Selegiline also L-Deprenyl

[steroid.com 1]

Probably one of the most important anti-aging medicines a person can take in my opinion. My TRT Doc added this compound to my DHEA/Pregnenolone cream and I can tell you first hand the huge positive affect it has on me. Mild feelings of a wonderful uphoria (just feel damn good all the time), biig increase in libido and neuro protection.

Deprenyl reduces the age-related decline of dopamine, increasing its availability to preserve youthful brain activity

Deprenyl was originally developed as a ‘psychic energizer’, designed to integrate some amphetamine-like brain effects with anti-depressant effects. It has since been shown to protect nerve cells against a wide, and growing, number of neurotoxins, and has been shown to be a neuroprotection/neurorescue agent when nerve cells are exposed to damaging or stressful conditions.


Extending life-expectancy

Professor Joseph Knoll proved that Deprenyl improves the availability of dopamine, slows its age-related decline and helps maintain healthy brain cells by acting as a selective MAO-B inhibitor.

Professor Knoll emphasized that the nigrostriatal tract, the tiny DA-using nerve cluster in the basal ganglia (‘old brain’), typically dies off at an average rate of 13% per decade starting around age 45 in humans. This fact sets the human lifespan at about 115 years, since by that age the nigral neuron population would have dropped below 10% of its original number, at which time death ensues even if in all other respects the organism were healthy.

Therefore, human longevity is in-part governed by the rate of dopamine decline. Its support and enhancement means not only longer life, but lucid mental capabilities too. In fact, four different rat studies and one dog study have shown Deprenyl to be an effective life-extension agent.

Based on the sum total of research, Knoll has suggested that if Deprenyl were used from the 40s on, and only modestly lowered the nigrostriatal neuron death rate – say, from 13% to 10% per decade – then the average human lifespan might increase by 15 years.

Other uses

Deprenyl has become a standard treatment for Parkinson’s disease, and thanks to its aphrodisiac effects, helps to improve sexual function and desire (much more so for men than woman) and I can atest to the fact that it does increase libido...wonderfully so

Conditions for which Deprenyl appears to be therapeutic or ameliorative include: cerebral infarction (stroke), hormone inadequacy, amyotrophic lateralizing sclerosis (lou gherig's disease), fatigue, chronic pain, gastric ulcers, senile dementia, sexual dysfunction, multiple sclerosis, learning difficulties, blepharospasm, hypertension depression and cancer.

Dr. Clyde Reynolds, a clinician who specializes in the metabolic therapy of cancer in Washington State, discovered that cancer patients invariably have imbalances of the neurotransmitters, epinephrine, norepinephrine and serotonin. Dr. Reynolds has found that Deprenyl is highly effective in restoring the normal levels and normal balance of these neurotransmitters. He believes that normalization of the balance of these neurotransmitters is an absolute necessity for the effective treatment of all cancers.

Dosage:
Parkinson and Alzheimer's disease patients are often treated with very high doses of 20mg daily (usually along with other drugs). Anti-aging doses (dependant on age and condition) are more likely to be 2.5mg to 5mg once, twice or three times a week, or, 1mg to 3mg per day, with regular breaks.

Deprenyl tablets are selegiline hydrochloride, which is deprenyl bonded to an in-organic molecule. However, liquid deprenyl citrate (LDC) is selegiline bonded to an organic molecule, one reason why the liquid deprenyl citrate is considered to be superior. This form is generally recognized as the most pure and potent form of deprenyl available. It also allows precise titration for anti-aging purposes, as each ml drop in the bottle is equivalent to 1mg deprenyl citrate - 1mg two times a week for 30 to 35 years olds up to 10mg daily for 80 year olds plus. Ward Dean, M.D., recommends reducing deprenyl doses after several months to lower levels and taking occasional sabbaticals.

After reading this...tell me you're not interested in trying it. I love the stuff and I told this to my Doctor directly and he just smiled and "yes, I do as well" with a wink.

This compound can be bought online without a script. Just Google either Seleginine or Deprenyl and you will find a number of outlets. Or, just ask your Doc (if you're Doc is in the know) to get it compounded for you. Not expensive and the upsides are simply fantastic.

Age. Dosage

30-35 1 mg twice a week
35-40 1 mg every other day
40-45 1 mg every day
45-50 2 mg every day
50-55 3 mg every day
55-60 4 mg every day
60-65 5 mg every day
65-70 6 mg every day
70-75 8 mg every day
75-80 9 mg every day
80 plus 10mg every day

Highly recommend my dear friends

[bass]

GD you are da man! i will ask my clinic about it. is it expensive? off to reading the rest!

[bass]

i read the rest and my question above was answered! thanks again GD!

[kelkel]

GD if this is compounded what are the strengths of all three?

[zaggahamma]

is it also available without rx like dhea/preg?

[steroid.com 1]

GD if this is compounded what are the strengths of all three?

bass - not expensive at all but what it provides in return is fantastic in my book. It's great with a TRT protocol.

kel - 10 mg of DHEA/10 mg of pregnenolone/3 mg of Selegiline all in a gel base administer in the morning. You can feel it all day.

If you don't like feeling horny most of the day, then Selegiline is not for you

[kelkel]

Damn. More stuff to rub on. I see cyp in my future!

[bass]

bass - not expensive at all but what it provides in return is fantastic in my book. It's great with a TRT protocol.

kel - 10 mg of DHEA/10 mg of pregnenolone/3 mg of Selegiline all in a gel base administer in the morning. You can feel it all day.

If you don't like feeling horny most of the day, then Selegiline is not for you

GD, unless i am not looking at the right places this stuff is not cheap! can you PM me your recommendation?

[THINKBIG]

Dumb question but how is this administered? and where? Never used any topical gels. Sounds worth looking into Thanks...

[sirupate]

Thanks gdevine. What you posted is what I was hoping for. I think selegiline is available from pharmacies outside of the US. It may be available as a vet med...but not sure. I'll give it a try at some point for the libido boost alone, but the other potential benefits sound great too.

[steroid.com 1]

Administered as a gel on the inside of forearms.

Can be bought online from overseas pharmas or of course from your Doctor.

[kelkel]

I just checked with a local compounding pharmacy. Said just bring a script, they can do it. Just have to bill insurance myself.

[lvs]

GD, unless i am not looking at the right places this stuff is not cheap! can you PM me your recommendation?

First post, been lurking for a while and learning lots. finding this topic interesting and also finding the same thing bass did. If anyone would be so kind as to PM any information about where to get this, thanks in advance. GD, have you tried the tablets, seems to be more cost effective.

[steroid.com 1]

First post, been lurking for a while and learning lots. finding this topic interesting and also finding the same thing bass did. If anyone would be so kind as to PM any information about where to get this, thanks in advance. GD, have you tried the tablets, seems to be more cost effective.

You can find Selegiline (Deprenyl) online for doses of 5 mg / day at about a $1.00 / day. Pills are fine but there is a liquid form that has much higher uptake as it enters the bloodstream sublingual and bypasses the liver.

Trust me when I tell you Selegiline is worth every penny IMO.

Ivs, you need 50 posts before we can PM you.

[zaggahamma]

You can find Selegiline (Deprenyl) online for doses of 5 mg / day at about a $1.00 / day. Pills are fine but there is a liquid form that has much higher uptake as it enters the bloodstream sublingual and bypasses the liver.

Trust me when I tell you Selegiline is worth every penny IMO.

Ivs, you need 50 posts before we can PM you.

so your saying that the selgiline are fine in pills but not the dhea/preg? correct?

[lvs]

GD, thanks, I was hoping I wouldn't need 50 to receive, ugh! Can you click on my banner and send an email or do you need 50 for that too?

The liquid form seemed much higher that is why I was asking about the pills, but hate to not be able to bypass the liver.

You can find Selegiline (Deprenyl) online for doses of 5 mg / day at about a $1.00 / day. Pills are fine but there is a liquid form that has much higher uptake as it enters the bloodstream sublingual and bypasses the liver.

Trust me when I tell you Selegiline is worth every penny IMO.

Ivs, you need 50 posts before we can PM you.

[kelkel]

But a cream/gel is the best way to go?

[steroid.com 1]

so your saying that the selgiline are fine in pills but not the dhea/preg? correct?

Yes.

[steroid.com 1]

But a cream/gel is the best way to go?

Especially for Preg/DHEA.

[sirupate]

Just fyi...went looking online and found selegiline tablets for relatively "cheap". Something like $.14 per 5mg tab. Typical dose for me would result in $.07 per day. Not sure how bad they will get me on shipping, but at that price, I'll just buy a year supply to spread the shipping over more tabs. Need to look for the liquid version. I'll report back if I can get selegile successfully and after a trial period.

[zaggahamma]

Just fyi...went looking online and found selegiline tablets for relatively "cheap". Something like $.14 per 5mg tab. Typical dose for me would result in $.07 per day. Not sure how bad they will get me on shipping, but at that price, I'll just buy a year supply to spread the shipping over more tabs. Need to look for the liquid version. I'll report back if I can get selegile successfully and after a trial period.

that would be great thanks

[steroid.com 1]

Liquid:
http://www.biogenesis.co.za/pi-deprenyl.asp

[lvs]

thanks for posting! Okay so feeling rather stupid now. The site shows 12 ml 300mg bottle. Documentation says 1 mg for every ml drop for precise titration. So would that be 12 doses if taking 1 mg per day or 300 doses?

[Titleesq]

Liquid:
http://www.biogenesis.co.za/pi-deprenyl.asp

Purchased from this site Friday afternoon. Website indicates delivery time will be between 1-6 weeks. I believe the shipping originates in South Africa. When I have had a chance to give it a go I will report back with my findings. I also purchased a bottle of Phenylethylamine as this appears to work synergistically with the Deprenyl. Is anyone familiar with Phenylethylamine?

[bass]

Purchased from this site Friday afternoon. Website indicates delivery time will be between 1-6 weeks. I believe the shipping originates in South Africa. When I have had a chance to give it a go I will report back with my findings. I also purchased a bottle of Phenylethylamine as this appears to work synergistically with the Deprenyl. Is anyone familiar with Phenylethylamine?

no familiar with Phenylethylamine. yes please let us know how Deprenyl works for you!

[JD250]

A 20ml/300mg bottle for 70 bucks, I dont understand the dosing either, it says 1ml drop is equal to 1mg......what the hell is a 1ml DROP, I know what 1ml looks like and I know what a drop is but a 1ML DROP??????? do they mean a 1ml dropper full? Thats over 2 bucks a dose!!!

[sirupate]

Made my order of the tabs last night...foreign pharmacy and got a confirmation email this morning. The liquid may well be better, but the cost difference is pretty great too. My tablet doses will come out to around $.10 per day. I expect the selegiline will take 2-3 weeks to arrive at my house. I'll post up after a few weeks of use.

[Fred40]

A 20ml/300mg bottle for 70 bucks, I dont understand the dosing either, it says 1ml drop is equal to 1mg......what the hell is a 1ml DROP, I know what 1ml looks like and I know what a drop is but a 1ML DROP??????? do they mean a 1ml dropper full? Thats over 2 bucks a dose!!!

$85 with shipping. There's 300mg in the bottle.....so if your daily dose is 2mg then you have 150 days worth in one bottle. What I don't get is it's a 20ml/300mg bottle........that's 15mg per ml, not 1mg per ml.

[lvs]

glad it is not just me...

$85 with shipping. There's 300mg in the bottle.....so if your daily dose is 2mg then you have 150 days worth in one bottle. What I don't get is it's a 20ml/300mg bottle........that's 15mg per ml, not 1mg per ml.

[JD250]

I cant make sense of it, it may be a great deal or a deal breaker, not sure.

[Fred40]

From reading it my guess is that 15 drops will = 1ml, therefore 1 drop would = 1mg.

[JD250]

So if you're using 1mg a day that bottle should last all year? Nearly.

[steroid.com 1]

See dosage by age in my original post.

[bass]

i asked my clinic about Deprenyl via email but haven't heard any thing yet!

[JD250]

gdevine......I get that, I should use 1 mg a day what we dont get is the strength/volume/dosage/ mumbo jumbo on the liquid, trying to figure out how many doses are in that bottle for 80-ish dollars.

[Titleesq]

Hey bros. Package arrived this morning. To clear up any confusion regarding dosage and volume of Dep-Pro, it is dosed at 1mg/drop. It is packaged in a small, brown glass container that holds 20ml of liquid. There is a clear pipette with a bulb on the top (used for drawing up the liquid) that twists onto the bottle. Each DROP is equal to 1mg and there are 300 drops per 20ml bottle. I hope that clears up that issue.

Anyway, I just got it today and would imagine that I won't have anything to report for awhile, but when I do, you all will know.

[lvs]

Titleesg, thanks for clearing up the dosing confusion. It really didn't take that long to get did it? I guess you ordered it site wise based on the links posted above?

Hey bros. Package arrived this morning. To clear up any confusion regarding dosage and volume of Dep-Pro, it is dosed at 1mg/drop. It is packaged in a small, brown glass container that holds 20ml of liquid. There is a clear pipette with a bulb on the top (used for drawing up the liquid) that twists onto the bottle. Each DROP is equal to 1mg and there are 300 drops per 20ml bottle. I hope that clears up that issue.

Anyway, I just got it today and would imagine that I won't have anything to report for awhile, but when I do, you all will know.

[Titleesq]

Titleesg, thanks for clearing up the dosing confusion. It really didn't take that long to get did it? I guess you ordered it site wise based on the links posted above?

Order was placed on the afternoon of 9/16 and arrived today 9/28, so just under 2 weeks. Don't want to get hassled for posting a source, but PM is on the way.

[Titleesq]

lvs,

You can't get PMs yet, but you are correct, GD posted a link prior in this thread (I totally forgot). GD is always gtg with his info, and that's the one I went with.

[lvs]

Thanks.

lvs,

You can't get PMs yet, but you are correct, GD posted a link prior in this thread (I totally forgot). GD is always gtg with his info, and that's the one I went with.