First Cycle .PCT Question.

[BJJ]

I would not run it throughout but keep it on hand just in case.
Some people do not experience testicles shrinkage or they notice a little shrinkage and since it is your first cycle you may want to observe your body's reactions.

You can run it anyway, if using a long ester testosterone, in the two weeks just before your pct.

However, have a look at this thread and make up your mind:
http://forums.steroid.com/showthread.php?t=349581

[Aiwa]

I would not run it throughout but keep it on hand just in case.
Some people do not experience testicles shrinkage or they notice a little shrinkage and since it is your first cycle you may want to observe your body's reactions.

You can run it anyway, if using a long ester testosterone, in the two weeks just before your pct.

However, have a look at this thread and make up your mind:
http://forums.steroid.com/showthread.php?t=349581

Thanks everyone specially BJJ.

I have decided i will wait till i am 25 years to start a cycle, only 2 more years to go.

After marcus300 response about the endocrine system i started to do some more research and shit got a lot more confusing.

Question:

When i am 25 how will i know when my endocrine system is fully matured?

Is then when natural test starts to taper down? , if so what are the common levels for a 25 year old and if these levels correspond to levels when i am 24 or even 26 does this mean i am ready for a cycle?

I guess my question is how do you know when your Endocrine system has matured enough to start cycling?

[BJJ]

Thanks everyone specially BJJ.

I have decided i will wait till i am 25 years to start a cycle, only 2 more years to go.

After marcus300 response about the endocrine system i started to do some more research and shit got a lot more confusing.

Question:

When i am 25 how will i know when my endocrine system is fully matured?

Is then when natural test starts to taper down? , if so what are the common levels for a 25 year old and if these levels correspond to levels when i am 24 or even 26 does this mean i am ready for a cycle?

I guess my question is how do you know when your Endocrine system has matured enough to start cycling?

The only way, presently, is to run a biological age exam which will show you your correct age you are in. Then, you can only guess if your system have fully developed.
For example, I just ran those exams before my Oxandrolone cycle and gladly I was much younger than I am by considering my date of birth.
Unfortunately, those exams are very expensive.
If interested:

The concept of biological age and its relationship with the theories of the ageing:
In recent years, with the recovery of interest to the medical aspects and scientific the basis of the ageing and to the possibility of it through pharmacological interventions targeted, the concept of biological age has become a topic of conversation of great news. Here is that, in relation to the growing sophistication of the application of health, by the man in the road, from the questions: I have some disease hidden? are at risk for some disease? How can I do to remain in good health? It is passed to: what is my biological age? Can I rejuvenating?
The so-called biological age is a concept used frequently but so often vague and improper and with little objectivity to describe a difference between the eligibility of the average life of a cohort of individuals born in the same year and the eligibility of life perceived an individual in the same age. How can establish the biological age of a person? In general the impression immediate derived by the look of the face makes us able to judge if a certain person "is young" or "more old" with respect to its age. According to some authors the perception of the age of a subject or of its features in so apparently automatic, but it is in fact a consequence of the phenomena of learning related to sensory circuits, mental, cinestesici, in addition beliefs, thoughts and emotions. Moreover is common concept that understand the age of a person subject in the face cannot always be easy. Almost inevitably, you must use the use of observations more to less sophisticated indices physiological for which have extensive statistical bases in the general population.
To remove immediately possible misunderstandings must state that at the time has not been defined no standardized method and generally accepted quantify the biological age. Only for certain compartments of the body we currently have a sophisticated diagnostic methods instrumental non-invasive that allow, through the use of specific mathematical models of reference, to determine the biological age.
A typical case is that of biological age skin for which were developed sophisticated techniques based by torquemeter, spectrophotometry and analysis of image of microrelief skin. When instead we refer to biological age in a more global, then there are enormous problems of type methodology. If this quantification proves possible, its use would be unquestionable value, for example to assist the taking of informed decisions on appropriateness of invasive procedures or surgery, with less use criteria of mere subjectivity, or to give the individual a standard that allows him to project in a reliable its quality of life, or even its entitlement to life.
The inability to predict the eligibility of life in the single individual has interfered with the creation of the concept of biological age, even if the term was sometimes used in a subjective, with the complication that a patient seems more old or younger than in his age. The ageing can be regarded as a process multifactorial, which derives from interaction of factors genetic, environmental and living habits. In the course of the time many studies have been sent to the identification of biological events that could be attributable to progressive deterioration that occurs in conjunction with the ageing. Currently, one of more theories credited assumes that there is a common mechanism at the base of many diseases associated with ageing which affect several bodies. This theory is focused on primary role played by free radicals and provides a model plausible and general to explain the process of ageing.
The abstract start from the theory that aging and diseases associated with it are the result of damage caused by phenomenon of oxidative stress. This process is associated with one imbalance between the excessive production of oxidizing factors (such as free radicals) and a decrease in antioxidants defenses, that finally takes the form of damage to the body. According to the most modern theories aging is characterized by a state of chronic inflammation mild linked to genetic predisposition that innate alterations to the genetic heritage acquired by everyone in the course of his life for stochastic reasons and/or environmental.
This type of the inflammatory process can lead, in the long term, to impairment of organs and equipment thus to the reduction of the longevity, increasing the sensitivity to some risk factors. The diseases related to the age, such as Alzheimer’s, Parkinson’s disease, atherosclerosis, the type 2 diabetes, osteoporosis, begin to manifest themselves or be amplified by inflammation. For this reason the study of inflammation, and in particular the alteration in the production of cytokines that govern this process, is a frontier still little explored but very promising.

Estimation techniques of biological age by algorithms mathematical-statistics:
The difficulties involved in the determination of biological age through the examination direct and aims of the subject have urged the search of quantitative techniques to enable it to reach with lowest effort to a similar result, at least from the point of theory. The latter statement is of obligation because, in keeping with thermo-fee, no mathematical model, as sophisticated, substitute for direct observation of reality. Since there is a single method for estimating the biological age, may be useful in the first instance to operate a classification of the main methods available. In principle we can therefore distinguish two possible types of approach:
1) techniques that are trying to estimate, on the basis of some biological characteristics of the individual, the biological age that would be achieved by recourse to a methodology based on direct observation of the subject. These techniques are trying to build an algorithm in a position to imitate the best possible the process of awarding of biological age that would be a human being following a procedure empirical as those consolidated by legal medicine. This kind of techniques, are not generally be accompanied by instruments to test the validity of the standard that try to replicate. Have the problem that, even if it were possible to replicate perfectly the decision-making human allocation of biological age by a mathematical process, if it human fact, the process to be wrong would not be possible realizing it.
2) techniques which imply a definition of the concept of biological age, shall inform mathematics or statistics, in terms of a formal report with other biological characteristics of direct and possibly easy measurement in the individual. Since this report is used as note only in some of its aspects, in accordance with this approach will be first to use the data collected on a large number of individuals to specify the nature of this report, then use the mathematical formula so defined for the allocation of biological age of an individual on the basis of biological characteristics that were considered to be relevant for the purpose of its definition.

The validation of estimation techniques of biological age:
The techniques that are trying to estimate the biological age following the first approach are characterised by minor issues to validation. In fact, just take a group of individuals independent from that that was used for the construction of method validation, estimate for such individuals the biological age and compare it with the "true". Although this method of validation can hide thin pitfalls of a statistical nature, above all that linked to representativeness of the sample of validation and therefore the generalization of the results, it is undoubtedly equipped with an intrinsic and self-evident validity. Also, if properly conducted, allows to acquire information useful to improve the estimation method.
This is not the process of validation for technical of the second type. In this case, in fact, the biological age is directly defined in mathematical terms are looking for optimize a particular criteria with a rational generally explained by its application in which you want to use the estimated age. In such cases, therefore, it is to test the extent to which the algorithm of estimate has been able to optimize the criterion adopted, as its rational taken as valid prior.
The method of validation is very different from previous case since these techniques do not pose the objective to estimate a given that pre-is there to them but are seeking to satisfy the better, on the basis of the reality empirical, a precise criterion for optimality theoretical dictated by specific application for which is built the model. The validation is reduced to see how these techniques are able to extract from the real data an information that may be interpreted in terms of biological age.
As regards the approach of first type, the problem reduces "simply" in the construction of an algorithm able to replicate the performance of a human decision maker on the basis of a sample of individuals that is representative of the population of subject to which it will then apply the algorithm. For each of these individuals, therefore, must be available the biological age attributed by human decision maker and a number of variables within which to choose the most suitable for the construction of a predictive model.
The generalization of the results should be guaranteed, in the statistics, from the application of specific sampling plans based on random mechanisms to prevent, at least in terms probabilistic, to build a model not extensible to persons other than those that entered in the sample. This is therefore not extraneous to the algorithm predictive in itself, for which it is assumed that the representativeness of the sample used for its construction has been suitably ensured by appropriate practice of selection of individuals.
The regression techniques of origin may indeed be accompanied statistical methodologies as neural networks that can see their genesis in many theoretical contexts, more than applications, or hybrid solutions that draw separate from methodological deans but can be properly integrated in the light of their complementarity. A very classic is that of the application to appropriate statistical techniques to support the construction neural models. The framework can be then supplemented by more sophisticated algorithms as the support vector regression, the regression trees, the techniques based on whole populations (ensambles) of models show in place of one, as the bagging or the effect.
The situation is very different and more heterogeneous for the approach of a second type, for which we will just to submit briefly only some experiences we consider particularly representative of this second mode and useful to introduce our algorithm of calculation. A solution well characterized along the lines of second approach is based on observation that the value of the laboratory of many biomarkers tending to decrease in an approximately linear way the advance in age; authors have built a system of determination of biological age based on simple models of linear regression constructed from from the figures in 16 biomarkers.
This technique not only allows to estimate the biological age, but even before it from an implicit definition that follows the particular statistical report identified between age, biological age and value of biomarkers selected, as is characteristic of the approaches of the second type. The study in question has its interest not so much in the use of regression, but in its use in a manner not technically banal and in the construction very glossy of rational on the basis of which is built the model proposed.
The research mentioned above are particularly significant from our point of view, because even in our algorithm of calculation are widely use of models of regression. Also, very important to our eyes is the condition that the biomarkers expressed therein are determined on healthy people for the purpose of construction of the model, as the state of health plays a crucial role in our algorithm. Closely linked to experience structured around the models of regression are different searches based on measures of correlation, since they relate to a similar context and in many cases prodrome to that of regression. Investigations very complex from the point of view of the statistical methodology were based on analysis techniques of the factors and other methodologies from it derived.
In this context, the most famous and sophisticated is Nakamura based in large part on the lisrel methodology, which may be considered a sort of widespread common analysis of factors. In this search is done a survey with a very extensive information on the basis of 9 biomarkers selected by a group of 25, time to clarify the plot of relationships between these measures and the concept of biological age that have not to be limited to its simple quantification, which in reality is not between the declared purposes of work but that may be obtained from the model.

This is the list:

1. D-ROMs (REACTIVE OXYGEN METABOLITES) Test {blood}
2. OXI-Adsorbent Test {blood}
3. EICOSANOIDS Test {blood}
4. ALCAT Test (ANTIGEN LEUKOCYTE CELLULAR ANTIBODY TEST) {blood}
5. DISBIOSI Test {urine}
6. 8-OH-2DG {urine}
7. HOMOCYSTEINE {blood}
8. MELATONIN SULPHATE {urine}
9. Vitamin A Measuring {blood}
10. Vitamin E Measuring {blood}

The testosterone range in males is from 437 to 707 ng/dl. In any case, it may differ from different labs.

[Aiwa]

The only way, presently, is to run a biological age exam which will show you your correct age you are in. Then, you can only guess if your system have fully developed.
For example, I just ran those exams before my Oxandrolone cycle and gladly I was much younger than I am by considering my date of birth.
Unfortunately, those exams are very expensive.
.

Man,this is complex.

So if i am 25yrs i can still only guess if my system is fully developed?

I know the endocrine system deals with the secretion of many hormones that transfer information from one set of cells to another,

What is it that makes for a fully developed/fully functional system, is it the amount of hormones that is secreted .The state/age? of the glands: pituitary gland, hypothalamus, pancreas, thyroid gland,testes etc. ??

Thanks.