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08-27-2010, 04:28 AM #1
Can genetic gyno be fixed without surgery???
Ok so i first noticed i had gyno when i was in my early teens, (not that i knew what it was back then). saw my gp, he said it would go away blah blah blah.
My gyno isnt huge but definately noticeable, looks like i have two sad eyes under my t shirt!
could this be fixed with any serms, letrozol/ nolva? or would surgery be my only option seeing as i have had it for so long?
cheers.
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08-27-2010, 04:38 AM #2Associate Member
- Join Date
- Jul 2010
- Posts
- 150
got the exact same thing from early teens, not major but can notice, I have done quite a bit of searching but have not come up with much regarding easy reversal. other then surgery.......
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08-27-2010, 04:40 AM #3
Same problem here, any answers ?
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Yes. there's many, many studies showing that pubertal/idiopathic gyno can be relieved by using SERMs (nolva/ralox) and AI's.
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http://www.ncbi.nlm.nih.gov/pubmed/3088241:
Abstract
Four boys with persistent pubertal gynecomastia were given intramuscular dihydrotestosterone heptanoate (DHT-hp) at 2 to 4-week intervals for 16 weeks. By the end of treatment, breast size in all four boys had decreased 67% to 78%. Initial plasma levels of gonadotropins, estradiol, testosterone , and dihydrotestosterone (DHT) were normal. Mean plasma DHT concentration rose with the injections of DHT-hp, and remained elevated throughout the treatment period. Estradiol, LH, FSH, and testosterone decreased during treatment, as did 24-hour urinary LH and FSH. No regrowth of breast tissue was observed 6 to 15 months after treatment, although hormone concentrations had returned to near pretreatment values by 2 months after the last injection. DHT-hp has potential to be an effective medical therapy for persistent pubertal gynecomastia.
http://www.ncbi.nlm.nih.gov/pubmed/15238910
Abstract
OBJECTIVES: To assess the efficacy of the anti-estrogens tamoxifen and raloxifen in the medical management of persistent pubertal gynecomastia.
STUDY DESIGN: Retrospective chart review of 38 consecutive patients with persistent pubertal gynecomastia who presented to a pediatric endocrinology clinic. Patients received reassurance alone or a 3- to 9-month course of an estrogen receptor modifier (tamoxifen or raloxifene).
RESULTS: Mean (SD) age of treated subjects was 14.6 (1.5) years with gynecomastia duration of 28.3 (16.4) months. Mean reduction in breast nodule diameter was 2.1 cm (95% CI 1.7, 2.7, P <.0001) after treatment with tamoxifen and 2.5 cm (95% CI 1.7, 3.3, P <.0001) with raloxifene. Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients.
CONCLUSION: Inhibition of estrogen receptor action in the breast appears to be safe and effective in reducing persistent pubertal gynecomastia, with a better response to raloxifene than to tamoxifen. Further study is required to determine that this is truly a
treatment effect.
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I found these with some brief searches.
So take your time and don't be afraid of research
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08-27-2010, 07:46 PM #6Associate Member
- Join Date
- Jul 2010
- Posts
- 150
interesting.... I am doing my first cycle in the next few weeks and have my full pct ready so will see if there is any difference after that.
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08-27-2010, 10:40 PM #7
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08-28-2010, 07:31 AM #8
nothing worked for me
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