can AIs damage your HPTA?

[sikkestkuntouthere]

im 21. ran letro before. can AIs actually damage your HPTA?

or are AIs g2g

[doc w]

Great question, from personal experience I ran some letrizole for six months to try to get rid of some gyno. My test was on the lower side to begin with, but three years after letrizole it was around 50 percent of my original value. There is going to be some rebound estrogen after stopping AI which in theory may suppress HPTA. All I am giving u is anectodal evidence

[gixxerboy1]

i dont see how it would be. Bonapart or swifto could probably give a more detailed explanation. But from everything i kknow i dont see how it could be.
Why were you using letro?
What do you mean gtg? Are you using them alone?

[sikkestkuntouthere]

i dont see how it would be. Bonapart or swifto could probably give a more detailed explanation. But from everything i kknow i dont see how it could be.
Why were you using letro?
What do you mean gtg? Are you using them alone?

no i used letro for gyno. but i got tested again and my T levels were in the 400s, before they were in the 700s. granted i didnt get enough sleep this time but still.

i got my estro checked however and it was perfect at 25. but i didnt get it checked before, so it could've been higher.

[sikkestkuntouthere]

Great question, from personal experience I ran some letrizole for six months to try to get rid of some gyno. My test was on the lower side to begin with, but three years after letrizole it was around 50 percent of my original value. There is going to be some rebound estrogen after stopping AI which in theory may suppress HPTA. All I am giving u is anectodal evidence

the rebound sucked. im thinking about doing another letro run. its really stupid to recommend nolva. i should have went with aromasin from the start. nolva didnt do jack shit for me.

the reason im asking is because i want to run the letro again but this time much milder dosages (maybe 0.5mg twice a week) and do this for 3-4 weeks and then finish it off with aromasin. i still have a tiny lump in my left nipple (happened because of the estro rebound).

[Bonaparte]

Depends on how you do it and what AI you used.
I can only imagine a few hypothetical ways in which an AI could harm the HPTA, mainly involving extended periods of time and coming off abruptly. But if done right, AIs can boost test a lot (temporarily).

[sikkestkuntouthere]

just got my blood work back from last week. T is back in the high 500s and i assume its slowly heading to where it was (700-800).

BUT my estradiol is high. range was <130pmol/l. my levels are 140.. i can only imagine what it will be once my T levels are back at normal values.

my estradiol when i had T in the low 400s was 95 btw. currently on a cut. going to try get real lean, usually i stay around 10-11% but maybe getting down to 7% will help with the estradiol. if not i will go back to my endo again. maybe he will prescribe me adex/aromasin . if he does so ill use it as an opportunity to run the letro with it.