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Thread: Question test 250 does your body get immuned to it

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    Joshprimo is offline New Member
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    Question test 250 does your body get immuned to it

    Here one for you guys what do yous all think will test250 ever stop working in your body if your been on all year round if you been taking 500mg a week the whole year does your body get immuned to it do you need to up your doasge or will test 250 always work

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    kronik420 is offline Anabolic Member
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    GearHeaded is offline BANNED
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    Quote Originally Posted by Joshprimo View Post
    Here one for you guys what do yous all think will test250 ever stop working in your body if your been on all year round if you been taking 500mg a week the whole year does your body get immuned to it do you need to up your doasge or will test 250 always work
    it does not get ''immune'' as Test is a natural male hormone needed for many functions in the body. however if your blasting Test at supra-physiological dosages then after a period of time your body is going to up-regulate Myostatin (Myostatin is a catabolic hormone that prevents your body from putting on un-neccessary muscle mass).

    So basically Myostatin is going to counter the muscle building effects of Test and your going to get to a point where its difficult to put on any more size . This is where you need to either get off of Test for awhile, or introduce new anabolic growth factors to the body that do NOT up-regulate Myostatin , like HGH, IGF, Insulin (your body can continue growing without an increase of Myostatin) . Or, you need to introduce other Anabolics that work though slightly different mechanisms of action , like Tren for example will increase IGF1 production.


    imo , its best to not stay at a high dose of test year round . Myostatin will just be up-regulated year round and your not going to grow (unless your a newb and your getting those first cycle newb gains ,, but after a few years of being on gear and training, 500mg a week of test isn't going to do much for you as far as growth, its just going to allow you to maintain).

    so either come off for 6+ weeks and down regulate Myostatn and re-sensitize, or learn to stack other compounds and growth factors to illicit more gains

  4. #4
    Couchlock is offline Banned
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    Quote Originally Posted by GearHeaded View Post
    it does not get ''immune'' as Test is a natural male hormone needed for many functions in the body. however if your blasting Test at supra-physiological dosages then after a period of time your body is going to up-regulate Myostatin (Myostatin is a catabolic hormone that prevents your body from putting on un-neccessary muscle mass).

    So basically Myostatin is going to counter the muscle building effects of Test and your going to get to a point where its difficult to put on any more size . This is where you need to either get off of Test for awhile, or introduce new anabolic growth factors to the body that do NOT up-regulate Myostatin , like HGH, IGF, Insulin (your body can continue growing without an increase of Myostatin) . Or, you need to introduce other Anabolics that work though slightly different mechanisms of action , like Tren for example will increase IGF1 production.


    imo , its best to not stay at a high dose of test year round . Myostatin will just be up-regulated year round and your not going to grow (unless your a newb and your getting those first cycle newb gains ,, but after a few years of being on gear and training, 500mg a week of test isn't going to do much for you as far as growth, its just going to allow you to maintain).

    so either come off for 6+ weeks and down regulate Myostatn and re-sensitize, or learn to stack other compounds and growth factors to illicit more gains
    Hmmm....

    Now my question is "How can we crash our myostatin levels"?
    Johnhenson likes this.

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