Will TRT dose interfere with Pregnancy?

[JuliusPleaser]

take into account my other things I wrote, do you believe TRT at 100 or 200, would interfere with this? Because really my question is do I resume TRT and do PCT with it, or get off totally?

[Youthful55guy]

take into account my other things I wrote, do you believe TRT at 100 or 200, would interfere with this? Because really my question is do I resume TRT and do PCT with it, or get off totally?

Yes, any effective TRT dose will suppress gonadotropins to near zero, so no spermatogenesis. I recommend upping your dose of HCG to 1000 IU per week and make sure that you mind the expiration time after reconstituting and keep it well refrigerated (the colder the better). It looses potency the longer you store it.

There is good data to shows that 1000 IU per week (in split doses) is the magic dose to bring intratesticular testosterone (ITT) levels back to normal, even on 200 mg of T-eth per week. ITT is a marker of fertility.

If you are interested in reading more, here are two good resources:

Coviello, A. D., A. M. Matsumoto, W. J. Bremner, et al. (2005). "Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression." J Clin Endocrinol Metab 90(5): 2595-2602. 18-45 https://www.ncbi.nlm.nih.gov/pubmed/15713727

Ramasamy, R., J. M. Armstrong and L. I. Lipshultz (2015). "Preserving fertility in the hypogonadal patient: an update." Asian journal of andrology 17(2): 197. https://www.ncbi.nlm.nih.gov/pubmed/...t%3A+an+update

[JuliusPleaser]

So, in all logic, I shouldn't remove test totally because I am indeed on TRT, thus to take it all away would do nothing? Thanks for the sources bro

[MuscleScience]

So, in all logic, I shouldn't remove test totally because I am indeed on TRT, thus to take it all away would do nothing? Thanks for the sources bro

Well, at a certain T total level and some other factors high T shuts down sperm production. But so does low T, you want your levels to be in a normal range for your body. That is for optimal swimmer production.

[JuliusPleaser]

Ok, so I think then it best to do 100mg, so I don't crash totally and have no test, as that will put me in normal range since 200mg was putting me at 1500 lol.

Then ill do HCG, clomid... but I'm gonna have to combat the estrogen rebound, so I'm think probably aromasin rather than nolv?

[Youthful55guy]

Ok, so I think then it best to do 100mg, so I don't crash totally and have no test, as that will put me in normal range since 200mg was putting me at 1500 lol.

Then ill do HCG, clomid... but I'm gonna have to combat the estrogen rebound, so I'm think probably aromasin rather than nolv?

From a health perspective, your best bet is to simply optimize your T levels with normal TRT. If that's 100 mg/week for you then go for it. You might want to follow it up with labs in about 4 weeks to see where you are and then adjust if necessary. However, it doesn't really matter how high you go, any level of exogenous T will suppress gonadotropin production. At 100 mg/wk, LH & FSH will pretty much be zero, so more T will not suppress it any further. I do suggest breaking that 100 mg up into smaller doses. This will give you a much smoother ride and control E2 much better. Trust me, you will feel better with smaller and more frequent dosing. I do 40 to 50 mg every 3 days. The smaller doses also allow you to drop down to a 28G insulin syringe. You hardly feel it.

I don't understand what you mean by estrogen rebound. If you mean HCG induced E2 production, yes, there may be some effect. I regularly do 1050 IU HCG per week (450 IU E3D) and my E2 without any E2 control is a bit high (about 60 pg/mL). I use the "vodka method" to dispense very low daily doses of anastrozol (totally about 0.5 mg per week) and that usually keeps it in the 20 to 30 pg/mL range (upper end of the normal range being 35 in this lab).

My advice is to monitor your E2 carefully beginning about 4 weeks after changing the dose and then use E2 control as necessary to keep it in range.

Keep in mind too that it take about 3 months for sperm cells to fully mature and be capable of fertilization (mostly a motility thing). So what you do today will not show up in your ejaculate for another 3 months.

[JuliusPleaser]

I mean the estro rebound from my cycle that is currently 600mg of Cyp and 300mg of Tren A... The 600 cyp, when I drop down to 100mg, will certainly create unstable levels of estogren that need to be handled.