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Thread: Can proviron crash E2?

  1. #1
    Dgs59's Avatar
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    Question Can proviron crash E2?

    I started using proviron a week ago, started very low to see how it reacts on me (25mg ED) it's difficult to tell at the moment but I have been grumpy as shit and angry since I started using proviron and it's not passionate angry which helps me train harder but it's grumpy angry and really get a feeling exactly like what I get when my E2 is crashed.

    I will be doing BW this month again but can proviron cause E2 to crash only at 25mg a day? I am on 200mg Test EW.
    Last edited by Dgs59; 08-04-2020 at 11:15 PM.

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    Iíve been on 50 mg ED for 6 weeks, at my last TRT blood test (3 weeks ago) my E2 was on point, right in the middle where it should be. Anecdotally I would say no and cannot think of a reason that it would. My free test was through the roof which is exactly what Proviron should be doing...

    The grumpiness could be a result of increased total and free testosterone
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    Quote Originally Posted by SampsonandDelilah View Post
    I’ve been on 50 mg ED for 6 weeks, at my last TRT blood test (3 weeks ago) my E2 was on point, right in the middle where it should be. Anecdotally I would say no and cannot think of a reason that it would. My free test was through the roof which is exactly what Proviron should be doing...

    The grumpiness could be a result of increased total and free testosterone
    Agree... That could be the reason.

    The reason I was saying crashed E2 because I read that

    Proviron has an affinity for the aromatase enzyme, which is the enzyme in the body that binds with testosterone and converts it to estrogen. When Proviron binds to the enzyme, it blocks testosterone from binding, therefore reducing the amount of estrogen produced.
    Probably misunderstanding it

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    Perhaps your DHT is too high?
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    Quote Originally Posted by Quester View Post
    Perhaps your DHT is too high?
    I don't have baldness and have tons of free test but I can definitely get it checked. My last BW was as follows

    DHEA Sulphate 7.4 umol/L (2.4 - 11.6)
    Testosterone 57.4 nmol/L (10 - 35)
    SHBG 16 nmol/L (10 - 70)
    Free Testo 1954 pmol/L (225 - 725)

    Cortisol 189 nmol/L (150 - 600) (AM)

    FSH < 1 U/L (< 9)
    LH < 1 U/L ( < 8)
    Oestradiol 307 pmol/L (< 100)
    Progesterone 1 nmol/L
    Prolectin 140 mU/L (< 330)
    Last edited by Dgs59; 08-06-2020 at 05:09 PM.

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    Test for DHT on your next BW. High DHT could be behind the psychological aspects of the issues you spoke of above.
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    Quote Originally Posted by Quester View Post
    Test for DHT on your next BW. High DHT could be behind the psychological aspects of the issues you spoke of above.
    Will definitely get it checked, cheers

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