Liver Protector

[migs03]

Whats the absolute best product to use for the 4 week dbol kicker at 30mg ed for liver protection?

[Big]

I like Liv52

[Bonaparte]

NAC. Take 2-3g a day.

[gym_junki]

I like Liv52

x2..

[HawaiianPride.]

Synthergine, Liver Longer, Liver Juice, Liv52, ALA, SAMe, Sesamin, Essential Forte ect ect..

Liv52 is all I stick with.

[tballz]

I take ursodeoxycholic acid (UDCA). It's the best thing out there for liver protection and it lowers cholesterol.

[Bonaparte]

I take ursodeoxycholic acid (UDCA). It's the best thing out there for liver protection and it lowers cholesterol.

I was about to buy some last time I was loading up on ancillaries, but ended up cheaping out. Do you have any studies on it?

[HawaiianPride.]

I was about to buy some last time I was loading up on ancillaries, but ended up cheaping out. Do you have any studies on it?

TUDCA:

5) Tauroursodeoxycholic acid (TUDCA) - this is a relatively recent new liver aid , introduced in the market as a supplement by thermolife(LIVER LONGER) it looks like a very good help in preventing cholestasis, one of the major risk with 17 alkylated steroids :

TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCα?ezrin pathway

Cholestasis, induced by liver ischemia-reperfusion injury (IRI), is characterized by dilatation of bile canaliculi and loss of microvilli. Tauroursodeoxycholic acid (TUDCA) is an anti-cholestatic agent, modulating protein kinase C (PKC) α pathway. PKC reduces ischemic damage in several organs, its isoform α modulates ezrin, a key protein in the maintenance of cell lamellipoidal extensions. We evaluated the effects of TUDCA on cholestasis, canalicular changes and PKCα?ezrin expression in a rat model of liver IRI. Livers flushed and stored with Belzer solution or Belzer + 10 mm TUDCA (4 ?C for 6 h) were reperfused (37 ?C with O2) with Krebs?Ringer bicarbonate + 2.5 μmol/min of Taurocholate or TUDCA. Bile was harvested for bile flow assessment. Liver tissue was employed for Electron Microscopy (EM) and for PKCα and ezrin immunoblot and immunofluorescence. The same experiments were conducted with the PKCα inhibitor Go-6976. TUDCA-treated livers showed increased bile flow (0.25 ? 0.17 vs. 0.042 ? 0.02 μl/min/g liver, P < 0.05) and better preservation of microvilli and bile canalicular area at EM. These effects were associated with increased PKCα and ezrin expression (P = 0.03 and P = 0.04 vs. control respectively), as also confirmed by immunofluorescence data. PKCα inhibition abolished these TUDCA effects. TUDCA administration during IRI reduces cholestasis and canalicular damage in the liver modulating PKCα?ezrin pathway.


http://www.blackwell-synergy.com/doi...ournalCode=tri

dosage required: 2 X 250 mg ed with meals

[Bonaparte]

Bile flow harvesting??? Those poor rats...
Thanks HP.