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Thread: Edema in my legs while on winnie
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05-10-2014, 03:50 PM #1
Running prop 300 ew Winnie 50 ed been on 3 weeks now and all of a sudden I've got this swelling in my legs mostly my calves. I took a oxycodon 40mg yesterday (the kind with no acetaminophen) I've never experienced this b4...
Is this a liver issue?!?!Last edited by 1wheelr1; 05-10-2014 at 03:54 PM.
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05-10-2014, 04:03 PM #2
Also I just cut my water back to 1.5 gallon from 2 a day. Should I stay at 2 or more?
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05-10-2014, 05:15 PM #3
Did you notice the swelling after you took the oxy? Opiates make you retain serious water
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05-10-2014, 05:18 PM #4
Pshhh, I wish I'd get water retention only in my calves. Sure beats a billion calf raises only to never be satisfied with them
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05-10-2014, 06:32 PM #5Originally Posted by madmuscler
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05-10-2014, 06:33 PM #6Originally Posted by RangerDanger830
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05-10-2014, 06:37 PM #7
I know what you mean, I was just messing around in a poor attempt at keeping these forums somewhat entertaining while still educational. Liver problems do cause water retention but usually only when your liver is pretty bad off. There are a few possible culprits, your diet being another one. The only way to rule out your liver unfortunately is bloodwork.
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05-10-2014, 06:42 PM #8
At this point I believe it was the oxy. My diet is on point I have a show in 2 weeks.
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05-10-2014, 07:31 PM #9
Why did you take that?
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05-10-2014, 07:33 PM #10Senior Member
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Is it painful?
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05-11-2014, 01:44 AM #11Originally Posted by AshopRep
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05-11-2014, 06:30 AM #12
Why do opiates cause water retention??
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05-11-2014, 07:57 AM #13
Copy and pasted
Opiates can cause peripheral edema and the effect is dose-related. The exact mechanism of opiate-induced edema is unclear but the following plausible mechanisms may be involved: a) by causing histamine release, morphine results in venodilation and this effect is dose-related (Grossman, 1996, Gardener-Nix 2002); b) opioids cause vasopressin release from posterior pituitary and this results in antidiuresis and retention of fluids leading to edema; and c) it's been shown in animals that by activating central opioid receptors, opioids enhance renal tubular sodium reabsorption -- this can cause edema and may block the aquaporins leading to retention of water (Huidoboro, 1981).
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05-11-2014, 11:00 AM #14Originally Posted by madmuscler
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05-11-2014, 01:43 PM #15
No problem
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05-11-2014, 01:58 PM #16
Wish all my threads were answered so precisely!
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