A. covered it perfectly. The amount of B6 needed is far above a "safe" level and may only have minimum effects controlling prl at best. Let's be honest, most ppl don't control E2 levels properly and some don't use an AI at all. A very small % of those ppl report prl reported issues. The effects of elevated prl are easily reversible and mainly only effect those who do not control their estrogen levels. You can easily save the $ and concentrate on E2 management only pick up some Prami quick if prl becomes an issue.