Your making a habit of being incorrect now aren't your Sworder.
Keep copy, pasting and googling and the cracks will show - and they are.
Banned- Scammer!
Your making a habit of being incorrect now aren't your Sworder.
Keep copy, pasting and googling and the cracks will show - and they are.
"cool as shit and knows his stuff"
This is all serious science stuff and way way over my head here your guys knowledge is far superior than what mine or the average joes will ever be.Originally Posted by Swifto
When it comes to advice on this board there are some heavy hitters I seriously trust down to the final word
Sheven (lab)
Bonaparte (lab)
Swifto (read your original hcg post years ago)
Marcus (probably calmest member ever)
Austinite
Times roman
Lunk
Farfrommassive
And there are others (apologise if not mentioned)
Every once in a while I see members come out of nowhere with masses of advice like sworder and think wow asset to the board.
I've been here a few years now and only chime in when I think I can give a appropriate answer based on my experiences and very very limited knowledge.
Could somebody not get hurt of this copy and paste attitude that some folks have
All in all this board is amazing and full of volumes of information that I am slowly digesting but sometimes I do worry about incorrect advice and theories having a effect on younger members.
Banned- Scammer!
What do you mean?
The copy and pasting is done mostly be repeating others articles and theory's and when they are wrong, so is the copy and paster. Sworder is a member of another board and repeats Michael Scally's and Bill Roberts hard work. It makes him sound intelligent here, but he's written f*ck all himself. I have a fair amount of experience with his type, its nothing new.
NO ONE is always right, we all make mistakes along the line. There are only a select few that havent in my experience on these boards, one of them is no longer alive (Nandi - Karl Hoffman).
ARs TOP DOG ~ MONITOR ~
We got some guys here that are true lab rats.These guys know their stuff.And I really respect their knowledge and love it when they show it off.Now just try to find this somewhere else.
Banned
Contribute instead Swifto! Lets hear about the DHT receptors
Yes, 99% of the things I know are due to Michael Scally MD and Bill Roberts, I will always give them credit for my knowledge base. I haven't written any book nor attended Steroid Pharmacology 101. So...?
I am often wrong in my interpretations of data or in my theories, which I don't mind at all!
The interesting thing about the DHT derivatives is their concentration in different skin regions. If you would measure the metabolic enzyme (3-a hydroxysteroid dehydrogenase) in different areas you might find some interesting data and, it could be an explanation to the steroid induced acne distribution. I will look into this further...
Last edited by Sworder; 10-20-2012 at 12:44 PM.
AR-Hall of Famer
Contribute instead Swifto! Lets hear about the DHT receptors
Yes, 99% of the things I know are due to Michael Scally MD and Bill Roberts, I will always give them credit for my knowledge base. I haven't written any book nor attended Steroid Pharmacology 101. So...?
I am often wrong in my interpretations of data or in my theories, which I don't mind at all!
The interesting thing about the DHT derivatives is their concentration in different skin regions. If you would measure the metabolic enzyme (3-a hydroxysteroid dehydrogenase) in different areas you might find some interesting data and, it could be an explanation to the steroid induced acne distribution. I will look into this further...
http://en.wikipedia.org/wiki/3-beta-HSD
http://www.ncbi.nlm.nih.gov/pubmed/2243100
From what I can find, 3-beta-HSD is mainly responsible for the conversion of all hormonal precursors into more active hormones in the adrenal glands.
What does this have to do with the actions or metabolism of DHT-analogues (5a-reduced steroids)?
Last edited by Bonaparte; 10-20-2012 at 01:59 PM.
Banned
3 Alpha, not beta!
AR-Hall of Famer
Ohhhh, now I see what you're getting at!
This is the enzyme that deactivates DHT in skeletal muscle (where it is concentrated).
But here's the problem: that only affects DHT, not masteron and other DHT derivatives, which were modified specifically to avoid deactivation by 3-a hydroxysteroid dehydrogenase, so that they could remain active in skeletal muscle and thus have have an anabolic effect.
So no...that's not it either. They just cause acne (if highly androgenic), lipolysis, and reduce estrogen because they share some properties of DHT.
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