Test + Tren IGF1 Question

[DocToxin8]

I'm not seeing anything new here.
Tren is an anabolic steroid with a high androgenic effect,
but it is still an anabolic steroid; and thus less androgenic than testosterone.

It does not 5 alpha reduce to a stronger androgen, but is nearly as strong as DHT in itself.
Neither does it convert to estrogen.

That it has less impact on the prostate and more myotrophic effect than testosterone is pretty fucking obvious, that's why anabolic steroids were developed in the first place.
Nandrolone is also a SARM as such, more so than tren, as it actually converts to a milder androgen in prostate, scalp and tissues rich in 5-AR.

That trenbolone would be a valuable addition to TRT as a myotrophic agent is obvious. At least if one could discern what negative impacts it would have on lipids, etc compared to a higher test dose.

I just don't see what's new here.

But I've only read the abstract.

[MuscleScience]

I'm not seeing anything new here.
Tren is an anabolic steroid with a high androgenic effect,
but it is still an anabolic steroid; and thus less androgenic than testosterone.

It does not 5 alpha reduce to a stronger androgen, but is nearly as strong as DHT in itself.
Neither does it convert to estrogen.

That it has less impact on the prostate and more myotrophic effect than testosterone is pretty fucking obvious, that's why anabolic steroids were developed in the first place.
Nandrolone is also a SARM as such, more so than tren, as it actually converts to a milder androgen in prostate, scalp and tissues rich in 5-AR.

That trenbolone would be a valuable addition to TRT as a myotrophic agent is obvious. At least if one could discern what negative impacts it would have on lipids, etc compared to a higher test dose.

I just don't see what's new here.

But I've only read the abstract.

I read some papers a few years back that the author described Tren as the
Ultimate SARM.

[hammerheart]

I'm not seeing anything new here.
Tren is an anabolic steroid with a high androgenic effect,
but it is still an anabolic steroid; and thus less androgenic than testosterone.

It does not 5 alpha reduce to a stronger androgen, but is nearly as strong as DHT in itself.
Neither does it convert to estrogen.

That it has less impact on the prostate and more myotrophic effect than testosterone is pretty fucking obvious, that's why anabolic steroids were developed in the first place.
Nandrolone is also a SARM as such, more so than tren, as it actually converts to a milder androgen in prostate, scalp and tissues rich in 5-AR.

That trenbolone would be a valuable addition to TRT as a myotrophic agent is obvious. At least if one could discern what negative impacts it would have on lipids, etc compared to a higher test dose.

I just don't see what's new here.

But I've only read the abstract.

Maybe nothing new in the underground but I'm sure you will understand things works differently in the academic and medical fields (still an old-ish article though).

As for Tren being less androgenic than Test I'd tend to disagree, or better, I believe it to be tissue dependent, otherwise the compound won't be notorious for being harsher on the brain than Test, especially in the regards of aggression, libido and confidence all of which are considered to be androgen-dependent traits.

[MuscleScience]

Maybe nothing new in the underground but I'm sure you will understand things works differently in the academic and medical fields (still an old-ish article though).

As for Tren being less androgenic than Test I'd tend to disagree, or better, I believe it to be tissue dependent, otherwise the compound won't be notorious for being harsher on the brain than Test, especially in the regards of aggression, libido and confidence all of which are considered to be androgen-dependent traits.

I think the talk about Harshness is urban myth or Bro science. I mean shut down is shut down. Whether you are suppressed with Test, or Deca or Tren, what does it matter? Maybe having prolactin sides versus E2 sides is perceived as more harsh, I don't know where it came from.

[DocToxin8]

I think the talk about Harshness is urban myth or Bro science. I mean shut down is shut down. Whether you are suppressed with Test, or Deca or Tren, what does it matter? Maybe having prolactin sides versus E2 sides is perceived as more harsh, I don't know where it came from.

That would be interesting to study.

Even my endo thought tren was the devil as far as fertility goes,
but that doesn't mean he thought it harder to recover from.

One thing is for sure though,
Progestins shut you down!

So while some might not be totally shut down on test alone,
(In trials were it's used as a anti fertility/prevention drug)
Test + a progestin is surer to cause azospermia.

But if it's harder to recover once it's out of the system is another matter.
I don't know.

It might figure that if you manage to keep LH and FSH just a tiny bit alive,
instead of at nil all the time, recovery (of the pituitary) might be easier,
But I'd love to see a study on that.

[MuscleScience]

That would be interesting to study.

Even my endo thought tren was the devil as far as fertility goes,
but that doesn't mean he thought it harder to recover from.

One thing is for sure though,
Progestins shut you down!

So while some might not be totally shut down on test alone,
(In trials were it's used as a anti fertility/prevention drug)
Test + a progestin is surer to cause azospermia.

But if it's harder to recover once it's out of the system is another matter.
I don't know.

It might figure that if you manage to keep LH and FSH just a tiny bit alive,
instead of at nil all the time, recovery (of the pituitary) might be easier,
But I'd love to see a study on that.

That brings up a good point about male contraceptives. I would think that this
Would have been studied in the last 30 years at some point. If it does indeed cause complete shut down I would think it would be all over the journals if it was studied in that capacity.

[DocToxin8]

Maybe nothing new in the underground but I'm sure you will understand things works differently in the academic and medical fields (still an old-ish article though).

As for Tren being less androgenic than Test I'd tend to disagree, or better, I believe it to be tissue dependent, otherwise the compound won't be notorious for being harsher on the brain than Test, especially in the regards of aggression, libido and confidence all of which are considered to be androgen-dependent traits.

In the brain there's at least aromatase, probably 5-AR too,
but since tren is nearly DHT (in AR affinity), it stands to reason it should be more androgenic in the brain that T.