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  1. #1
    Atomini's Avatar
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    Proviron *POSSIBLY* anabolic on its own?

    We know that Proviron isn't anabolic in and of itself, but i'm wondering if it's anabolic on it's own in that it frees up total testosterone . Can it be anabolic in freeing up total natural testosterone from bound to unbound? I was thinking about that today.

  2. #2
    Swifto's Avatar
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    Its not anabolic in muscle tissue at all I dont think, no.

    It can bind to SHBG, freeing more available testosterone . Also, there is a study (I think 1) stating it raises LH. It also lowers estrogen and may work to raise LH or serum T by this action too...

  3. #3
    Random is offline RETIRED VET
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    Also, there is a study (I think 1) stating it raises LH
    Yea i think ive read that one....but proviron is very weak...it definitely has its places tho, i wouldnt expect much running it by itself tho..


    CD

  4. #4
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    Proviron gets destroyed before reachin the muscle receptor. It is highly anabolic on the prostate gland.

  5. #5
    skipp is offline Senior Member
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    Great bridge IMO...

  6. #6
    Snrf's Avatar
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    I quite like proviron , I ran it for the first 4 weeks of my cycle just cuz I wanted to see if I was gonna be prone to MPB and it kept me hard as a rock even on dbol ...it was pretty cool

  7. #7
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    Quote Originally Posted by Swifto
    Its not anabolic in muscle tissue at all I dont think, no.

    It can bind to SHBG, freeing more available testosterone. Also, there is a study (I think 1) stating it raises LH. It also lowers estrogen and may work to raise LH or serum T by this action too...
    don't forget hair loss.. it does that good too..
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  8. #8
    Swifto's Avatar
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    Quote Originally Posted by spywizard
    don't forget hair loss.. it does that good too..
    Yeah...DHT derivative.

  9. #9
    Swifto's Avatar
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    Quote Originally Posted by CaptainDominate
    Yea i think ive read that one....but proviron is very weak...it definitely has its places tho, i wouldnt expect much running it by itself tho..


    CD
    Effect of non aromatizable androgens on LHRH and TRH responses in primary testicular failure.

    Spitz IM, Margalioth EJ, Yeger Y, Livshin Y, Zylber-Haran E, Shilo S.

    We have assessed the gonadotropin, TSH and PRL responses to the non aromatizable androgens, mesterolone and fluoxymestrone, in 27 patients with primary testicular failure. All patients were given a bolus of LHRH (100 micrograms) and TRH (200 micrograms) at zero time. Nine subjects received a further bolus of TRH at 30 mins. The latter were then given mesterolone 150 mg daily for 6 weeks. The remaining subjects received fluoxymesterone 5 mg daily for 4 weeks and 10 mg daily for 2 weeks. On the last day of the androgen administration, the subjects were re-challenged with LHRH and TRH according to the identical protocol. When compared to controls, the patients had normal circulating levels of testosterone , estradiol, PRL and thyroid hormones. However, basal LH, FSH and TSH levels, as well as gonadotropin responses to LHRH and TSH and PRL responses to TRH, were increased. Mesterolone administration produced no changes in steroids , thyroid hormones, gonadotropins nor PRL. There was, however, a reduction in the integrated and incremental TSH secretion after TRH. Fluoxymesterone administration was accompanied by a reduction in thyroid binding globulin (with associated decreases in T3 and increases in T3 resin uptake). The free T4 index was unaltered, which implies that thyroid function was unchanged. In addition, during fluoxymesterone administration, there was a reduction in testosterone , gonadotropins and LH response to LHRH. Basal TSH did not vary, but there was a reduction in the peak and integrated TSH response to TRH. PRL levels were unaltered during fluoxymesterone treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

    PMID: 6437958 [PubMed - indexed for MEDLINE]

    Got ya!


    There are conflicting studies with Proviron though.

  10. #10
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    I run 25mg ED throughout cycle and 50mg during PCT

  11. #11
    Atomini's Avatar
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    Quote Originally Posted by davedizzle
    I run 25mg ED throughout cycle and 50mg during PCT
    Any hairloss or prostate hypertrophy?

    I've heard that even though Proviron is a DHT derivative, it's fairly mild when it comes to that.

  12. #12
    davedizzle's Avatar
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    Quote Originally Posted by Atomini
    Any hairloss or prostate hypertrophy?

    I've heard that even though Proviron is a DHT derivative, it's fairly mild when it comes to that.
    No sides.. on Deca aswell.. no hair loss

  13. #13
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    Proviron is actually an androgenic ....

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