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Thread: Is clen catabolic by itself?
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11-01-2012, 05:30 PM #1
Is clen catabolic by itself?
Interested In taking clen when I start cutting. Is it catabolic if I take it by itself?
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11-01-2012, 05:36 PM #2
Originally Posted by EarlyMuscles
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11-01-2012, 06:15 PM #3
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11-01-2012, 07:15 PM #4
Originally Posted by MuscleInk
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11-01-2012, 07:20 PM #5
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11-01-2012, 07:26 PM #6
No, it's not catabolic. Regardless of anything else you're using with it will not make it catabolic or anabolic . It does, however, have a slight anabolic nature but it is very slight and almost of no consequence in human beings.
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11-01-2012, 07:44 PM #7
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Do you mean that it protects from muscle tissue being catabolized?
Anabolic is different from being anti-catabolic, perhaps you mistook the terms.
Also, do you have a reference to this information?
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11-02-2012, 01:00 PM #8
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11-02-2012, 01:09 PM #9
Originally Posted by ghettoboyd
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11-02-2012, 04:36 PM #10
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Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation
http://ajpendo.physiology.org/content/263/1/E50.short
Abstract
The potent anabolic effects of the beta 2-adrenoceptor agonist clenbuterol on skeletal muscle have been reported to be independent of actions on beta-adrenoceptors. In the present study clenbuterol, presented to rats in the diet (4 mg/kg), caused significant increases in gastrocnemius muscle mass, protein, and RNA content and a decrease in epididymal fat pad mass. These effects were not mimicked by oral administration of the beta 2-adrenoceptor agonist salbutamol even at high dose (52 mg/kg diet), and the effects of clenbuterol were not inhibited by addition of DL-propranolol (200 mg/kg diet). However, the selective beta 2-antagonist ICI-118,551 (200 mg/kg diet) reversed the anabolic effects of clenbuterol, and a high dose of DL-propranolol (1,000 mg/kg diet) also inhibited these actions of clenbuterol. Furthermore, continuous infusion of salbutamol (1.15 mg.kg body wt-1.day-1) via miniosmotic pumps did cause significant increases in muscle mass, protein, and RNA content. These results indicate that the anabolic effects of clenbuterol are dependent on interaction with the beta 2-adrenoceptor. However, a long duration of action appears to be required to induce the anabolic effects of beta 2-agonists.
MG not MCG...?
In my opinion it isn't really up for debate. In fact, based on these doses I would think that it would be rather, what's the word... Difficult to make a convincing argument for clenbuterol being anabolic let alone anti-catabolic..
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