Aromatization

[Slacker78]

there are something like 15 different types of estrogen.. Nolva is a strong binding estrogen , but is "selective" (hence being a SERM) in its action and receptor binding.. so for example it has a strong binding affinity to bind to receptors in breast tissue, BUT it also does not promote any of the effects on that tissue that something like E2 would have on the same receptor. E2 then competes for this breast tissue receptor but can't bind cause the Nolva is bound, but the E2 is still free and able to bind to more important tissues like those in the brain and vascular system to illicit their positive benefits.

the only long term issue that I'm aware of with Nolva, at higher doses, is its lowering of hepatic IGF output. but this is not an issue for steroid users, as the use of AAS and other growth factors that greatly increase IGF more then makes up for this small lowering effect. plus muscle cells have the ability to produce IGF on their own without the need from hepatic IGF.

but either way.. I would not set you cycles up or your TRT up in such a way that you would need to be on a SERM long term anyways.

personally, I've ran 2000mg of test per week with no AI and no SERM .. but I'm one of the lucky ones that have no issues with gyno. as gyno is genetic and guys that get it can get it wither they use an AI or not, and some guys like me seem to have no estrogen receptors in breast tissue to begin with.

Clear. I suppose it could be a good practice use Nolva during a cycle and switch to AI when returning in TRT if estrogens would be a problem even on TRT course. I would prefer Nolva administration while on cycle in absolute sense, given the facts.

It's not a coincidence if when i left my estrogens increase, my muscle mass gains were very remarkable; and it's not a coincidence neither, if Dbol is a king of muscle mass gains.

I wondering if even under Nolva, over the Gyno, we could experiment the others high estrogens effect, being just a specific kind of receptors we block while others remain free to bind.... i think this could be bound to the subject of the topic related to what asked HoldMyBeer... for these reasons i think he suspected a moderate synergic action of AI... no Gyno ok... but high estrogens = all other typical sides as well as other receptors sites are free to be bound.

[charger69]

Clear. I suppose it could be a good practice use Nolva during a cycle and switch to AI when returning in TRT if estrogens would be a problem even on TRT course. I would prefer Nolva administration while on cycle in absolute sense, given the facts.

It's not a coincidence if when i left my estrogens increase, my muscle mass gains were very remarkable; and it's not a coincidence neither, if Dbol is a king of muscle mass gains.

I wondering if even under Nolva, over the Gyno, we could experiment the others high estrogens effect, being just a specific kind of receptors we block while others remain free to bind.... i think this could be bound to the subject of the topic related to what asked HoldMyBeer... for these reasons i think he suspected a moderate synergic action of AI... no Gyno ok... but high estrogens = all other typical sides as well as other receptors sites are free to be bound.

Dbol - king of muscle mass gains? Can you explain?


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[Family_guy]

It’s nice to have you back Gear!!!

[Slacker78]

Dbol - king of muscle mass gains? Can you explain?


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Dbol converts in methyl estradiol that is four times powerful than estradiol. You can guess the rest, staying to what we discussed here.