03-13-2005, 03:04 PM #1New Member
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- Mar 2005
Oxymetholone (Oxybolone) A.K.A Anabol
I,ve been training now for about 8 months i have had quite a few gains but have hit a flat spot and have purchased some Oxymetholone (Oxybolone) also known as anadrol . i have never taken anything like this before and im new to all this steroid game, any body got on tips on the Oxys e.g what to take with them such as anti estrogens, any bad side efeects etc, some advice would be really great.
i've read a bit abot them and to be honest they sound bad news with the kidney side effects but havent really spoken to anyone tidy who've took them. cheers
03-13-2005, 03:06 PM #2Owner
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- Mar 2002
03-13-2005, 03:08 PM #3
def. run it with test of some kind or all of your gains will be lost. Don't take it for more than 4 or 5 weeks at the begining of your cycle and you should be find. Run nolvadex at 10mg a day throughout. Drink plenty of water. You may also want to take in some liver protectant.
03-13-2005, 03:12 PM #4
i wouldn't recommend anadrol to a 1st time gear user.... but if your going to run it anyways.... i would atleast take 500mg's test/wk for 12 weeks and 1 anadrol tab/day (assuming it's 50mg's/tab)
1-4 anadrol 50mg's/day
1-12 test enth or cyp 500mg's/wk
anadrol can bloat pretty bad..... not only that but without test... your going to lose almost everything.... anadrol will add water weight, making you think your getting bigger.... adding muscle..... In the process of adding this water weight... it will shut down your natural test production. So when you come off the anadrol.... and shed all the water you gained.... you now wont have normal levels of testosterone thus setting stage for more weightloss.... potentially ending up lighter than when you started....
don't run the abombs without test.... just my .02
Last edited by Hazard; 03-13-2005 at 03:14 PM.
03-13-2005, 03:59 PM #5Writer
Originally Posted by system admin
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[17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one]
Molecular Weight: 332.482
Molecular Formula: C 21 H 32 O 3
Melting Point: 178-180C
Manufacturer: Syntex (Originally)
Release Date: 1960
Effective Dose: 100mgs (optimal)
Active Life: <16hours
Detection Time: up to 8 weeks
Androgenic: Anabolic Ratio: 45:320
Anadrol (commonly called by athletes “A50” or “A-bombs”) was initially developed as a compound to help people with anemia, and has since been used very successfully to aid people who are suffering from many other diseases where weight loss is a concern. Thus, it is clearly an effective agent for promoting weight gain, increasing appetite, gaining strength, and increasing Red Blood Cell count. And, as with most Anabolic /Androgenic Steroids (AAS), it has it’s downsides as well. Anadrol will inhibit your body’s natural production of hormones (testosterone , etc…), will negatively affect your blood lipid profile, can cause water retention, is notorious for causing headaches, and is also highly liver toxic (in fact, it has the worst reputation for hepatoxicity out of all steroids). Paradoxically, although one the benefits touted by it’s original manufacturer (Syntex) is that it can be used to stimulate weight gain through increasing appetite, taking too much may actually inhibit your appetite!
I think, in order to gain a complete understanding of this compound, we need to take a look at its advantages contrasted with its disadvantages. Anadrol is a DHT-derived compound, and is 17-Alpha-Alkylated steroid , meaning that it has been altered at the 17th carbon position to survive oral ingestion. Most oral steroids are 17aa, and this helps them make it through your liver in a useful form. Sounds great, right? Lets 17alpha-alkylate everything! Well…as you can imagine, there’s a down side. This 17aa alteration, which makes it possible for Anadrol to survive its first pass through your liver, also makes it very taxing on your liver. How taxing is A50 and how much weight can you gain from its use? Well, there was a 30 week study done on A50 and, as you can expect, a reasonable amount of side effects were noted. The fact that A50 causes some side effects has really never been in debate. But how effective was the drug? Well, first it should be mentioned that this study was done on people with AIDS related wasting, and they actually gained weight (8+kg) while the control group lost weight, and had increased mortality rates. (1). I suppose, if you’re in a study because you have a wasting disease which is also a terminal illness, you don’t want to end up in the control group….Anyway, weight gain in this study peaked at 19-20 weeks, though, so the last 10 weeks weren’t very productive in this respect. Clearly, you wouldn’t want to run Anadrol for 20 weeks, given its toxicity, but after that, any effect in terms of weight and strength gains would be negligible. So, with regards to sides from Anadrol, and the sheer fact that this study lasted so long (30 weeks), it should be apparent that they can be kept under control and the drug can be used safely. People are commonly told to limit their intake of A50 to 4 weeks or less…I’m a bit less conservative and think you can easily run A50 for 6 weeks or more.
From personal experience, however, I can tell you that gains from Anadrol are quite dramatic for the first 3 weeks, and then quickly level off. Unfortunately, I find that the side effects experienced from Anadrol (which include a headache, bloating, elevated blood pressure, and a general “unwell” feeling for me) remain for the entire duration of use….but I find, as usual, side effects for this drug are pretty much half legend and half truth. Since Anadrol is derived from DHT, it can’t actually convert to estrogen (via the aromatase enzyme), and it’s not a progestin or a compound with progestenic activity…so the estrogenic (?) side effects produced by it are of a very mysterious nature. It has been speculated that perhaps it can stimulate the estrogen receptor without actually being converted to estrogen…that’s about as plausible an explanation as I’ve heard…One would expect that an AI (aromatase inhibitor) wouldn’t be of much use with this drug, but many have found that Letrozole (which has, in some cases been shown to reduce estrogen in the body to an undetectable amount)(6) can greatly reduce or even eliminate many of the more noticeable side effects of Anadrol, such as the bloating.
As I’ve stated, however, the sides from this drug are certainly no joke, but are easily preventable, and controllable. One study even showed very few sides for subjects using up to 100mgs of Oxymetholone (2). In the original UnderGround Steroid HandBook, Dan Duchaine states that he used it at doses up to 150mgs/day. Clearly, Anadrol’s hepatoxicity has been a bit exaggerated, in some circles. Be that as it may, my suggestion is still to limit Anadrol’s use to 6 weeks, at a maximum…even if just to err on the side of caution. Of course, I have personally run this drug for much longer…
How should we use Anadrol? I’d probably be willing to include Anadrol in a cycle including injectable steroids, but not other 17aa compounds. I’d make any 6-week-run of this compound begin at the start of a cycle, as a form of “jumpstart” towards seeing gains quickly. The quick gains you will get from Anadrol (up to a pound per day for the first 2 weeks are not uncommon in Steroid.com members) are also just as quick to disappear upon cessation of use….unless you are simply using it as a kickstarter, while waiting for your other compounds to kick-in. I’ll go out on a limb here and say that utilizing Anadrol as a “Jumpstart” is the most popular use of this drug for athletes and bodybuilders today. I’ll also say that this drug is immensely popular with strength athletes who don’t have to worry about weight classes (Field athletes and strongmen), and with powerlifters in the heavier weight brackets. Given the large amounts of weight and strength which can be gained in s relatively short time span on this drug, I’m sure this comes as no surprise to many.
Another important and often understated characteristic of this compound is that Oxymetholone doesn’t bind well to the androgen receptor (Relative Binding Affinity = too low to be determined) (3) which is the lowest I’ve ever read about. Basically, what this tells me is that there are a lot of non-receptor mediated effects from this steroid, making it a very potent addition to ANY BULKING stack, because it won’t be competing for the receptor sites with the other steroids you’re using. It’s also, as you may have guessed a very poor choice for a cutting stack.
How much should you use? Well, this is actually one of the most interesting facts about Anadrol. You see, most steroids produce what we call a “dose respondent curve” which is a fancy way of saying “the more you use, the more you gain.”
Anadrol is one of the few steroids where the dose respondent curve flattens out very quickly. When you take 50mgs of Anadrol, you’ll make some very good gains. When you take 100mgs of Anadrol, you’ll make even more gains. However, it has been found that 100mgs/day is as effective for weight gain as 150mgs/day but produces less side effects and was less toxic (4). I feel that the jump from 50mgs to 100mgs constitutes an acceptable rise in benefit vs. cost, but this is not the case as dosages get over 100mgs. Although I am usually not inclined to posit speculations on why a particular drug does or doesn’t do something, in this case I will. I’m guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day.
This steroid is very available on the black market in the form of capsules, tablets (some are even 75mgs!), liquid, and even paper. Prices will vary, and be indicative of many different factors including the form you buy this compound in (paper will usually be the most expensive, and liquid the least), and where you live. In any case, you shouldn’t be paying more than $2.50-3.00 per 50mgs.
1. Br J Nutr. 1996 Jan;75(1):129-38.
2. Schroeder et al. Am J Physiol Endocrinol Metab 284:E 120-28
3. Endocrinology. 1984 Jun;114(6):2100-6.
4. HIV Clin Trials. 2003 May-Jun;4(3):150-63.
5. J Clin Endocrinol Metab. 1981 Nov;53(5):905-8
6. Epilepsy Behav. 2004 Apr;5(2):260-3
03-13-2005, 04:59 PM #6
**** Hooker awesome post man
03-13-2005, 06:58 PM #7Writer
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03-13-2005, 07:50 PM #8New Member
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03-14-2005, 03:13 AM #9New Member
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- Mar 2005
cheers guys, havent started them yet and yes i'am planning on just running the anadrol , think i'll try them for a few days to see how i get on with them, if i get any bad side effects i'll bin them straight away, what you think??
03-14-2005, 06:10 AM #10
Don't waste your time and pills, bro, just take the advices the
bros posted above, that's the way to go!
03-14-2005, 08:41 PM #11Associate Member
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- Dec 2003
Hooker your knowledge is on a genius level... Thanks for the info...
Originally Posted by hooker
03-14-2005, 09:27 PM #12
hooker love your posts you are the ultimate roid monkey . thanks for the post from sallu i love your drug profiles and this one shows your personal views on it great stuff bro. the board loves u .
03-15-2005, 12:02 AM #13Banned
Originally Posted by sigma4
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03-15-2005, 12:04 AM #14Anabolic Member
Originally Posted by saluu
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