adipotide, Prohibitin-Targeting Peptide 1

[gymfu]

Anyone used this stuff, sounds very promising.

[gymfu]

Maybe the best fat burner ever!

[DanB]

FDA approval for phase I trials

http://www.news-medical.net/news/201...sity-drug.aspx

[gymfu]

Sounds freakn awesome, cuts off the blood supply to fat cells.

[DanB]

do you want to be a guinea pig? but how hard is it to make? i have a strong feeling that this will have same problem as the current generation of myostatin inhibitors, i.e. poor quallity from source , expensive and unknown sides. . . . . but i have to say, id still be tempted if i could source it

[gymfu]

Agreed

[Sgt. Hartman]

Reversal of obesity by targeted ablation of adipose tissue.
Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W.
Source
The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Abstract
Obesity is an increasingly prevalent human condition in developed societies. Despite major progress in the understanding of the molecular mechanisms leading to obesity, no safe and effective treatment has yet been found. Here, we report an antiobesity therapy based on targeted induction of apoptosis in the vasculature of adipose tissue. We used in vivo phage display to isolate a peptide motif (sequence CKGGRAKDC) that homes to white fat vasculature. We show that the CKGGRAKDC peptide associates with prohibitin, a multifunctional membrane protein, and establish prohibitin as a vascular marker of adipose tissue. Targeting a proapoptotic peptide to prohibitin in the adipose vasculature caused ablation of white fat. Resorption of established white adipose tissue and normalization of metabolism resulted in rapid obesity reversal without detectable adverse effects. Because prohibitin is also expressed in blood vessels of human white fat, this work may lead to the development of targeted drugs for treatment of obese patients.

Seems too good to be as simple as they make it seem. They've actually been using it for several years now to shrink cancerous tumors and are just now doing studies on its ability to destroy white fat cells.

[DanB]

If anybody knows of dosing or any logs about it on other boards or even studys where it has been used with aim of destroying fat cells then PM me as Im struggling to find decent info on it

[DanB]

280mcg per kg per day

starting to seem very expensive