Quote Originally Posted by Garbanzo Dude View Post
Very Interesting.....My TRT Doctor mentioned "he has seen some client's lower SHBG with Danazol, Anavar and Proviron" But flat out told me he would not prescribe these durgs as the "they have a bad rap with the AMA or medical community"

I've always had high SHBG- I think it has to do with those years of hard drinking in my 20's and I have Mild Ulcerative Colitis.......Im 41 now and rarely drink.....UC is under control, but I know high SHBG correlates with high inflammation.

I'm currently on my 12th week of TRT and my last test showed Total Test going down slightly from previous blood test.

So I have read a few times here that 1x per week injection will keep SHBG lower vs. 2x per week. Does anyone know where I can find or reference these studies??


Also has anyone had any luck with Oat Extract or Boron supplements??
To my knowledge, there is no research supporting that statement. My guess is that it's gym lore and probably has no basis in research. I simply don't believe it. Dosing weekly goes contrary to my general philosophy of TRT, which is to prevent the rollercoaster ride with smaller and more frequent dosing. That should control E better and we suspect that high E is one of the factors will drive up SHBG (though I have no references for this).

The drugs you mention have a bad rap with the AMA because they are prone to anabolic steroid abuse. Whenever you misuse drugs, the side-effects go up. Bodybuilders often use 40-100 mg of Winstrol or Anavar per day to achieve their desired effect. At that level, there is MUCH research showing that liver damage is inevitable. That is the main reason they cycle it to allow repair of the damage. My experience is that for SHBG lowering effects you need much small doses (in the 5-10 mg per day range). My experience also shows that my liver labs generally stay within normal when I dose at these low rates. It's only when I add other OTC analgesics to the mix where my liver labs go out of range.