Did you switch docs Tripper? If your E2 sensitive is 22 you're in great shape and do not need an AI whatsoever. Most of the top guys in the industry like Crisler, Vergel, LEF Foundation, etc., recommend between 20 - 30 on a sensitive assay. Also know that standard estradiol is geared toward women and tends to read higher for men, thus resulting in the unnecessary use of aromatase inhibitors. Again, the top docs will tell you this. Google LEF and Estrogen and you'll find some good articles. 1 mg x 3 per week would crash your E2 in no time. Educate her.