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  1. #1
    mesophyte is offline Junior Member
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    AI Dose Change (with blood work)

    I'm on 500mg of test e per week. I've been taking 1mg of anastrozole per week (I open 1 capsule and dilute in 7cc water and take 1 cc per day). It works out to roughly 0.142mg per day.

    My blood work came in and my E2 is at 127 pg/mL (range: up to 43 pg/mL) Is it enough to increase my dose of Anastrozole to 0.5mg per day or should I maybe take a full 1mg capsule to try and get this down asap?

    EDIT AUGUST 22: Just got my new results in. After doubling my dose to 0.25mg per day, my E2 actually doubled and is at 256pg/mL
    Last edited by mesophyte; 08-22-2014 at 08:10 AM.

  2. #2
    RangerDanger830's Avatar
    RangerDanger830 is offline Knowledgeable Member
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    Well the best thing to do is to try a higher dose of the Adex, then get more bloodwork to confirm whether that is working or not. That would give you enough information to have an accurate dose of AI.

    If you do not plan on getting bloodwork again during the cycle I would just suggest bumping it up to .25mg ED. I have done .5mg daily with powerful cycles but with just a few hundred mg of Test E you shouldn't need too much more.

  3. #3
    numbere is offline RETIRED- Knowledgeable member
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    You should follow RD's advise. Try 0.25mg ED for 7-10 days then have labs again.
    Last edited by numbere; 08-09-2014 at 12:44 PM.

  4. #4
    mesophyte is offline Junior Member
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    I was worried so yesterday I took 0.5mg and today I took 1mg. I'll go down to 0.25mg tomorrow and test my E2 again at the end of the week.

    My anastrozole is from Growth Company / GC (Mexican lab). They don't include any dessicant packs in the bottles and one of the pills I opened was completely empty. This combined with my blood work results has me a bit concerned about the quality of the product and wonder if it is possible underdosed or completely bunk. This is a worrying thought because my PCT drugs are GC as well. On the other hand, they are very well known and popular in my country.

  5. #5
    m314 is offline Junior Member
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    I've gotten bad liquidex before. I kept upping and upping the dose while E2 levels got higher and higher. You'll know one way or the other if you raise your dose and get bloodwork done again in a couple weeks.

  6. #6
    RangerDanger830's Avatar
    RangerDanger830 is offline Knowledgeable Member
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    You could always go with ARR at the top of the page, tried and tested and great.

  7. #7
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    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by rangerdanger830 View Post
    you could always go with arr at the top of the page, tried and tested and great.
    x2...
    -*- NO SOURCE CHECKS -*-

  8. #8
    Bio-Active's Avatar
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    Adex at .25 mg eod would be better. Getting your estrogen level to 40 pg/ml may not be the best idea because that is the reference range for a male with normal testosterone levels . Your testosterone levels are much higher closer to probably 3,000 ng/dl.
    Last edited by Bio-Active; 08-09-2014 at 03:05 PM.

  9. #9
    Cuz's Avatar
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    I agree with Jim

  10. #10
    xzed is offline Junior Member
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    Hey.i have same shit. I use 500 mg testo+400 deca . My blood level was 75. I used 1mg ed arimidex +20 mg nolva ed for a week. Than left nolva continue with arimidex 0.5 mg eod. After 2 week my eustro level decrease to 57. Its crazy. I think I have high aromatase activity. It could be same for you. I don agree with other comments. Your high testo level doesnt mean high ostro wont do anything. High ostro is high ostro. We have to decrease to normal range. My basal level is 9. So I am trying 1mg ari ed+20 nolva ed for a week again than continue with 0.75mg eod. I already got some gyno symptoms. Maybe you are not prone to gyno but still examine your self and be carefull about gyno.

  11. #11
    mesophyte is offline Junior Member
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    Quote Originally Posted by RangerDanger830 View Post
    You could always go with ARR at the top of the page, tried and tested and great.
    Unfortunately I can't import that kind of thing into my country, it is illegal and if it gets stopped by customs it would not be a good thing for me.

    Quote Originally Posted by jim230027 View Post
    Adex at .25 mg eod would be better. Getting your estrogen level to 40 pg/ml may not be the best idea because that is the reference range for a male with normal testosterone levels. Your testosterone levels are much higher closer to probably 3,000 ng/dl.
    I was taking slightly more than 0.25 EOD by taking 0.142mg ED. That's the dose I was on when I got the 127 pg/mL E2 result.

    Quote Originally Posted by xzed View Post
    Hey.i have same shit. I use 500 mg testo+400 deca. My blood level was 75. I used 1mg ed arimidex+20 mg nolva ed for a week. Than left nolva continue with arimidex 0.5 mg eod. After 2 week my eustro level decrease to 57. Its crazy. I think I have high aromatase activity. It could be same for you. I don agree with other comments. Your high testo level doesnt mean high ostro wont do anything. High ostro is high ostro. We have to decrease to normal range. My basal level is 9. So I am trying 1mg ari ed+20 nolva ed for a week again than continue with 0.75mg eod. I already got some gyno symptoms. Maybe you are not prone to gyno but still examine your self and be carefull about gyno.
    I don't really know enough about estrogen / testosterone balance to really agree or disagree. It does seem to make sense though that high estrogen would be a problem regardless of testosterone level.
    I'm not concerned about gyno because I had the glands removed so it isn't a possibility anymore, but I know that high estrogen is bad for many other reasons.

  12. #12
    mesophyte is offline Junior Member
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    Increased my dose to 0.25mg of anastrozole per day. Waited a week. Got tested again and my E2 is at 256pg/mL

    wtf?

  13. #13
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    Sounds like your ai is fake

  14. #14
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    RangerDanger830 is offline Knowledgeable Member
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    Quote Originally Posted by EquilibriumZ View Post
    Sounds like your ai is fake
    It is a possibility, I have gotten fake Adex before. I am guessing since your country has a more strict customs policy then the price of stuff like that is probably higher than here in the states. That would make it more likely to be faked if there is more money involved.

  15. #15
    Deal Me In's Avatar
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    How far into the cycle did you have the first set of labs done? Assuming you didn't do it within the first few days I don't see any other explanation other than the ai is fake.

  16. #16
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    A bit more and you will start to ovulate...

  17. #17
    mesophyte is offline Junior Member
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    yes I think I have to accept that this stuff is fake. I just spent a load of money right now buying anastrozole from a local pharmacy (finally in stock) and new PCT meds (don't want to trust my GrowthCompany PCT meds). Surprised they didn't ask for a prescription.
    Last edited by mesophyte; 08-22-2014 at 02:20 PM.

  18. #18
    mesophyte is offline Junior Member
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    So now that I have my extremely expensive and very real anatrozole. What do I do? Should I take a full 1mg pill today to try and get my E2 down asap?

    Then, how much should I take ongoing before getting BW again since my E2 is so high?

    Today I took 0.75mg of my likely fake / underdosed anastrozole by the way. Not sure if I should take that partially into account.

  19. #19
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    Quote Originally Posted by mesophyte
    So now that I have my extremely expensive and very real anatrozole. What do I do? Should I take a full 1mg pill today to try and get my E2 down asap?

    Then, how much should I take ongoing before getting BW again since my E2 is so high?

    Today I took 0.75mg of my likely fake / underdosed anastrozole by the way. Not sure if I should take that partially into account.
    No point taking your fake ai anymore. Just use the expensive one and bw again. As for the dosage, i would stick to the regular .25mg eod

    Btw what country u in?

  20. #20
    mesophyte is offline Junior Member
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    Quote Originally Posted by EquilibriumZ View Post
    No point taking your fake ai anymore. Just use the expensive one and bw again. As for the dosage, i would stick to the regular .25mg eod
    Btw what country u in?
    Brazil

    I took 0.50mg today before seeing your reply.

    Would be great to get some more feedback... is the standard 0.25mg EOD for a man with 256pg/mL really enough?

    The ranges on my blood test indicate that I'm in the range of a woman at the peak of ovulation.

    Reference Values:
    Female - Folicular Phase - 13 to 166 pg/mL
    Ovulatory peak - 86 to 498 pg/mL
    Luteinic Phase - 44 to 211 pg/mL
    Menopausa - up to 55 pg/mL
    Male - up to 43 pg/mL
    Before Puberty - up to 20 pg/mL

  21. #21
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    I believe everyone is different. The reason it's that high it's cause there was no ai from first place (fake). So now if you take it, it's like a sudden change

    If i were u i d still take the 0.25 eod and bw if that wasnt enough, i d boost it depending on the new value

    Or if you really want 0.5 eod then bloodtest and change.

    Your choice, eitherway u ll need the bloodtest again

  22. #22
    Mr.BB's Avatar
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    Now, what you need is to lower e2 value fast because such high values are bad for you. High estrogen levels in men can double the risk of stroke and increase the risk of cardiovascular disease and heart attacks, of course gyno and erectile disfunction will be other milder side effects.

    No one will tell you the specific value that is the best for you, because everyone is diferent.
    Some people take 1mg ed on cycle, for some 0,25 eod is enough, only blood work will tell whats the best value for you.

    I upped to 0,5mg eod my arimidex which made my e2 value show 22, and was happy about it (it was @ 54 on mid cycle BW). If I was in your situation I would probably take 1mg ed for 3 days and then 0,5ed till blood work, but like I said everyone is different, you need to adjust it yourself.

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