Ditch your MILKTHISTLE - pick up TUDCA...

**DigitalGorilla** · 07-05-2012, 12:07 AM

Just wanted to share what I read on here - and then did more research on. Tudca is great for the liver....look into it. Gives me heart burn but Ill deal

**Atomini** · 07-05-2012, 04:30 AM

All the important details are in my giant liver thrad

**C26_H40_O3** · 07-05-2012, 10:52 AM

What is the difference between TUDCA compared to the UDCA that ar-r sells?

**Atomini** · 07-05-2012, 01:09 PM

No difference, really. TUDCA is UDCA with a taurine amino acid attached to the UDCA molecule. Hence the name Tauroursodeoxycholic acid. It simply converts to UDCA when in your body.

There have been claims made that TUDCA is 'superior' to UDCA in bioavailability to the body, but this has never been proven in any studies or anything. In the end, they're the same damn thing.

**C26_H40_O3** · 07-05-2012, 01:44 PM

Originally Posted by Atomini

No difference, really. TUDCA is UDCA with a taurine amino acid attached to the UDCA molecule. Hence the name Tauroursodeoxycholic acid. It simply converts to UDCA when in your body.

There have been claims made that TUDCA is 'superior' to UDCA in bioavailability to the body, but this has never been proven in any studies or anything. In the end, they're the same damn thing.

Thanks for the info

**tballz** · 07-05-2012, 02:25 PM

Originally Posted by Atomini

No difference, really. TUDCA is UDCA with a taurine amino acid attached to the UDCA molecule. Hence the name Tauroursodeoxycholic acid. It simply converts to UDCA when in your body.

There have been claims made that TUDCA is 'superior' to UDCA in bioavailability to the body, but this has never been proven in any studies or anything. In the end, they're the same damn thing.

I was wondering what the 'T' was.

I personally only use udca and am very grateful ar-r carries it.

**Juced_porkchop** · 07-05-2012, 02:58 PM

Originally Posted by tballz

I was wondering what the 'T' was.

I personally only use udca and am very grateful ar-r carries it.

Same here!

ar-r Stocks this, I keep telling people NVM with milthistle pick up UDCA! I mean i do beleve milkthistle helps the body, but detox/protect liver maybe not so much.

**C26_H40_O3** · 07-05-2012, 03:53 PM

Is UDCA liquid or caps?

**tballz** · 07-05-2012, 04:15 PM

Originally Posted by C26_H40_O3

Is UDCA liquid or caps?

It's the one research chem they have that comes in caps.

**Atomini** · 07-05-2012, 05:02 PM

Originally Posted by Juced_porkchop;6064***

Same here!

ar-r Stocks this, I keep telling people NVM with milthistle pick up UDCA! I mean i do beleve milkthistle helps the body, but detox/protect liver maybe not so much.

Milk thistle is bullshit. You should check out my liver thread.

**bigpapabuff** · 07-05-2012, 05:16 PM

I only use udca. It helps lower cholesterol too. Ar-r 's is 250mg a cap so I only take it twice a week while on cycle.

**Atomini** · 07-05-2012, 05:26 PM

Originally Posted by bigpapabuff

I only use udca. It helps lower cholesterol too. Ar-r's is 250mg a cap so I only take it twice a week while on cycle.

You should actually be using far more and far more frequently than that. At that frequency and dose, it's almost negligible.

You should take 500mg PER DAY for liver maintenance while on cycle. 1,000mg or more per day for liver repair if you have done lots of damage from heavy oral use and/or you have high liver enzyme readings from a blood test, etc. The medical studies done on UDCA/TUDCA on people with liver disorders were using 1,500 - 2,000mg per day for repair purposes.

See my liver thread for more information.

**bigpapabuff** · 07-05-2012, 07:05 PM

I've read otherwise. 500-1000mg/week was sufficient. I don't do orals.

**Atomini** · 07-05-2012, 07:23 PM

Originally Posted by bigpapabuff

I've read otherwise. 500-1000mg/week was sufficient. I don't do orals.

Ah, gotcha. I was under the impression you were using it to offset the effect of orals. That's different, then.

**sharmabrah** · 07-05-2012, 07:45 PM

Would Australians be able to get their hands on this product or similar products?

**bigpapabuff** · 07-05-2012, 09:06 PM

Originally Posted by sharmabrah

Would Australians be able to get their hands on this product or similar products?

Order it from Ar-r .com.

**beerdogg** · 07-05-2012, 09:17 PM

I would pick up some TUDCA if I can find it. Everywhere I look on the net its sold out.

**ata1979** · 07-06-2012, 12:53 AM

Thanks for the heads up... I'll check it out

**tballz** · 07-06-2012, 07:37 AM

What's the significance of taurine attached to it? Can't you just supplement taurine with udca?

**Atomini** · 07-06-2012, 08:51 AM

Originally Posted by tballz

What's the significance of taurine attached to it? Can't you just supplement taurine with udca?

Supplementing taurine with it is NOT the same as it being tauroursodeoxycholic acid, where the taurine amino acid is actually chemically bonded to the ursodeoxycholic acid structure. That's like saying throwing wheels in the back of the trunk of your car is the same thing as driving with the wheels ON the car. As I mentioned prior, TUDCA is claimed to provide superior bioavailability over straight UDCA. But it hasn't been proven.

TUDCA is just a conjugate of UDCA. They are the exact same thing, they do the same job, they are reduced to the same stuff when processed in the GI tract.

http://onlinelibrary.wiley.com/doi/1...030.x/abstract

http://www.gastrojournal.org/article...*45-3/abstract

EDIT:

From the first link:

Conclusions
After oral administration of TUDCA and UDCA, no significant differences in their absorption and in biliary bile acid secretion exist. Whether biliary enrichment with taurine conjugates of UDCA instead of glycine conjugates offers advantages in the treatment of cholestatic liver disease is unclear at present.

From the second link:

COnclusions: Low doses of TUDCA and UDCA protect Hep G2 cells from EtOH-induced cytotoxicity. However, TUDCA seems to be more effective than UDCA in reversing the damage.

**loudee16** · 07-06-2012, 03:08 PM

I can find it in powder form 5 grams... Is it good and what do I do with the powder

**Atomini** · 07-06-2012, 03:11 PM

Originally Posted by loudee16

I can find it in powder form 5 grams... Is it good and what do I do with the powder

Wow, 5 grams per... scoop? Teaspoon? 5 grams in the whole container?

Where did you find it?

You need to take 500mg per day for liver health maintenance if on a cycle with orals or whatnot, and 1000mg or more per day for repair from liver damage.

**loudee16** · 07-06-2012, 03:12 PM

So what do I do with the powder .. How do I measure it out?

**Atomini** · 07-06-2012, 03:15 PM

You need to answer my questions first before I can determine how to measure it. What does it say on the bottle?

Once again, you said you got it "in powder form, 5 grams". 5 grams per what? Scoop? Teaspoon? 5 grams in the whole container?

I can't tell you anything if I don't know what the bottle says about the concentration...

**dogtags** · 07-06-2012, 03:15 PM

Originally Posted by ata1979

Thanks for the heads up... I'll check it out

Nice...avitar...

Brb 5 mins

**loudee16** · 07-06-2012, 03:24 PM

Originally Posted by Atomini

You need to answer my questions first before I can determine how to measure it. What does it say on the bottle?

Once again, you said you got it "in powder form, 5 grams". 5 grams per what? Scoop? Teaspoon? 5 grams in the whole container?

I can't tell you anything if I don't know what the bottle says about the concentration...

I didn't get it yet.. But a friend told me where to get it... It says 5 grams 500 servings... Whatever that means... Go on amazon and type in tudca

**Atomini** · 07-06-2012, 03:44 PM

I just looked it up. I don't think you'll know until it arrives. The description on that thing doesn't say how many mg there are in a 'serving'. So, I have no clue here. You'll find out when you get it.