Just a question I wouldn't have any plans to run something with Anadrol in it lol
Just a question I wouldn't have any plans to run something with Anadrol in it lol
Yeah, it has been done. I've made it myself at 50mg/ml, but it hurt like hell. Dbol makes for a much better injectable bulker.
Just a question. Why would someone want to inject something that works pretty good orally ? Would it affect the body different , be stronger ?
^^^^^^ for starters it would not be as toxic like it is in am oral format.
And liquid adrol really ****s with your stomach too, i felt sick the entire time i was on it
No. That is incorrect. Any drug that enters the circulatory system will eventually pass through the liver. Different routes of administration will change WHEN the drug passes through the liver however.Originally Posted by xjay1234
yes both need to get through the liver but orals are alot more toxic.
Correct.Originally Posted by >Good Luck<
The answer isn't yes or no. There are numerous factors to consider. For a drug to induce its effect, it must be present in appropriate concentrations. Every drug goes through a four step process: Administration, Distribution, Metabolism, Elimination (often abbreviated as "ADME"). The transfer and propulsion (distribution) of a drug through your body is also affected by a number of chemical characteristics (solubility, size of molecules, etc.).Originally Posted by tattoo449
The most common Route of Administration (ROA) is enteral, or what most people call "oral". For many drugs it is the easiest and safest form of injection and (sometimes) the cheapest. Unfortunately, enteral absorption is not always optimal for several possible reasons:
- enzymes in the stomach can deactivate properties of the drug (this is why many drugs are enteric coated to minimize gastric destruction)
- these same enzymes can metabolize the drug early leaving smaller metabolites behind to exert effects
- some drugs will irritate the stomach and promote emesis (nausea/vomiting)
- eating vs. not eating can affect absorption and propulsion of a drug.
Parenteral routes of administration (i.e. injections) will bypass many of the enteral concerns and promote faster absorption and distribution, but have their own risks and and concerns.
See answer above. I tried to keep it as nontechnical as possible. There's more to the pharmacokinetics but I tried to keep the discussion simple.Originally Posted by >Good Luck<
I'm surprised Bonepart hasn't jumped in yet. I'm sure he would add a lot of value to the conversation.
MI, that was your layman's explanation? Lol
Let me try: injecting allows the drug to reach the bloodstream directly. Ingested (oral) drugs need to pass through the liver a first time before reaching the bloodstream. So by injecting a substance, you avoid the first pass through the liver, but it will still pass through the liver a few times later.
So yes, injecting drol reduces toxicity and/or allows for lower doses, since you don't lose any to the liver before ever reaching the bloodstream.
And there you have it...both are liver toxic to a degree but one requires less administered to yeild the same benefits.
Would you say the decreased liver toxicity is substancial enough to go the injection route (not trying to hijack but want to elaborate the topic a bit)
>good luck<
"He who can take advice is sometimes superior to those who give it"
I was holding the fort until you arrived!!!Originally Posted by Bonaparte
Two intense days of discussions with MSKCC and Columbia in NY discussing biochemistry and disease metabolic pathways and I can't get my brain to gear down.
I wasn't wrong though.....I knew you'd be helpful!!!!![]()
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