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  1. #1
    Jburrin22 is offline New Member
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    Aug 2014
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    Dht high, e2 low, worried about gyno.

    Little history, 36 years old, been on trt for about 5 years.
    Have had gyno for around 15 years from being young and dumb. Finally pulled the trigger and had surgery a little over a week ago. Can't believe i waited this long, now i just need to heal.

    test cyp 200mg/week
    hcg 300units 3x/week
    anastrazole 0.5mg 3x/week

    Anyway this is my latest bloodwork results.
    ENDOCRINE EVALUATION
    FSH 0.2 L 1.5 - 12.4 mIU/ml
    LH <0.100 L 1.7 - 8.6 mIU/ml
    PROLACTIN 12.6 4.1 - 18.4 ng/ml
    PROGESTERONE 0.31 <0.84 ng/mL
    ESTRONE (E1) 15.2 <60 pg/ml.
    ESTRADIOL (E2) <5.00 L 7.6 - 42.6 pg/ml
    DHEA-SULFATE 409.8 88.9 - 427.0 ug/dl
    DIHYDROTESTOSTERONE 66.6 11.2 - 95.5 ng/dl

    TESTOSTERONE , TOTAL 754 280 - 1100 ng/dl
    SEX HORMONE BIND GLOBULIN 41 10 - 80 nmol/L
    TESTOSTERONE, FREE 13.59 1.9 - 27 ng/dl
    BIOAVAILABLE TESTOSTERONE 375.2 62 - 512 ng/dl
    IGF-1 121.0 73 - 218 ng/ml

    So after talking with the Dr. he wants to lower the anastrazole from 3x weekly to 2x weekly. Says the e2 is way too low
    He also feels the DHT is high and i have been having a decent amount of hair loss recently. He recommends using a dht blocker such as saw palmetto, propecia or even avodart.

    I am obviously nervous about the gyno coming back, with lowering the estrogen blocker and then blocking the dht wouldn't that be increasing my chances of the gyno coming back.

    I took saw palmetto and avodart separtely before (while on trt) and they both seemed to make the gyno even worse then it was.

    The surgeon says he removed the majority of the gland but there is always a slim chance it could come back. Impossible to get all of it out. He removed the gland and did lipo as well. So i would prefer to do everything possible to keep the gyno off. Of course i don't want to stop the trt and would prefer to keep my hair if possible. Any suggestions?

    Thanks guys

  2. #2
    hammerheart is offline Knowledgeable Member
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    Your DHT is actually normal and not high.

    DHT is your functional estrogen antagonist, it will balance out the action of the latter on tissue, including nipples.

    I'd advise to only lower arimidex dosage, that alone might dial down DHT levels a bit, if that's a problem.

  3. #3
    Jburrin22 is offline New Member
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    Aug 2014
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    Thanks for the response.
    I was looking over previous bloodwork from 2 years ago when i was off trt for around 6 months.
    Dht was at 19, now it's at 66.
    Wasn't losing any hair then however i felt like shit, hence being back on trt again. Tough getting everything dialed in.
    Thanks for the advice i will try just lowering the anastrazole and see if that helps.
    Would it hurt to try to lower the dht with starting with saw palmetto if the anstrazole dose dropping doesn't do it? How long should i wait. Right now next blood test is in 3 months.

  4. #4
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Like Bizz said, your DHT is fine. If you're prone to hair loss that's another issue, but it's not exacerbated by the numbers your presenting here. Re your adex that dose is ridiculously high. It's actually what I'd run if I were running 750 mgs test per week....

    You would also benefit from splitting your dose in half and injecting twice per week. It may even allow you to reduce your test dose a bit and still maintain great numbers along with reducing T to E conversion. Also dropping your HCG dose to twice per week will help with estrogen as well.
    Last edited by kelkel; 05-01-2017 at 10:11 AM.
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  5. #5
    Jburrin22 is offline New Member
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    Thanks guys for the input. I will pry feel even better with the e2 coming up a little.
    Does the spacing for the adex matter at all and the hcg ?
    I will be splitting the test dose up to monday and thursday instead of just monday. Normally i take the adex and hcg mon, wed, fri. Was going to try Mon and thursday with that as well, but just making sure that doesn't matter.
    Thanks again for your responses, you guys know your stuff. Much appreciated.

  6. #6
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Taking your HCG the same day as test is fine. It's what most do quite honestly. Keeps it simple. Remember, this will be an experiment for you and you'll need BW to master it. I would also take your lowered adex the same day as you inject which helps time the peak of the test injection, which is when you need it most.

    What dose (adex) you start with is up to you but as your current E2 level is crushed I'd consider skipping the adex dose at your next injection and implementing it on the following one. Maybe .25 x 2 per week and retest in 3-4 weeks or so. Private labs are available if you're in the states and don't want to go through your doctor. Surprisingly inexpensive as well.
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