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Thread: IGF-1 Temperature
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06-11-2005, 03:45 PM #1
IGF-1 Temperature
I found this to be very interesting and contrary to what everyone thinks:
Storage, Taken from MR
The stability of a liquid solution of LR3IGF-I was monitored for a period of two years at storage conditions of -20 C, +4 C, +22 C, and +37 C. The final concentration of LR3IGF-I was in acetic acid. At various time points, samples were taken and compared to a lyophilized control (stored at 4 C). Listed below are the stability results for each respective storage condition.
Storage Condition: -20 C (-4 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +4 C (39.2 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +22 C (71.6 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +37 C (98.6 F)
Biological Potency No Change up to 1 year
Immunological Activity No Change up to 1 year
Mobility of Protein No Change up to 1 year
Elution Profile by reversed phased HPLC No Change up to 1 year
In conclusion
There is no significant difference in the potency of LR3IGF-I associated with the storage of the liquid formulation when stored at this range of temperatures. There is no evidence for loss of biological activity at any of the tested temperatures when stored as a liquid product. As you can see IGF can be quite stable for even a year at room temp, but if you want to keep it around for a while stick it into the fridge. So IMO the best way to store LR3 that is suspended in BA is in the freezer. The BA wont allow it to freeze. And if you have it suspended in AA, store it in the fridge.
-MS
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06-11-2005, 03:47 PM #2Associate Member
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well it still is a good idea to keep it cold imo, made further clear by the way mr ships their igf
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06-11-2005, 04:31 PM #3
Yeah, but does that mean these tests are false?
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06-11-2005, 04:55 PM #4Originally Posted by tallyjuice
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06-11-2005, 05:21 PM #5
No, I just have to travel for three days and my IGF will not be refrigerated.
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06-11-2005, 06:58 PM #6
no one?
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06-17-2005, 06:05 PM #7
bump
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06-20-2005, 12:57 PM #8Junior Member
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- Apr 2004
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Those are lab results from Gropep. They are not false but like many I would keep mine in the fridge if I had the choice. If you have no option but to not refrigerate it should be fine anyways.
Hope this helps
-MR
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06-20-2005, 03:40 PM #9
Tally where did you find that? lol it has my initials at the end.....
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