Exemestane (Aromasin ) is an aromatase inhibitor, which means that it lowers estrogen production in the body by blocking the aromatase enzyme, the enzyme responsible for estrogen synthesization.

This compound was developed to fight breast cancer in post-menopausal women, who need a particularly aggressive therapy, and for whose first line defenses such as SERMS (Tamoxifen ) have not worked. This should be our first clue in inferring that this compound is pretty strong, or at least stronger than some of the other compounds which are used to fight breast cancer. Exemestane (Aromasin) averages an 85% rate of estrogen suppression, so it’s clearly a very effective agent for bodybuilders and other athletes wanting to avoid estrogen related side effects such as gyno, acne, or water-retention brought on by aromatizing steroids . Specifically, Exemestane (Aromasin) does this by selectively inhibiting aromatase activity in a time-dependent and irreversible manner.

As with most of the compounds in this class, it also causes a reasonable rise in testosterone levels , and as you may have guessed, this rise in testosterone means that Exemestane (Aromasin) can also cause androgenic sides. Exemestane (Aromasin) is very effective at both lowering estrogen (estradiol) and raising testosterone.

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