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Thread: HGH,AAS - increase the number of muscle cells?

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  1. #1
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    Quote Originally Posted by MuscleScience View Post
    Good point!!!!
    There has been speculation if HGH could cause hyperplasmia thrue inhibiting the Myostatin aswell, something like this process:

    If you neutralize myostatin, then the satellite cells would proliferate much longer, substansially increasing the number of myoblast produced. These myoblast would mature into myocits, then into myotubes, and ultimately into new muscle cells.

    What do you think?

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    Quote Originally Posted by vitor View Post
    There has been speculation if HGH could cause hyperplasmia thrue inhibiting the Myostatin aswell, something like this process:

    If you neutralize myostatin, then the satellite cells would proliferate much longer, substansially increasing the number of myoblast produced. These myoblast would mature into myocits, then into myotubes, and ultimately into new muscle cells.

    What do you think?
    I was hoping no one would bring satellite cells up. LOL

    If there is a mechanism this is as good as any. I personally feel that if indeed it does occur that this is the most likely way.

    I have read a few papers about satellite cell being induced to differentiate into new muscle cells. The problem with it is that the literature is real hardcore physiology and they are long and boring to read so I don't like looking at it much.

    But now my interest is sparked, I will probably go through some literature over xmas break when I have time. The journal of applied physiology is were I have seen most of this stuff. If you have ever read one of those papers then you know what I am talking about Victor. LOL

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    Quote Originally Posted by MuscleScience View Post
    But now my interest is sparked, I will probably go through some literature over xmas break when I have time. The journal of applied physiology is were I have seen most of this stuff. If you have ever read one of those papers then you know what I am talking about Victor. LOL
    Yeah I have gone thrue one of those papers. But english is my 2 language, so the literature became to heavy for me to read lol, I didnt understand it properly enough to explain this in detail

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    Quote Originally Posted by vitor View Post
    Yeah I have gone thrue one of those papers. But english is my 2 language, so the literature became to heavy for me to read lol, I didnt understand it properly enough to explain this in detail
    It seemed like you got it well enough to me.

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    Quote Originally Posted by MuscleScience View Post
    I was hoping no one would bring satellite cells up. LOL

    If there is a mechanism this is as good as any. I personally feel that if indeed it does occur that this is the most likely way.

    I have read a few papers about satellite cell being induced to differentiate into new muscle cells. The problem with it is that the literature is real hardcore physiology and they are long and boring to read so I don't like looking at it much.

    But now my interest is sparked, I will probably go through some literature over xmas break when I have time. The journal of applied physiology is were I have seen most of this stuff. If you have ever read one of those papers then you know what I am talking about Victor. LOL
    So this satellite cell/myoblast process is what studies say is hyperplasia?or where it could be happening?Or if it is possible this is the most likely way if it could be explained
    Last edited by IntenseAthlete; 12-02-2007 at 12:33 PM.

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    Quote Originally Posted by Jonnycerious View Post
    So this satellite cell/myoblast process is what studies say is hyperplasia?or where it could be happening?Or if it is possible this is the most likely way if it could be explained
    Yep, that is were most of the interest is centered right now in much of the research. Keep in mind though its not a huge factor in muscle size increase, hypertrophy is still the main and most important way muscles grow in size.

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    Quote Originally Posted by MuscleScience View Post
    Yep, that is were most of the interest is centered right now in much of the research. Keep in mind though its not a huge factor in muscle size increase, hypertrophy is still the main and most important way muscles grow in size.
    So size aside,for an athlete to dope in the off season hoping to acheive things he can recruite later when he is clean or during the season.Is this a more viable egde.In theory?Holding on to 1 or 2% of total performance improvement is podium to not even making the qualifing time.From where Im at its power not weight gain anyway.

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    bump, muscle science, this thread needs a dramatic ending

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