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Thread: Use of MK-677 to boost GH and IGF-1

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  1. #1
    Join Date
    May 2016
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    Quote Originally Posted by Tim1985 View Post
    Youthful,
    You mentioned you used MK-677 in addition to your other peptides. Do you think it would be a waste of money when compared to the results to treat with it by itself? My TRT doc is pitching either using MK-677 at 12.5mg once daily in the evening, or ipamorelin at 500mcgs every night. This would be to boost my IGF-1 (last labwork was 147 with ref range of 88 - 246) and help with joint soreness.
    I plan to put that to the test in future labs. I had no idea that MK-677 existed until a couple months ago. I simply layered onto my existing peptide protocol and got really good results exceeding my target. I like that it's oral and shelf stable (no refrigeration), so it makes the protocol portable during vacations. My long term goal is to reduce the cost of my peptide program while keeping IGF-1 in the 50th percentile for a 25-35 year old man, which is around 200 ng/mL.

    Several weeks ago I reduced the amount of injected peptide and I plan to retest in a couple more weeks. I'll then make dosing decisions and test in another 6 or so weeks. As it is now, I have enough of my peptides to last through June. Eventually I will get to a MK-677 only protocol because I have a 10-day hiking vacation planned in July. Whether I go back to a combination protocol has yet to be determined.

    Regarding your doctor's recommended dose, It seems a bit low. Granted, my baseline was lower at around 116 (AVG of 4 tests). When I layered 25-30 mg MK-677 daily (~13-15mg AM and ~13-15mg PM) onto my existing 900/300 mcg Ipamorelin/CJC-1295 (no DAC) protocol, it pushed my level from about 160 to 220. I doubt that 30 mg/day would be enough to sustain my target IGF-1 level (200).

  2. #2
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    Quote Originally Posted by Youthful55guy View Post
    I plan to put that to the test in future labs. I had no idea that MK-677 existed until a couple months ago. I simply layered onto my existing peptide protocol and got really good results exceeding my target. I like that it's oral and shelf stable (no refrigeration), so it makes the protocol portable during vacations. My long term goal is to reduce the cost of my peptide program while keeping IGF-1 in the 50th percentile for a 25-35 year old man, which is around 200 ng/mL.

    Several weeks ago I reduced the amount of injected peptide and I plan to retest in a couple more weeks. I'll then make dosing decisions and test in another 6 or so weeks. As it is now, I have enough of my peptides to last through June. Eventually I will get to a MK-677 only protocol because I have a 10-day hiking vacation planned in July. Whether I go back to a combination protocol has yet to be determined.

    Regarding your doctor's recommended dose, It seems a bit low. Granted, my baseline was lower at around 116 (AVG of 4 tests). When I layered 25-30 mg MK-677 daily (~13-15mg AM and ~13-15mg PM) onto my existing 900/300 mcg Ipamorelin/CJC-1295 (no DAC) protocol, it pushed my level from about 160 to 220. I doubt that 30 mg/day would be enough to sustain my target IGF-1 level (200).
    Have you noticed any of the sluggishness that I’ve heard of when using MK?

  3. #3
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    May 2016
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    Quote Originally Posted by Family_guy View Post
    Have you noticed any of the sluggishness that I’ve heard of when using MK?
    No. Not at all. In fact, no side effects at all. At first I even questioned the potency of the product (new source for me), but the test results were conclusively positive.

  4. #4
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    Quote Originally Posted by Youthful55guy View Post
    No. Not at all. In fact, no side effects at all. At first I even questioned the potency of the product (new source for me), but the test results were conclusively positive.
    Very interesting

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