Dose related as well, I assume?
Would you then compare the situation of clen vs beta blockers to the situation of nolvadex vs estrogen?
Dose related as well, I assume?
Would you then compare the situation of clen vs beta blockers to the situation of nolvadex vs estrogen?
Dose does also have a relation. If you have more of compound X then there is physically more of that compound to occupy the receptors vs that of compound Y.
However compound Y may have an affinity to bind to the receptor that is so strong that compound X may be knocked off the receptor or compound Y may actually occupy that receptor forever. An example of this is that of Carbon Monoxide vs that of Oxygen in the hemoglobin molecule. CO binds at 100,000x stronger to hemoglobin than that of Oxygen. So Oxygen can not bind to the hemoglobin that is already bound up with CO.
A better comparison or example would be histamine H1 vs something like benadryl (Diphenhydramine hydrochloride).
Benadryl binds to the Histamine H1 receptor and blocks completely the action of Histamine and its effects.
Nolvadex is a estrogen mimicing molecule and binds to the ER receptor and causes some but not all of the effects that a regular Estrogen molecule would effect. Thus "selectively" blocking some of the least desired effects. Thus why its classified as a Selective Estrogen Receptor Modulator
Last edited by MuscleScience; 08-27-2010 at 12:00 AM.
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