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Thread: Clomid Alone for Hormone Boost?

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  1. #1
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    Quote Originally Posted by Youthful55guy View Post
    I don't normally reply to guys using TRT drugs for non TRT reasons (i.e., bodybuilding), but I feel compelled to advise against going off the rails of standard BB protocols. Whenever you interrupt the natural secretion of hormones in the body, there is a cascade effect throughout the body. Yes, clomid may temporarily increase LH secretion by selectively inhibiting negative feedback on GnRH secretion, but what happens next? Are you prepared to handle the increased conversion to E2? And what about the side-effects of clomid? I've done a little experimenting with clomid as a replacement for HCG, and my experience is that it definitely will have estrogenic side-effects at 50 mg 3X per week.

    My advice, is not to screw up your endocrine system with exogenous hormones or analogs (like clomid), bit if you are going to do it, that you stick to established protocols and not try to reinvent the wheel.
    I'm not understanding your logic that there will be increased estrogen side effects when the serm (clomid) blocks estrogen at the receptor so until he stops he should see and feel nothing from it imho...maybe because you where not taking it everyday idk...the theory here is to block the estrogen to possibly raise free test but in reality even though that may be true it is so short lived its not worth it or everyone would be doing it...if your test levels are good for your age why in gods name do you want to disrupt it...

  2. #2
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    Quote Originally Posted by ghettoboyd View Post
    I'm not understanding your logic that there will be increased estrogen side effects when the serm (clomid) blocks estrogen at the receptor so until he stops he should see and feel nothing from it imho...maybe because you where not taking it everyday idk...the theory here is to block the estrogen to possibly raise free test but in reality even though that may be true it is so short lived its not worth it or everyone would be doing it...if your test levels are good for your age why in gods name do you want to disrupt it...
    I'm not an expert on Clomid, but I was under the impression that it was very selective to blocking E2 receptors in the hypothalamus, where it prevents the negative feedback on GnRH production. Clomid itself has estrogenic side-effects too. While weak in that regard, it does have estrogenic side-effects. My experience is that they become noticeable (for me anyway) at doses that exceed about 12 mg per day. They are mostly CNS side-effects similar to low T effect on the brain.

  3. #3
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    Quote Originally Posted by Youthful55guy View Post
    I'm not an expert on Clomid, but I was under the impression that it was very selective to blocking E2 receptors in the hypothalamus, where it prevents the negative feedback on GnRH production. Clomid itself has estrogenic side-effects too. While weak in that regard, it does have estrogenic side-effects. My experience is that they become noticeable (for me anyway) at doses that exceed about 12 mg per day. They are mostly CNS side-effects similar to low T effect on the brain.
    I appreciate your input and experience brother thx...

  4. #4
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    Quote Originally Posted by Youthful55guy View Post
    I'm not an expert on Clomid, but I was under the impression that it was very selective to blocking E2 receptors in the hypothalamus, where it prevents the negative feedback on GnRH production. Clomid itself has estrogenic side-effects too. While weak in that regard, it does have estrogenic side-effects. My experience is that they become noticeable (for me anyway) at doses that exceed about 12 mg per day. They are mostly CNS side-effects similar to low T effect on the brain.
    Any changes in the vision like floaters? Permanent?

  5. #5
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    Quote Originally Posted by dikow View Post
    Any changes in the vision like floaters? Permanent?
    None.

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