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An honest journey

Day 2 - exploring Ketotifen

Rating: 3 votes, 4.33 average.
by , 07-23-2013 at 07:24 AM (1954 Views)
Good day reader,

Today I was up at 05.36 to do my 40 min cardio session and I did feel extra tired. I can not for sure say this is due to the Ketotifen I took the day before or simply the more intense workouts I am doing. I am thinking more workouts than Ketotifen but we shall see. Back in the gym at 11.30 for Legs day. This one always gives me workout pains the next day which I think is a good thing. When I leave the gym after leg day I can hardly walk as I have truly pushed every last bit I can. Diet is going well and this adjusted calorie intake is not a problem thus far. I would be surprised if I had a problem on day 2, let's see what I say on day 30.

I was exploring the effects of Ketotifen a bit more and found and exciting article written on a competing website which would be too good to let go.

What Is It?
Ketotifen is very safe antihistamine used extensively in Europe to treat bronchial asthma and allergies. It is also being studied as a treatment for colitis. When used for asthma, weight gain and an increase in appetite are among the most frequent side effects. Ketotifen also protects the cells in the stomach, small intestine and perhaps the rest of the gut from a number of toxins. A number of case studies suggest that it may be helpful treating skin problems such as acne. Ketotifen also reduces edema (swelling and puffiness caused by water retention) around sores.

Ketotifen Studies
German researchers have published data showing that ketotifen lowers tnf-alpha in the test tube. One study used ketotifen in combination with oxymethadone, a steroid like Megace that helps people gain weight, so it is hard to gauge what effect ketotifen had (the study notes a 14% reduction in TNF-alpha levels and weight gains of 11-12 pounds in less than four weeks). A larger placebo controlled study of this combination is underway. The other study used ketotifen by itself in eight patients with elevated TNF-alpha, (but no wasting). Taking ketotifen for 12 weeks, these patients gained an average of six pounds, had increases in their body cell mass and reductions in their TNF-alpha levels.

Side Effects and Toxicity
Ketotifen is virtually non-toxic (although it is not advised for patients with epilepsy). People who took twenty times the recommended dose (in suicide attempts) suffered no serious consequences (other than embarrassment). Its primary side effects seem to be temporary drowsiness, dry mouth,(and other mucuos membranes) appetite stimulation and weight gain.

Dosing and side effects
No studies have been done to find the most effective dose but the German researchers used 4 mg ED. Dan Duchaine (who discovered ketos use for BB) suggested 10mg ED but in my experience this much is not needed and makes u far too sleepy. I find that 3-4mg ED seems ideal. However, much higher doses have been shown to be quite safe with no adverse affects other than increased drowsiness and appetite – it will make u hungry for solid foods. You can take it divided in the day or all at once.

Ketotifen and Clenbuterol
Clenbuterol is a beta 2 agonist which has a limited anabolic effect during its first few days of use and afterward is normally used to fight fat. At higher doses, however, it can be catabolic to muscle and it must be cycled on a 2 week on, 2 week of basis or the beta 2 receptors that clenbuterol binds to become saturated and down regulate.

Ketotifen’s magic is that it upregulates the beta-receptors including the beta 2s that clenbuterol uses. As long as you are taking ketotifen, it will continue to clean these receptors, never allowing them to downregulate – even while on a heavy clenbuterol cycle. That means you can continue to take clenbuterol indefinitely without having to cycle off to regenerate the receptors. 2-3mg ED can upregulate even severely shut down receptors within a week.

It also means that you don’t need as much clenbuterol to get the same benefits. It seems u can take about 30-40% less clenbuterol and it be equally effective. It also increases the number of receptor sites on the surface of the cell, allowing more clenbuterol to attach and perhaps this is the reason for the increased efficacy. Ketotifen also seems to lessen the sides of clenbuterol including the jitters.
I am overall feeling awesome about my new direction and hope to keep it up.

One more rep!
~T

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