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Thread: Arimidex Dosage

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    timzanemuscle's Avatar
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    Arimidex Dosage

    I'm doing 500mg Test C a week with .5mg Arimidex a day. I'm still feeling a little nipple sensitivity. Is it normal for those that are sensitive to aromatization to do 1mg a day? It seems like a high dose to me from what I read. I know it should start working in a day and I've been taking the Adex daily for a week or so. I don't want to crash test but also don't want to risk gyno. I am in week 2 and have 4 weeks to get bloods drawn.

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    .5mg of adex a day is a ton. Your estro must be low at that dose. The nipple sensitivity might be in your head. Most guys will run .25 every other day. You can run a low dose of nolva if your worried

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    Yeah I'm doing 10 mg of Nolva for a few days now. Will gyno develop through mere sensitivity, or when it's painful that's when I should worry?

    BTW, I'm a guy who was on 210 mg of Test C running it solo for the first time ever and was experiencing pain in nipples.

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    I'm not experiencing any of the fatigue of high dosages of Adex either...

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    Quote Originally Posted by timzanemuscle View Post
    I'm not experiencing any of the fatigue of high dosages of Adex either...

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    Is it pharmaceutical grade arimidex ? From a legitimate pharmacy? Sounds off mate that is a ton of arimidex.

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    Monster Labs. Never read anything bad about them.

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    I’m definitely E sensitive so when I run my first cycle I’ll probably be using .5 eod

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    You may have some underdosed adex. Gyno is lumps or puffyness of nipples. “Tingling” isnt gyno. Its probably just your body reacting to the hormone adjustment. However gyno is not black and white. Let us know what the bloodwork shows

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    The truth about AI dosages is that it can vary greatly from person to person. However, it is very common for people to overdo it because they're guessing instead of getting blood work done. A good friend of mine takes 1mg Adex DAILY as prescribed by his doctor based on his blood work. He's currently running 500mg test, 450 tren , 75 proviron btw (to put it into context).

    Now, if he were to come on here and ask if he's doing the right thing he would get inundated with people telling him his dose is way too high. And tbh, until recently, I would have been one of those people. EVERY single human body is different, and to what extent varies, but none of this is "one size fits all."

    Having said that let's focus on your issue. You're clearly estrogen sensitive so you'll want to start your AI a solid week before you start your cycle so your serum levels won't get too high once the test kicks in (for future ref). One would think since it's cyp that you have a few weeks before you need to worry about estrogen sides but, contrary to popular belief, our levels are supraphysiological the day after a shot of cyp or enanthate ....It just doesn't build up to it's max level until approx 3 weeks..If you're estrogen sensitive it won't take long before enough test has detached from the ester to cause probs.

    What I would suggest to do right now is up your nolva to 40mg ed, do not increase your Adex YET as you don't want to crash your e2.

    Go get blood work done immediately. Everything else you do after increasing your nolva will be based on that! You're increasing the nolva to prevent any further aromatization to occur, because itchiness IS an indication that gyno is forming.....even if it's slight, over time it will become noticeable so it's important to stop it in its tracks.

    Would be cool if you updated us after blood work cause we can learn from this. I'd really like to see where your e2 is and how much Adex you'll need to suppress it.

    (Check this out too pretty interesting)

    Pharmacodynamics
    Effect on Estradiol: Mean serum concentrations of estradiol were
    evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10
    mg
    of arimidex in postmenopausal women with advanced breast cancer.
    Clinically significant suppression of serum estradiol was seen with
    all doses. Doses of 1 mg and higher resulted in suppression of mean
    serum concentrations of estradiol to the lower limit of detection
    (3.7
    pmol/L).
    >The recommended daily dose, ARIMIDEX 1 mg, reduced estradiol by
    approximately 70%
    >within 24 hours and by approximately 80% after 14 days of daily
    dosing. Suppression of
    >serum estradiol was maintained for up to 6 days after cessation of
    daily dosing with ARIMIDEX 1 mg.

    * to clarify, Nolva does not stop aromatization but rather blocks the estrogen from binding. So you can't crash your e2 from taking Nolva which is why you should up the nolva and leave the Adex alone until a doc tells you otherwise
    Last edited by AlphaMindz; 07-11-2018 at 03:29 PM.

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    Quote Originally Posted by AlphaMindz View Post
    The truth about AI dosages is that it can vary greatly from person to person. However, it is very common for people to overdo it because they're guessing instead of getting blood work done. A good friend of mine takes 1mg Adex DAILY as prescribed by his doctor based on his blood work. He's currently running 500mg test, 450 tren , 75 proviron btw (to put it into context).

    Now, if he were to come on here and ask if he's doing the right thing he would get inundated with people telling him his dose is way too high. And tbh, until recently, I would have been one of those people. EVERY single human body is different, and to what extent varies, but none of this is "one size fits all."

    Having said that let's focus on your issue. You're clearly estrogen sensitive so you'll want to start your AI a solid week before you start your cycle so your serum levels won't get too high once the test kicks in (for future ref). One would think since it's cyp that you have a few weeks before you need to worry about estrogen sides but, contrary to popular belief, our levels are supraphysiological the day after a shot of cyp or enanthate ....It just doesn't build up to it's max level until approx 3 weeks..If you're estrogen sensitive it won't take long before enough test has detached from the ester to cause probs.

    What I would suggest to do right now is up your nolva to 40mg ed, do not increase your Adex YET as you don't want to crash your e2.

    Go get blood work done immediately. Everything else you do after increasing your nolva will be based on that! You're increasing the nolva to prevent any further aromatization to occur, because itchiness IS an indication that gyno is forming.....even if it's slight, over time it will become noticeable so it's important to stop it in its tracks.

    Would be cool if you updated us after blood work cause we can learn from this. I'd really like to see where your e2 is and how much Adex you'll need to suppress it.

    (Check this out too pretty interesting)

    Pharmacodynamics
    Effect on Estradiol: Mean serum concentrations of estradiol were
    evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10
    mg
    of arimidex in postmenopausal women with advanced breast cancer.
    Clinically significant suppression of serum estradiol was seen with
    all doses. Doses of 1 mg and higher resulted in suppression of mean
    serum concentrations of estradiol to the lower limit of detection
    (3.7
    pmol/L).
    >The recommended daily dose, ARIMIDEX 1 mg, reduced estradiol by
    approximately 70%
    >within 24 hours and by approximately 80% after 14 days of daily
    dosing. Suppression of
    >serum estradiol was maintained for up to 6 days after cessation of
    daily dosing with ARIMIDEX 1 mg.

    * to clarify, Nolva does not stop aromatization but rather blocks the estrogen from binding. So you can't crash your e2 from taking Nolva which is why you should up the nolva and leave the Adex alone until a doc tells you otherwise
    Exactly ... AI dosage and the body isn’t black and white . Different people are more sensitive to E the. Others which requires more Ana.
    And people need to consider some using certain compounds like mast for example , it actually lowers E while dbol raises E so in short ....

    -always get blood work
    -always have AI on hand
    -always do your Hw on the compounds you use.

  11. #11
    timzanemuscle's Avatar
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    Do the feeling I get in my notes isn't constant. Does that mean anything?

    You said get bloods now. Obviously my blood levels will be higher in a few more weeks, so should I do it now just to measure E2? What would that do for me if I need to get the bloods done at 6 weeks anyway? Thanks for the help.
    Quote Originally Posted by AlphaMindz View Post
    The truth about AI dosages is that it can vary greatly from person to person. However, it is very common for people to overdo it because they're guessing instead of getting blood work done. A good friend of mine takes 1mg Adex DAILY as prescribed by his doctor based on his blood work. He's currently running 500mg test, 450 tren , 75 proviron btw (to put it into context).

    Now, if he were to come on here and ask if he's doing the right thing he would get inundated with people telling him his dose is way too high. And tbh, until recently, I would have been one of those people. EVERY single human body is different, and to what extent varies, but none of this is "one size fits all."

    Having said that let's focus on your issue. You're clearly estrogen sensitive so you'll want to start your AI a solid week before you start your cycle so your serum levels won't get too high once the test kicks in (for future ref). One would think since it's cyp that you have a few weeks before you need to worry about estrogen sides but, contrary to popular belief, our levels are supraphysiological the day after a shot of cyp or enanthate ....It just doesn't build up to it's max level until approx 3 weeks..If you're estrogen sensitive it won't take long before enough test has detached from the ester to cause probs.

    What I would suggest to do right now is up your nolva to 40mg ed, do not increase your Adex YET as you don't want to crash your e2.

    Go get blood work done immediately. Everything else you do after increasing your nolva will be based on that! You're increasing the nolva to prevent any further aromatization to occur, because itchiness IS an indication that gyno is forming.....even if it's slight, over time it will become noticeable so it's important to stop it in its tracks.

    Would be cool if you updated us after blood work cause we can learn from this. I'd really like to see where your e2 is and how much Adex you'll need to suppress it.

    (Check this out too pretty interesting)

    Pharmacodynamics
    Effect on Estradiol: Mean serum concentrations of estradiol were
    evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10
    mg
    of arimidex in postmenopausal women with advanced breast cancer.
    Clinically significant suppression of serum estradiol was seen with
    all doses. Doses of 1 mg and higher resulted in suppression of mean
    serum concentrations of estradiol to the lower limit of detection
    (3.7
    pmol/L).
    >The recommended daily dose, ARIMIDEX 1 mg, reduced estradiol by
    approximately 70%
    >within 24 hours and by approximately 80% after 14 days of daily
    dosing. Suppression of
    >serum estradiol was maintained for up to 6 days after cessation of
    daily dosing with ARIMIDEX 1 mg.

    * to clarify, Nolva does not stop aromatization but rather blocks the estrogen from binding. So you can't crash your e2 from taking Nolva which is why you should up the nolva and leave the Adex alone until a doc tells you otherwise
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  12. #12
    timzanemuscle's Avatar
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    Above first sentence was supposed to be: the feeling I get in my nipples isn't constant. Does that mean anything?

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