Anavar drying out joints like Anavar?? HUH?

[TKO Performance]

Dude, again with this stuff? Winstrol IS 5a-reduced. It doesn't increase DHT in in the body. And you're the only person I've seen claim that Anavar increases progesterone, and that progesterone is some miracle hormone for your joints. Where are you getting this info?

http://www.mesomorphosis.com/article...our-joints.htm

Check out the info and sources if you like.

Winstrol is indeed 5 alpha reduced, as mentioned. However, it still acts as a progesterone antagonist, effectively mimicking the effect free DHT has in the body. The method is different, but the result is the same; decreased progesterone. I was simply never clear on the method, but have since researched further. My apologies for the unintentional dissemination of misinformation.

[Lifeguard102]

I got some "Anavar" my source. I took 80mg/ed for 6 weeks. I got lean but my joints were so sore and stiff I thought I needed knee replacements. From what I'm reading Anavar should never make your joints feel like that? Then it seems I got wrong stuff from my source.

From personal experience anavar can cause tremendous joint pain.
At least it did this to me.
I ran 50 -100 mg ED for 10 weeks.
My summation is if you have inflamation, arthritis, bone spurs, rotator issues etc it finds these areas most appealing to attack . When this happens ouch for FAK SAKES!!!

[TKO Performance]

I've never heard of Anavar causing joint issues. Are you sure it was legit, as noted it's been faked with Winstrol many, many times. The results are similar, but Winstrol typically causes joint pain whereas Anavar is not typically associated with it.

Also, 10 weeks is longer than most would recommend for any oral.

[Necrosaro]

I had issues with Anavar with my bones running the stuff; must depend on the users body

[Bonaparte]

http://www.mesomorphosis.com/article...our-joints.htm

Check out the info and sources if you like.

Winstrol is indeed 5 alpha reduced, as mentioned. However, it still acts as a progesterone antagonist, effectively mimicking the effect free DHT has in the body. The method is different, but the result is the same; decreased progesterone. I was simply never clear on the method, but have since researched further. My apologies for the unintentional dissemination of misinformation.

1) First off, Anthony Roberts is the biggest retard in the world of AAS and has 0 credibility. There is a sticky on this site explaining why.

2) That article is 5 years old, so a lot of things have changed since then (due to more recent studies and findings).

Other than that, yes, I believe that Winstrol does compete for the progesterone receptor, and that this might partially explain why it dries out the joints so bad. However, it doesn't actually lower progesterone, just compete with it at the receptor. And this is still largely speculation and theory based on this pub-med article:
http://www.ncbi.nlm.nih.gov/pubmed/8079819

You also have to take into account that Winny is 5a-reduced and binds tightly at the AR, so it antagonizes estrogen effectively, which will dry out your joints by itself to a degree.

[TKO Performance]

1) First off, Anthony Roberts is the biggest retard in the world of AAS and has 0 credibility. There is a sticky on this site explaining why.

2) That article is 5 years old, so a lot of things have changed since then (due to more recent studies and findings).

Other than that, yes, I believe that Winstrol does compete for the progesterone receptor, and that this might partially explain why it dries out the joints so bad. However, it doesn't actually lower progesterone, just compete with it at the receptor. And this is still largely speculation and theory based on this pub-med article:
http://www.ncbi.nlm.nih.gov/pubmed/8079819

You also have to take into account that Winny is 5a-reduced and binds tightly at the AR, so it antagonizes estrogen effectively, which will dry out your joints by itself to a degree.

Yes, I know no one likes the author, but you have to look deeper than that. I actually took the time to research his sources, and though the author may be a parrot for them; the source material is legitimate. This is evidenced by your link, which if I'm reading right dates back to 1994. It's pretty clear that progesterone modulates actual DNA synthesis relating to collagen synthesis. Until there is some groundbreaking study that shows otherwise I think we can safely assume that modern science is in agreement on that point.

The antagonistic effect on estrogen is also another reason why you can experience joint issues with Winstrol. From what I've read it seems that this effect is also likely progesterone based, but there is not 100% certainty on that at this time.