down this guy is a troll people like this give us a bad name

[Big]

just another banned member back to cause problems, he's on his way out