Blood pressure on gear

[vic1778]

My blood pressure is normal, but as soon as I take 100 mg of Testosterone cypionate , after 10 days my blood pressure goes up 160/90 is off and on. I also put on 7 lbs of water in the 10 days. It seems like it makes me retain water, which will raise my blood pressure. I’ve been on 100 mgs for years with no issues. I am now approaching 60 years old. Anybody else experiencing this. I am not taking it for muscle gains, but only to keep my test levels up. Any suggestions? My salt intake is very low also.

[Cuz]

Its estrogen more than likely being converted from the testosterone by your body. Sounds like you are very E sensitive, might wanna check your bloodwork and see if your estrogen is high which it probably is making u retain the water thus elevating your bp

[vic1778]

Will do, thank you

[SampsonandDelilah]

Its estrogen more than likely being converted from the testosterone by your body. Sounds like you are very E sensitive, might wanna check your bloodwork and see if your estrogen is high which it probably is making u retain the water thus elevating your bp

Solid advice.

[vic1778]

My Estradiol pg / ml value 53.5. It’s really high.

[vic1778]

My Estradiol pg / ml value 53.5. , under 30 is a good number.

[teedoff]

My Estradiol pg / ml value 53.5. It’s really

That's a little on the high side. But not crazy. Maybe you're predisposed for high bp?

[wellshii]

My Estradiol pg / ml value 53.5. It’s really high.

Thats not too high.
And you said you have been on test for 20 years at this dose?
So what exactly changed?
What have your levels been before?

[vic1778]

Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.

[Honkey_Kong]

My blood pressure is normal, but as soon as I take 100 mg of Testosterone cypionate, after 10 days my blood pressure goes up 160/90 is off and on. I also put on 7 lbs of water in the 10 days. It seems like it makes me retain water, which will raise my blood pressure. I’ve been on 100 mgs for over 20 years with no issues. I am now approaching 60 years old. Anybody else experiencing this. I am not taking it for muscle gains, but only to keep my test levels up. Any suggestions? My salt intake is very low also.

So you'been on 100mg of test cypionate for 20 years, but if you inject 100mg of test cypionate your BP goes up? Is that 100mg in addition to the 100 you're already taking?

One thing I would suggest you do is split that 100mg of test up in to two 50mg shots per week. That way it's not such a spike every time you take your medicine and more of it will be bound by your SHBG. That alone will let your body regulate it better. I'm not going to say for sure that your high BP and bloating will entirely go away, but it'll likely be reduced.

[scotty51312]

Are you running an AI? Also try taking a baby asprin every day as a mild blood thinner

[s1nc1ty]

I only tryed test once and i was on a low dose of 250mg test enthate per week and i had constant 150 - 160 blood pressure. Didnt go back to down to norm until 3 or 4 months after the cycle

[vic1778]

Yes, I have the same numbers being on in 100 mgs per week. I got off it until I get this figured out. High Blood pressure is a silent killer.

[vic1778]

Yes, I am doing the baby aspirin everyday.

[Honkey_Kong]

Did your doctor order a complete blood count blood test? If so what was your RBC?

[Cuz]

How long has the elevated BP been a problem? You’re estradiol reading is close to normal if its in fact 53. That would lead me to believe you have something else going on sounds to me like its a sign of kidney malfunction

[powerliftmike]

Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.

Are you saying your BP is normal when you are hypogonadal/androgen deficit and then when corrected with TRT it explodes higher? You have been on TRT 20 years without problems and suddenly cannot continue without hypertension? Have you stopped TRT in the past and seen a sudden fluid loss or BP improvement (or hypotension)? Are you ok on 75mg/wk? Post up bloodwork including E2, total test, and % free T. Do you have old bloodwork when things were normal?

[vic1778]

Went to a kidney doctor, did all the testing. My Egfr IS 78, My kidney doctor was ok with those numbers.

[vic1778]

I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone / Total, SM ng/dl = 1050.

[Honkey_Kong]

Went to a kidney doctor, did all the testing. My Egfr IS 78, My kidney doctor was ok with those numbers.

If your Egfr was 78, why would you see a nephrologist in the first place?

[vic1778]

I was trying to rule out everything

[almostgone]

If you've been treated for hypertension for years, it may be time for for a tweak in your BP meds. Personally, I don't like Valsartan, but I do well with Atacand/ Candesartan.

For one thing, you could lower your dose of T if your serum value is 1050 ng/dL....at least on a trial basis. Make sure to split the dosage into 2 injections per week.

One other thought, I didn't do well with Spironolactone. It seemed to lose effectiveness. Maxzide (Triameterene/HCTZ) did me much better.


I've had readjust some of my meds over the years. Will be 59 this year.

Edit: I know you watch your sodium intake, but watch out for hidden sodium in processed food. The bastards will really load up processed foods.

Out of curiosity, how active are you? Any significant physical activity, cardio, etc?

[almostgone]

Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.

Go Easy on the anastrozole. Start low and work up, it is very effective.

[Honkey_Kong]

I was trying to rule out everything

It's pretty difficult to get an appointment with a nephrologist. I had to wait several months before I could see the one I'm seeing and it's several months in between appointments.

Usually, you have a problem that's beyond your PCP's ability to treat it, so he gives you a referral to a specialist (I think most insurance companies require this). I highly doubt just having high blood pressure would be enough reason to see a nephrologist. Especially when your Egfr is in the high 70's.

So you don't have any other conditions that would cause you to need to see a nephrologist?

[vic1778]

No other condition that I am aware of. My primary doctor suggested it based on my egfr numbers. My primary doctor said I had stage 3 kidney disease. My Nephrologist told me my primary doctor don’t know what they were talking about. My Nephrologist did their our series of tests on me, 24 hour urine sample, etc. All my tests came back fine. I have really good insurance. I don’t need a referral to see a specialist. I got in within 4 weeks of my appointment.

[vic1778]

Doctor told me to take 1mg every other day.

[956Vette]

Doctor told me to take 1mg every other day.

1mg arimidex ? Gonna get rekt on that, watch out.

[Honkey_Kong]

No other condition that I am aware of. My primary doctor suggested it based on my egfr numbers. My primary doctor said I had stage 3 kidney disease. My Nephrologist told me my primary doctor don’t know what they were talking about. My Nephrologist did their our series of tests on me, 24 hour urine sample, etc. All my tests came back fine. I have really good insurance. I don’t need a referral to see a specialist. I got in within 4 weeks of my appointment.

Did your primary doctor go to medical school? No PCP practicing in America is going to call an egfr of 78 stage 3.

[Cuz]

Doctor told me to take 1mg every other day.

You’re “dr” doesn’t know wtf he is talking about. Im done with this thread. Best of luck

[almostgone]

1mg arimidex? Gonna get rekt on that, watch out.

X2. Way too aggressive.

[almostgone]

Did your primary doctor go to medical school? No PCP practicing in America is going to call an egfr of 78 stage 3.

Exactly. Most docs will congratulate you.

[almostgone]

I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone/ Total, SM ng/dl = 1050.

I still don't know why you don't try lowering your dose to see if it helps. Your serum T is 1050 ng/dL. Was that taken on a trough day? What is your free T value?

Things just aren't adding up here.

[powerliftmike]

I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone/ Total, SM ng/dl = 1050.

Estradiol in the 50s is high, see if can't get that down a bit. You do realize Spironolactone is an anti-androgen drug (AR antagonist)? You might be able to drop that and simultaneously lower your T to something < 100mg/wk and be ok. While ref ranges are assay specific, generally 1050 ng/dL is much more than is needed; that was 2x 50mg each 100mg/wk total test cypionate ? That is kind of impressive to have that high a level with so little T.

Honestly lowering your T dosage and dropping sprionolactone might resolve hypertension and E2 issues [which are interrelated] with no other intervention, e.g. arimidex , etc.

[vic1778]

Maybe 1 3x’s a week ?

[Honkey_Kong]

You’re “dr” doesn’t know wtf he is talking about. Im done with this thread. Best of luck

I'm with you on this. I'm done playing with the troll.

[Test Monsterone]

Take a lower trt dose. I had to come off trt to regain fertility and my blood pressure reduced enough that I would get dizzy a lot and had to cut my bp meds in half. Also, you’ll feel fine. You could take 50 mg/week and probably feel better than you are now.